Results 121 to 130 of about 661 (149)

Pregnane alkaloids from Pachysandra axillaris

Steroids, 2010
Nine new pregnane alkaloids, pachysamines J-R (1-9), together with seven known ones, were isolated from Pachysandra axillaris. The chemical structures of the new alkaloids were elucidated by spectroscopic methods. All the compounds were evaluated for their inhibitory activities against HL-60, SMMC-7721, A-549, SK-BR-3, and PANC-1 cell lines.
Yun, Sun, Yu-Xin, Yan, Jian-Chao, Chen, Lu, Lu, Xian-Min, Zhang, Yan, Li, Ming-Hua, Qiu   +6 more
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Pregnane glycosides from Caralluma retrospiciens

Phytochemistry, 1996
Two pregnane ester glycosides were isolated and identified from the alcohol extract of the aerial parts of Caralluma retrospiciens. Their structures were established as 12 beta-benzoyloxy-20-isovaleroyloxy-8 beta,14 beta-dihydroxypregnane-3-O -[beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl -(1-->4)-beta-D-(3-O-methyl-6-deoxy)-galactopyranoside ...
A F, Halim, A T, Khalil
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Pregnane glycosides from Baseonema acuminatum

Fitoterapia, 2001
Two new pregnane glycosides, baseonemoside A and B, were isolated from the aerial parts of Baseonema acuminatum. Their structures were established as pregn-5-ene-3beta,16alpha,20(S)-triol 3-O-beta-D-cymaropyranosyl-(1-->4)-beta-D-digitoxopyranoside 20-O-beta-D-glucopyranosyl-(1-->2)-beta-D-digitalopyranoside 1 and pregn-5-ene-3beta,16alpha,20(S)-triol ...
V E, Rasamison, A L, Okunade, A M, Ratsimbason, E, Rafidinarivo   +3 more
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Pregnane X Receptor‐Mediated Transcription

2005
The pregnane X receptor (PXR, receptor NR1I2) is a ligand-activated transcription factor that is activated by structurally diverse endogenous steroids and foreign chemicals and serves as an important steroid and xenobiotic sensor. This member of the nuclear receptor superfamily is highly expressed in liver and in the gastrointestinal tract, where it ...
Thomas K H, Chang, David J, Waxman
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Pregnane glycosides from Hoodia gordonii

Phytochemistry, 2009
Hoodia gordonii is a 'weight loss' herb, which has gained popularity in the western countries as an appetite suppressant dietary supplement. Phytochemical study of its aerial parts led to isolation of seven pregnane glycosides (hoodigosides W-Z, hoodistanalosides A-B).
Yatin J, Shukla, Rahul S, Pawar, Yuanqing, Ding, Xing-Cong, Li, Daneel, Ferreira, Ikhlas A, Khan   +5 more
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Cytotoxicity of pregnane glycosides of Cynanchum otophyllum

Steroids, 2015
Fourteen new pregnane glycosides, including nine caudatin glycosides (1-9), three qinyangshengenin glycosides (10-12), one kidjoranin glycosides (13) and one gagaminin glycosides (14), along with twelve known analogs (15-26) were isolated from roots of Cynanchum otophyllum Schneid.
Mi, Zhang, Xiang, Li, Cheng, Xiang, Yi, Qin, Jing, He, Bao-Cai, Li, Peng, Li   +6 more
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An a-nor-3-thia-5β-pregnane

Steroids, 1975
Abstract The conversion of a 5β-pregnan-3-one into a 3-thia-A-nor-pregnane is described. The single epimer, characterized as the 5β-isomer by nmr spectroscopy, was obtained. A previous report [1] from this laboratory described the synthesis of the epimeric 3-oxa-A-norpregnan-20-ones 1 and 2 from A-norprogesterone.
C M, Cimarusti, F F, Giarrusso, P, Grabowich, S D, Levine   +3 more
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Study of the cotton effect of 16-substituted 20-keto pregnane and 17α-pregnane derivatives

Tetrahedron, 1964
Abstract A study of the circular dichroism characteristics of various 16-substituted 20-keto pregnane and isopregnane derivatives has been made. The curves of the 16,17-trans compounds are simila to those of the 16-unsubstituted parent compounds. Modifications of functions in rings A and B have little effect, if any, on the circular dichroism maxima ...
P, Crabbé, F, McCapra, F, Comer, A I, Scott   +3 more
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Trimethylsilyl ethers of some 5β-pregnanes

Analytical Biochemistry, 1971
Abstract Trimethylsilyl ethers of five pairs of compounds of the 5β-pregnane series, epimeric at C-20, have been prepared, isolated, and characterized; the derivatives are stable in neutral media. Assignment of configuration at C-20 of a pair may be made on the basis of NMR spectra.
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Pregnane glycosides from Sansevieria trifasciata

Phytochemistry, 1997
Phytochemical analysis of the whole plant of Sansevieria trifasciata, one of the most common Agavaceae plants, has resulted in the isolation of four new pregnane glycosides. Their structures have been determined by spectroscopic analysis and acid- and alkaline-catalysed hydrolysis to be 1 beta,3 beta-dihydroxypregna-5,16-dien-20-one glycosides. This is
Y, Mimaki, T, Inoue, M, Kuroda, Y, Sashida   +3 more
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