The metabolism of pregnenolone in normal subjects and hypertensive individuals.
We have adapted the double isotope derivative assay technique for the measurement of the excretion rate of delta-5-pregnenediol, and applied this method for a comparative study of the metabolism of pregnenolone in normal subjects and hypertensive ...
Silah, Jack G.
core
Pregnenolone can protect the brain from cannabis intoxication
Pregnenolone is considered the inactive precursor of all steroid hormones, and its potential functional effects have been largely uninvestigated. The administration of the main active principle of Cannabis sativa (marijuana), Δ(9)-tetrahydrocannabinol ...
Vallée, Monique +3 more
core
ANTIMICROBIAL ACTIVITY OF PREGNENOLONE-CARBAMAZEPINE COMPLEX ON
In this work the antibacterial activity of pregnenolone-carbamazepine complex was evaluated on S. Aureus, K. pneumoniae and E. coli. The evaluation of antimicrobial effect of the different compounds on the bacterial species was made by the method of ...
María López-Ramos +8 more
core
Antibacterial activity of two pregnenolone-derivatives against Vibrio cholerae and Escherichia coli and its relationship with descriptors LogP, Π [PDF]
In this work the antibacterial activity of two pregnenolone-derivatives was evaluated on V. cholerae and E. coli, using a NCCLS broth dilution modified method.
Díaz, Francisco +5 more
core
In vitro metabolism of pregnenolone to 7 alpha-hydroxypregnenolone by rainbow trout embryos
Tissues taken from rainbow trout embryos at several developmental stages, were incubated in the presence of radioactively-labelled pregnenolone in order to determine the capability of salmonid embryos to metabolize steroids, such as pregnenolone, that ...
Leatherland, J. F. +6 more
core +1 more source
Site and mechanism of BK channel inhibition and cerebral artery constriction by pregnenolone. [PDF]
North KC +6 more
europepmc +1 more source
Novel Steroidal (Thio)barbiturate Hybrids: From Design to Preclinical Assessment in Tumor Therapy. [PDF]
Varges A +12 more
europepmc +1 more source
Correction: Pregnenolone biotransformation by a plant-associated <i>Bulbithecium</i> sp. GSBT E3 and in silico insights. [PDF]
Mancheary John PU +10 more
europepmc +1 more source
Steroid alterations in Cushing's disease persist after remission: ACTH-driven steroid changes dissociate from mood-regulatory neurosteroids. [PDF]
Burhan S +9 more
europepmc +1 more source

