Results 81 to 90 of about 14,331 (219)
Pregnenolone sulfate increases hippocampal acetylcholine release and spatial recognition.
, 2000 International audienceThe pregnenolone sulfate is a neurosteroid with promnesic properties. Recently, a correlation between endogenous levels of pregnenolone sulfate in the hippocampus and performance in a spatial memory task has been reported in aged ...
Darnaudéry, Muriel +9 more
core +1 more source
The TRPP2-dependent channel of renal primary cilia also requires TRPM3.
PLoS ONE, 2019 Primary cilia of renal epithelial cells express several members of the transient receptor potential (TRP) class of cation-conducting channel, including TRPC1, TRPM3, TRPM4, TRPP2, and TRPV4.
Steven J Kleene +6 more
doaj +1 more source
Microbial Hydroxylation of Pregnenolone Derivatives
Chemical and Pharmaceutical Bulletin, 2005 Pregnenolone and pregnenolone acetate were incubated with the fungi Cunninghamella elegans, Rhizopus stolonifer and Gibberella fujikuroi. Incubation of with C. elegans yielded metabolites, 3beta,7beta,11alpha-trihydroxypreg-5-en-20-one, 3beta,6alpha,11alpha,12beta,15beta-pentahydroxypreg-4-en-20-one and 3beta,6beta,11alpha-trihydroxypreg-4-en-20-one ...
Choudhary, Muhammad Iqbal +4 more
openaire +3 more sources
, 2013 Pregnenolone and dehydroepiandrosterone (DHEA) are sex hormone precursors and neuroprotective steroids. Effects of pregnenolone and DHEA may be in part mediated by their conversion to testosterone and by the consecutive conversion of testosterone to ...
García-Segura, Luis M. +2 more
core +1 more source
A Comparison of Salivary Steroid Levels during Diagnostic Tests for Adrenal Insufficiency
Prague Medical Report, 2016 Numerous diagnostic tests are used to evaluate the hypothalamic-pituitary-adrenal axis (HPA axis). The gold standard is still considered the insulin tolerance test (ITT), but this test has many limitations.
Michaela Dušková +12 more
doaj +1 more source
GABAergic neuroactive steroids: a new frontier in bipolar disorders?
Behavioral and Brain Functions, 2012 Neurosteroids are synthesized in the brain and modulate brain excitability. There is increasing evidence of their sedative, anesthetic and antiseizure properties, as well as their influence on mood.
Carta Mauro Giovanni +2 more
doaj +1 more source
, 1973 The urinary excretion of total etiocholanolone and four delta5-3beta-hydroxysteroids viz, pregnenediol, 17alpha-hydroxy-pregnenolone, pregnenetriol and dehydroepiandrosterone isolated from the glucuronide and sulphate fractions by sequential hydrolysis ...
Tan, Eng L.
core
Pregnenolone separation from cholesterol using Sephadex LH-20 mini-columns
, 1980 This article reports a new procedure for the separation of radiolabeled pregnenolone and cholesterol using minicolumns of Sephadex LH-20 and a simple solvent system.
Jefcoate, Colin R. +3 more
core +1 more source
Reproductive Biology and Endocrinology, 2012 Background Since noradrenergic innervation was described in the ovarian follicle, the actions of the intraovarian catecholaminergic system have been the focus of a variety of studies.
Piccinato Carla A +4 more
doaj +1 more source
Pregnenolone decreased the effect of Henkel 100-induced responses in the OE.
, 2016 (A) Representative submerged EOG responses to Henkel 100 (1:5,000) were recorded from the surface of the septum of female mice. Pregnenolone preincubation (1 μM) temporarily reduced the response amplitude.
Paul Scholz (683928) +5 more
core +1 more source