Results 81 to 90 of about 210,811 (163)

The Effects of Pregnenolone 16α-Carbonitrile Dosing on Digoxin Pharmacokinetics and Intestinal Absorption in the Rat [PDF]

, 2010
pharmaceutic
Lowes, Simon, Anna-lena Ungell, Nicholas L. Simmons, Haslam, Iain S., Johan E. Karlsson, Iain S. Haslam, Ungell, Anna-Lena, Hilgendorf, Constanze, Ungell, Anna Lena, Simon Lowes, Fihn, Britt-Marie, Simmons, Nicholas L., Constanze Hilgendorf, Fihn, Britt Marie, Britt-marie Fihn, Karlsson, Johan E., Lowes, Fihn, Karlsson, Hilgendorf, Haslam, Simmons, Ungell   +22 more
core   +1 more source

Pregnenolone Sulfate Activates Basic Region Leucine Zipper Transcription Factors in Insulinoma Cells: Role of Voltage- Gated Ca 2ϩ Channels and Transient Receptor Potential Melastatin 3 Channels □ S

, 2020
The neurosteroid pregnenolone sulfate activates a signaling cascade in insulinoma cells involving activation of extracellular signal-regulated protein kinase and enhanced expression of the transcription factor Egr-1.
Isabelle Mü, Oliver G Rö, Gerald Thiel
core  

Gender differences in the relationships among neurosteroid serum levels, cognitive function, and quality of life

Neuropsychiatric Disease and Treatment, 2018
Chien-Yu Chen,1 Chih-Ching Wu,2,3 Yu-Chi Huang,1 Chi-Fa Hung,1 Liang-Jen Wang4 1Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan; 2Molecular Medicine Research Center, Chang ...
Chen CY, Wu CC, Huang YC, Hung CF, Wang LJ   +4 more
doaj  

Administration Route Differentiation of Altrenogest via the Metabolomic LC-HRMS Analysis of Equine Urine

Molecules
Altrenogest, also known as allyltrenbolone, is a synthetic form of progesterone used therapeutically to suppress unwanted symptoms of estrus in female horses. Altrenogest affects the system by decreasing levels of endogenous gonadotrophin and luteinizing
Madysen Elbourne, John Keledjian, Adam Cawley, Shanlin Fu   +3 more
doaj   +1 more source

Pregnenolone sulfate analogues differentially modulate GABA_A receptor closed/desensitised states. [PDF]

Br J Pharmacol, 2023
Mortensen M, Xu Y, Shehata MA, Krall J, Ernst M, Frølund B, Smart TG.   +6 more
europepmc   +1 more source

Combinatorial Roles of Heparan Sulfate Proteoglycans and Heparan Sulfates in Caenorhabditis elegans Neural Development [PDF]

, 2014
Heparan sulfate proteoglycans (HSPGs) play critical roles in the development and adult physiology of all metazoan organisms. Most of the known molecular interactions of HSPGs are attributed to the structurally highly complex heparan sulfate (HS) glycans.
Kinnunen, Tarja K., Kinnunen Tarja K., Tarja K Kinnunen, Kinnunen, Tarja, Tarja K. Kinnunen (602998)   +4 more
core   +1 more source

Steroidogenic pathway in girls diagnosed with autism spectrum disorders.

PLoS ONE
The diagnostic prevalence of autism spectrum disorders (ASD) shows boys to be more affected than girls. Due to this reason, there is a lack of research including and observing ASD girls.
Katarina Jansakova, Martin Hill, Hana Celusakova, Gabriela Repiska, Marie Bicikova, Ludmila Macova, Katarína Polonyiova, Mária Kopcikova, Daniela Ostatnikova   +8 more
doaj   +1 more source

Cholesterol sulfate and sulfonated steroids.

, 2016
Dot plots of cholesterol sulfate, pregnenolone sulfate (5-pregnen-3β-ol-20-one-3-sulfate), 17-hydroxy-pregnenolone sulfate, androsterone sulfate and epiandrosterone sulfate in the prepubertal group. LOQ stand for limit of quantification.
Fabiana Manservisi (3145254), Fiorella Belpoggi (72722), Alberto Sánchez-Guijo (3145251), Stefan A. Wudy (411343), Sander M. Houten (140355), Jia Chen (8203), Susan L. Teitelbaum (18346)   +6 more
core   +1 more source

The Sulfated Steroids Pregnenolone Sulfate and Dehydroepiandrosterone Sulfate Inhibit the α1β3γ2L GABA_A Receptor by Stabilizing a Novel Nonconducting State. [PDF]

Mol Pharmacol, 2022
Pierce SR, Germann AL, Steinbach JH, Akk G.   +3 more
europepmc   +1 more source

Testing the linearity of the response to combined greenhouse gas and sulfate aerosol forcing [PDF]

, 2004
Detection and attribution studies of the temperature response to anthropogenic greenhouse gases and tropospheric sulfate aerosol have relied on the assumption that the responses to each of these forcings add linearly. Using surface temperature from three
Tett, S. F. B., Gillett, N. P., Wehner, M. F., Weaver, A. J.   +3 more
core   +1 more source