Results 11 to 20 of about 449,800 (228)

Third-Generation Single-Molecule Sequencing for Preimplantation Genetic Testing of Aneuploidy and Segmental Imbalances [PDF]

Clinical Chemistry, 2023
BACKGROUND Current strategies for preimplantation genetic testing for aneuploidy or structural rearrangements (PGT-A/SR) rely mainly on next-generation sequencing (NGS) and microarray platforms, which are robust but require expensive instrumentation.
Vivienne J. Tan, Timing Liu, Zainul Arifin, Beatrice Pak, Arnold S.C. Tan, S. M. Wong, Chiea Chuen Khor, Henry Yang, Caroline Lee, Zhongwei Huang, Mahesh Choolani, Samuel S. Chong   +11 more
openalex   +2 more sources

Chromosomal, gestational, and neonatal outcomes of embryos classified as a mosaic by preimplantation genetic testing for aneuploidy [PDF]

Fertility and Sterility, 2023
Manuel Viotti, Ermanno Greco, J. Grifo, Mitko Madjunkov, Clifford Librach, Murat Çetinkaya, Semra Kahraman, Pavel Yakovlev, N. N. Kornilov, Laura Corti, Anıl Biricik, En‐Hui Cheng, Ching-Ya Su, Maw‐Sheng Lee, Michael Bonifacio, Amber R. Cooper, Darren K. Griffin, Diane Y. Tran, Purvi Kaur, Frank L. Barnes, Christo Zouves, Andrea R. Victor, Andria G. Besser, Svetlana Madjunkova, Francesca Spinella   +24 more
openalex   +2 more sources

A comprehensive preimplantation genetic testing approach for SEA-type α-thalassemia by fluorescent gap-polymerase chain reaction combined with haplotype analysis

Frontiers in Genetics, 2023
Introduction: This study aimed to evaluate the feasibility and necessity of using fluorescence Gap-polymerase chain reaction combined with haplotype analysis in preimplantation genetic testing for SEA-type α-thalassemia.Methods: A total of 26 ...
Jing Wang, Yuanlin Ma, Jing Guo, Rong Li, Canquan Zhou, Yanwen Xu   +5 more
doaj   +1 more source

Introduction - Biopsy: A Major Factor that Can Impact the Clinical Outcome of PGTs

Fertility & Reproduction, 2023
Nowadays, blastocyst biopsy is widely used in preimplantation genetic tests (PGTs), especially in preimplantation genetic testing for aneuploidy (PGT-A).
Ling Chi
doaj   +1 more source

Obstetric, neonatal, and child health outcomes following embryo biopsy for preimplantation genetic testing

Human Reproduction Update, 2023
BACKGROUND Preimplantation genetic testing (PGT) of embryos developed in vitro requires a biopsy for obtaining cellular samples for the analysis. Signs of cell injury have been described in association with this procedure.
A. Alteri, G. Cermisoni, M. Pozzoni, G. Gaeta, P. Cavoretto, P. Vigano'   +5 more
semanticscholar   +1 more source

Preimplantation genetic testing for familial amyloid polyneuropathy

Reproductive Health, 2022
Background Embryo selection in Familial amyloid polyneuropathy eradicates the disease, but the widespread application of preimplantation genetic testing (PGT) for this monogenic disease still requires greater political and clinical commitment.
Mário Sousa
doaj   +1 more source

Embryo ploidy status classification through computer-assisted morphology assessmentAJOG MFM at a Glance

AJOG Global Reports, 2023
BACKGROUND: Preimplantation genetic testing for aneuploidy has been proven to be effective in determining the embryo's chromosomal or ploidy status. The test requires a biopsy of embryonic cells on day 3, 5, or 6 from which complete information on the ...
Gunawan Bondan Danardono, SKom, BEng, Nining Handayani, DVM, MBiomed, Claudio Michael Louis, SKom, BEng, Arie Adrianus Polim, MD, SpOG, DMAS, MBHRE, Batara Sirait, SpOG, Gusti Periastiningrum, SSi, Szeifoul Afadlal, PhD, Arief Boediono, DVM, Ivan Sini, MD, FRANZOG, GDRM, MMIS, SpOG   +8 more
doaj   +1 more source

Prenatal mucopolysaccharidosis VII: A novel pathogenic variant identified in GUSB gene

Clinical Case Reports, 2021
Clinical exome sequencing is a powerful approach to overcome the wide clinical and genetic heterogeneity of mucopolysaccharidosis. These data could be useful for prenatal diagnosis of MPS VII, genetic counseling, and preimplantation genetic testing.
Antonio Miguel Poyatos‐Andújar, Susana García‐Linares, Pilar Carretero, Olga Ocon, Dolores Fresneda, Laura Gort, Francisa Sonia Molina García   +6 more
doaj   +1 more source

Preimplantation genetic testing: A narrative review. [PDF]

Porto Biomed J
Preimplantation genetic testing (PGT) is a diagnostic procedure that has become a powerful complement to assisted reproduction techniques. PGT has numerous indications, and there is a wide range of techniques that can be used, each with advantages and ...
Fernandes SLE, de Carvalho FAG.
europepmc   +2 more sources

Pregnancy is influenced by more than just embryo ploidy: a retrospective study on preimplantation genetic testing. [PDF]

Eur J Med Res
Miao SB, Tian G, Zhao ZC, Wang XW, Zhao J, Geng CP.   +5 more
europepmc   +3 more sources