Results 11 to 20 of about 24,363 (274)

PREIMPLANTATION GENETIC TESTING: Clinical experience of preimplantation genetic testing [PDF]

Reproduction, 2020
Thirty years of rapid technological advances in the field of genetic testing and assisted reproduction have reshaped the procedure of preimplantation genetic testing (PGT). The development of whole genome amplification and genome-wide testing tools together with the implementation of optimal hormonal stimulation protocols and more efficient ...
Martine, De Rycke, Veerle, Berckmoes, Anick, De Vos, Stefanie, Van De Voorde, Pieter, Verdyck, Willem, Verpoest, Kathelijn, Keymolen   +6 more
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PREIMPLANTATION GENETIC TESTING: Preimplantation genetic testing for polygenic disease risk [PDF]

Reproduction, 2020
Since its introduction to clinical practice, preimplantation genetic testing (PGT) has become a standard of care for couples at risk of having children with monogenic disease and for chromosomal aneuploidy to improve outcomes for patients with infertility.
Nathan R, Treff, Diego, Marin, Louis, Lello, Stephen, Hsu, Laurent C A M, Tellier   +4 more
openaire   +2 more sources

Legal Regulation of Preimplantation Genetic Diagnosis: A Comparative Analysis of the Baltic Sea Region and the Nordic Countries

Teisė, 2022
This paper examines the concept and regulation of some of the latest research in the field of fertility – preimplantation genetic diagnosis – in Lithuania, Poland, the Baltic States, and the Nordic countries.
Nastė Grubliauskienė
doaj   +1 more source

Preimplantation genetic testing for aneuploidy in uterus transplant patients

Therapeutic Advances in Reproductive Health, 2021
Uterus transplantation is an emerging treatment for uterine factor infertility. In vitro fertilization with cryopreservation of embryos prior is required before a patient can be listed for transplant.
Rhea Chattopadhyay, Elliott Richards, Valerie Libby, Rebecca Flyckt   +3 more
doaj   +1 more source

A study of application effects of next-generation sequencing based preimplantation genetic testing for aneuploidies in advanced maternal age women

Taiwanese Journal of Obstetrics & Gynecology, 2023
Objective: To investigate if next-generation sequencing-based preimplantation genetic testing for aneuploidies could improve pregnancy outcomes in women of advanced maternal age. Materials and methods: A retrospective analysis.
Yizhuo Yang, Xinmeng Guo, Ming Zhang, Hui Wang, Sha Mu, Hongmei Peng, Yuanqing Yao   +6 more
doaj   +1 more source

Mapping of meiotic recombination in human preimplantation blastocysts

G3: Genes, Genomes, Genetics, 2023
Recombination is essential for physical attachments and genetic diversity. The Han Chinese population is the largest ethnic group worldwide, therefore, the construction of a genetic map regarding recombination for the population is essential.
Yuanlin Ma, Jing Wang, Rong Li, Chenhui Ding, Yan Xu, Canquan Zhou, Yanwen Xu   +6 more
doaj   +1 more source

A comprehensive preimplantation genetic testing approach for SEA-type α-thalassemia by fluorescent gap-polymerase chain reaction combined with haplotype analysis

Frontiers in Genetics, 2023
Introduction: This study aimed to evaluate the feasibility and necessity of using fluorescence Gap-polymerase chain reaction combined with haplotype analysis in preimplantation genetic testing for SEA-type α-thalassemia.Methods: A total of 26 ...
Jing Wang, Yuanlin Ma, Jing Guo, Rong Li, Canquan Zhou, Yanwen Xu   +5 more
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Introduction - Biopsy: A Major Factor that Can Impact the Clinical Outcome of PGTs

Fertility & Reproduction, 2023
Nowadays, blastocyst biopsy is widely used in preimplantation genetic tests (PGTs), especially in preimplantation genetic testing for aneuploidy (PGT-A).
Ling Chi
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Embryo ploidy status classification through computer-assisted morphology assessmentAJOG MFM at a Glance

AJOG Global Reports, 2023
BACKGROUND: Preimplantation genetic testing for aneuploidy has been proven to be effective in determining the embryo's chromosomal or ploidy status. The test requires a biopsy of embryonic cells on day 3, 5, or 6 from which complete information on the ...
Gunawan Bondan Danardono, SKom, BEng, Nining Handayani, DVM, MBiomed, Claudio Michael Louis, SKom, BEng, Arie Adrianus Polim, MD, SpOG, DMAS, MBHRE, Batara Sirait, SpOG, Gusti Periastiningrum, SSi, Szeifoul Afadlal, PhD, Arief Boediono, DVM, Ivan Sini, MD, FRANZOG, GDRM, MMIS, SpOG   +8 more
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Preimplantation genetic testing for familial amyloid polyneuropathy

Reproductive Health, 2022
Background Embryo selection in Familial amyloid polyneuropathy eradicates the disease, but the widespread application of preimplantation genetic testing (PGT) for this monogenic disease still requires greater political and clinical commitment.
Mário Sousa
doaj   +1 more source