Results 1 to 10 of about 3,305 (134)

Preimplantation genetic testing for aneuploidy: challenges in clinical practice [PDF]

Human Genomics, 2022
Preimplantation genetic testing for aneuploidy (PGT-A) has been used widely during in vitro fertilization procedures in assisted reproductive centers throughout the world.
Hui Yang, Andrew Thomas DeWan, Mayur M. Desai, Sten H. Vermund   +3 more
doaj   +4 more sources

Preimplantation genetic testing for aneuploidy in uterus transplant patients

Therapeutic Advances in Reproductive Health, 2021
Uterus transplantation is an emerging treatment for uterine factor infertility. In vitro fertilization with cryopreservation of embryos prior is required before a patient can be listed for transplant.
Rhea Chattopadhyay, Elliott Richards, Valerie Libby, Rebecca Flyckt   +3 more
doaj   +3 more sources

Preimplantation Genetic Testing for Single Gene Conditions and Aneuploidy

Fertility & Reproduction, 2023
It is now over 30 years since the first pregnancies and live births following IVF, embryo biopsy and preimplantation genetic testing (PGT) were reported in 1990. Since then, methods for genetic analysis at the single-cell level have evolved alongside the
Alan Handyside
doaj   +2 more sources

Conventional IVF is feasible in preimplantation genetic testing for aneuploidy. [PDF]

J Assist Reprod Genet, 2023
To investigate the feasibility of the application of conventional in vitro fertilization (cIVF) for couples undergoing preimplantation genetic testing for aneuploidies (PGT-A) with non-male factor infertility.To evaluate the efficiency of sperm whole-genome amplification (WGA), spermatozoa were subjected to three WGA protocols: Picoplex, ChromInst, and
Zhang S, Xie P, Lan F, Yao Y, Ma S, Hu L, Tan Y, Jiang B, Wan A, Zhao D, Gong F, Lu S, Lin G.   +12 more
europepmc   +3 more sources

Preimplantation genetic testing for aneuploidy: predictive embryonic factors. [PDF]

J Assist Reprod Genet
In a preimplantation genetic testing for aneuploidy (PGT-A) cycle, does the blastocyst quality before biopsy, or the day of biopsy, or the embryo hatching status have an impact on either euploidy or the rate of embryo survival after freezing?This was a retrospective study including 6130 biopsied blastocysts coming from 1849 PGT-A cycles performed in ...
Florensa M, Cladellas A, Ballesteros A, Esbert M.   +3 more
europepmc   +3 more sources

Preimplantation genetic testing for aneuploidy: The management of mosaic embryos. [PDF]

Clin Exp Reprod Med, 2022
As the resolution and accuracy of diagnostic techniques for preimplantation genetic testing for aneuploidy (PGT-A) are improving, more mosaic embryos are being identified. Several studies have provided evidence that mosaic embryos have reproductive potential for implantation and healthy live birth.
Yu EJ, Kim MJ, Park EA, Kang IS.
europepmc   +3 more sources

Correlation study of male semen parameters and embryo aneuploidy in preimplantation genetic testing for aneuploidy

Frontiers in Endocrinology, 2023
ObjectiveThe purpose of this study was to evaluate the influence of abnormal semen parameters on embryo aneuploidy based on single nucleotide polymorphism microarray (SNP array).MethodsA total of 464 blastocysts from 103 PGT-A cycles were analyzed.
Hongyi Yang, Yan Liu, Wenbin Niu, Zilan Yang, Yang Wang, Haixia Jin, Gang Li   +6 more
doaj   +3 more sources

Preimplantation genetic testing for aneuploidy: helpful but not a first choice. [PDF]

J Assist Reprod Genet, 2023
This retrospective cohort study aimed to assess and compare the outcomes between cumulative live birth of patients with and without PGT-A and also between prior unsuccessful IVF cycles and PGT-A cycles among patients who experienced IVF but without live birth delivery, and to clarify the effective usage of PGT-A as an in vitro fertilization (IVF) add ...
Ohishi S, Otani T.
europepmc   +3 more sources

Conventional in vitro fertilization enhances preimplantation genetic testing for aneuploidy outcomes in couples with non-male factor infertility [PDF]

Scientific Reports
While extensive research has compared ICSI and c-IVF in general ART outcomes, limited evidence exists regarding their relative efficacy and safety in PGT-A cycles.
Xiaolan Li, Qian Li, Yajie Chang, Shujing He, Yanfang Wang, Xiaoyan Liang, Zhiqiang Zhang   +6 more
doaj   +2 more sources

Retrospective cohort study of preimplantation genetic testing for aneuploidy with comprehensive chromosome screening versus nonpreimplantation genetic testing in normal karyotype, secondary infertility patients with recurrent pregnancy loss

Reproductive and Developmental Medicine, 2019
Objective: To evaluate whether preimplantation genetic testing for aneuploidy (PGT-A) with comprehensive chromosome screening increases live birth rate (LBR) in normal karyotype couples with recurrent pregnancy loss (RPL). Methods: A retrospective cohort
Cai-Xia Lei, Jiang-Feng Ye, Yi-Lun Sui, Yue-Ping Zhang, Xiao-Xi Sun   +4 more
doaj   +4 more sources