Results 21 to 30 of about 3,344 (173)

Evolution and utility of preimplantation genetic testing for monogenic disorders in assisted reproduction - A narrative review

Journal of Human Reproductive Sciences, 2021
Preimplantation genetic testing (PGT) for monogenic disorders and assisted reproductive technology have evolved and progressed in tandem. PGT started with single-cell polymerase chain reaction (PCR) followed by fluorescent in situ hybridisation for a ...
Firuza R Parikh, Arundhati S Athalye, Dhananjaya K Kulkarni, Rupesh R Sanap, Suresh B Dhumal, Dhanashree J Warang, Dattatray J Naik, Prochi F Madon   +7 more
doaj   +1 more source

Molar pregnancy after in vitro fertilization with euploid single embryo transfer

F&S Reports, 2021
Objective: To describe a case of molar pregnancy after in vitro fertilization (IVF) resulting from the transfer of a euploid embryo derived from a monopronuclear zygote. Design: Case report and review of the literature.
Beth Zhou, M.D., Helen Paige Anglin, M.D., Alexander M. Quaas, M.D., Ph.D.   +2 more
doaj   +1 more source

Cost-effectiveness of preimplantation genetic testing for aneuploidies [PDF]

Fertility and Sterility, 2019
To evaluate the economical benefit of preimplantation genetic testing of aneuploidies (PGT-A) when applied in an extended culture and stringent elective single ET framework.Theoretical cost-effectiveness study.Not applicable.None.Comparison of the cost-effectiveness between two IVF treatment strategies: serial transfer of all available blastocysts ...
Edgardo Somigliana, Andrea Busnelli, Alessio Paffoni, Paola Vigano, Alessandra Riccaboni, Carmen Rubio, Antonio Capalbo   +6 more
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Preimplantation Genetic Testing for Aneuploidy – a Castle Built on Sand [PDF]

Trends in Molecular Medicine, 2021
Preimplantation genetic testing for aneuploidy (PGT-A) has become a routine add-on for in vitro fertilization (IVF) to determine whether human embryos are to be clinically utilized or disposed of. Studies claiming IVF outcome improvements following PGT-A, however, used highly selected patient populations or inappropriate statistical methodologies.
Norbert, Gleicher, Pasquale, Patrizio, Ali, Brivanlou   +2 more
openaire   +2 more sources

Introduction - Biopsy: A Major Factor that Can Impact the Clinical Outcome of PGTs

Fertility & Reproduction, 2023
Nowadays, blastocyst biopsy is widely used in preimplantation genetic tests (PGTs), especially in preimplantation genetic testing for aneuploidy (PGT-A).
Ling Chi
doaj   +1 more source

Preimplantation genetic testing for aneuploidy and chromosomal structural rearrangement: A summary of a nationwide study by the Japan Society of Obstetrics and Gynecology

Reproductive Medicine and Biology, 2023
Purpose The Japan Society of Obstetrics and Gynecology conducted a nationwide clinical study to evaluate the pregnancy outcomes of preimplantation genetic testing for aneuploidy or chromosomal structural rearrangement (PGT‐A/SR).
Takeshi Iwasa, Akira Kuwahara, Toshiyuki Takeshita, Yuka Taniguchi, Mikio Mikami, Minoru Irahara   +5 more
doaj   +1 more source

Debate 5: All Women with Recurrent Implantation Failure Should Be Offered PGT-A Motion For – Author: Tristan Hardy; Motion Against – Author: Richard Legro

Fertility & Reproduction, 2023
Motion: For Preimplantation genetic testing for aneuploidy (PGT-A) remains one of the most controversial aspects of reproductive medicine. The benefits of deselection of embryos using PGT-A must be considered according to the clinical situation. Although
Tristan Hardy, Richard Legro
doaj   +1 more source

Could PGT-A pick up true abnormalities that have clinical relevance? Retrospective analysis of 1043 embryos

Taiwanese Journal of Obstetrics & Gynecology, 2020
Objective: To determine whether preimplantation genetic testing for aneuploidy (PGT-A) could pick up true abnormalities that have clinical relevance.
Yung-Liang Liu, Tzu-Ning Yu, Peng-Hui Wang, Chii-Ruey Tzeng, Ching-Hui Chen, Chi-Huang Chen   +5 more
doaj   +1 more source

Cost-effectiveness of preimplantation genetic testing for aneuploidy for fresh donor oocyte cycles

F&S Reports, 2021
Objective: To determine whether in vitro fertilization (IVF) with preimplantation genetic testing for aneuploidy (PGT-A) is cost effective to achieve a live birth compared with IVF alone in fresh donor oocyte cycles.
Maria Facadio Antero, M.D., Bhuchitra Singh, M.D., M.P.H, M.S., Apoorva Pradhan, B.A.M.S., M.P.H., Megan Gornet, M.D., William G. Kearns, Ph.D., Valerie Baker, M.D., M.P.P., Mindy S. Christianson, M.D.   +6 more
doaj   +1 more source

Preimplantation genetic testing for aneuploidy (PGT-A)—finally revealed

Journal of Assisted Reproduction and Genetics, 2020
Natural fecundity of women decreases gradually and more rapidly after age 37 years. This decrease is accompanied by rising aneuploidy rates of pregnancies and can also be observed in products of conception of spontaneous abortions [1]. These observations lead to the hypothesis that transferring only euploid embryos in association with in vitro ...
Raoul, Orvieto, Norbert, Gleicher
openaire   +3 more sources