Increased telomere attrition following renal transplantation: impact of anti-metabolite therapy [PDF]
, 2016 Background: The uremic milieu exposes chronic kidney disease (CKD) patients to premature ageing processes. The impact of renal replacement therapy (dialysis and renal transplantation [RTx]) or immunosuppressive treatment regimens on ageing biomarkers has
Bárány, Peter +13 more
core +1 more source
An aging evaluation of the bearing performances of glass fiber composite laminate in salt spray fog environment [PDF]
, 2019 The aim of the present paper is to assess the bearing performance evolution of pinned, glass-composite laminates due to environmental aging in salt-spray fog tests.
Bruzzaniti P. G. +4 more
core +1 more source
Environmental and genetic predictors of human cardiovascular ageing
Nature Communications, 2023 Cardiovascular ageing is a process that begins early in life and leads to a progressive change in structure and decline in function due to accumulated damage across diverse cell types, tissues and organs contributing to multi-morbidity.
Mit Shah +17 more
doaj +1 more source
Land Assembly for Housing Developments [PDF]
, 1934 The ability to identify premature arterial stiffening is of considerable value in the prevention of cardiovascular diseases. The “ageing index” (AGI), which is calculated from the second derivative photoplethysmographic (SDPPG) waveform, has been used as
Kalju Meigas +5 more
core +3 more sources
Rehabilitation: The health strategy of the 21st century. [PDF]
, 2017 There is strong evidence that population ageing and the epidemiological transition to a higher incidence of chronic, non-communicable diseases will continue to profoundly impact societies worldwide, putting more pressure on healthcare systems to respond ...
Bickenbach, Jerome +3 more
core +4 more sources
A fast ethanol assay to detect seed deterioration [PDF]
, 2012 The most common way to test seed quality is to use a simple and reliable but time- and space-consuming germination test. In this paper we present a fast and simple method to analyse cabbage seed deterioration by measuring ethanol production from ...
Buckley, W.T. +5 more
core +2 more sources
Hutchinson-Gilford progeria syndrome with severe calcific aortic valve stenosis
Annals of Pediatric Cardiology, 2011 Hutchinson-Gilford progeria syndrome (HGPS) is a rare premature aging syndrome that results from mutation in the Laminin A gene. This case report of a 12-year-old girl with HGPS is presented for the rarity of the syndrome and the classical clinical ...
Natesh B Hanumanthappa +3 more
doaj +1 more source
MicroRNAs as Mediators of the Ageing Process. [PDF]
, 2016 Published onlineReviewHuman ageing is a complex and integrated gradual deterioration of cellular processes. There are nine major hallmarks of ageing, that include changes in DNA repair and DNA damage response, telomere shortening, changes in control over
Harries, LW
core +1 more source
Evaluating the Role of p38 MAPK in the Accelerated Cell Senescence of Werner Syndrome Fibroblasts
Pharmaceuticals, 2016 Progeroid syndromes show features of accelerated ageing and are used as models for human ageing, of which Werner syndrome (WS) is one of the most widely studied.
Terence Davis +4 more
doaj +1 more source
Role of NF-κB in Ageing and Age-Related Diseases: Lessons from Genetically Modified Mouse Models
Cells, 2021 Ageing is a complex process, induced by multifaceted interaction of genetic, epigenetic, and environmental factors. It is manifested by a decline in the physiological functions of organisms and associated to the development of age-related chronic ...
Verónica A. García-García +3 more
doaj +1 more source