General anesthesia does not have persistent effects on attention in rodents [PDF]
, 2019 Background: Studies in animals have shown that general anesthesia can cause persistent spatial memory impairment, but the influence of anesthetics on other cognitive functions is unclear.
Amanda G. Nelson +8 more
core +2 more sources
Antisense oligonucleotide induction of progerin in human myogenic cells. [PDF]
PLoS ONE, 2014 We sought to use splice-switching antisense oligonucleotides to produce a model of accelerated ageing by enhancing expression of progerin, translated from a mis-spliced lamin A gene (LMNA) transcript in human myogenic cells. The progerin transcript (LMNA
Yue-Bei Luo +6 more
doaj +1 more source
Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism [PDF]
, 2018 C.L.-O. is supported by grants from the European Union (ERC-2016-ADG, DeAge); Ministerio de Economía y Competitividad (MINECO/FEDER: SAF2014-52413-R and SAF2017-87655-R); Instituto de Salud Carlos III (RTICC); Progeria Research Foundation (PRF2016-66 ...
Bárcena Fernández, Clea +11 more
core +3 more sources
ON RADIATION-INDUCED AGING: ACCELERATED OR PREMATURE AGING
Radiation Protection Dosimetry, 2022 Abstract The concept of radiation-induced aging is revisited from the viewpoint of a mathematical model. The effect of radiation on carcinogenesis is treated based on the Armitage–Doll multi-stage theory. The formula obtained for cancer incidence rate indicates that radiation dose can be explained in terms of time.
Takahiro Wada +2 more
openaire +2 more sources
Premature and accelerated ageing: HIV or HAART?
Frontiers in Genetics, 2013 Highly Active Anti-Retroviral Therapy (HAART) has significantly increased life expectancy of the HIV-positive population. Nevertheless, the average lifespan of HIV patients remains shorter compared to uninfected individuals.
Reuben Luke Smith +4 more
doaj +1 more source
Recognising the ageing face: the role of age in face processing [PDF]
, 1998 The effects of age-induced changes on face recognition were investigated as a means of exploring the role of age in the encoding of new facial memories. The ability of participants to recognise each of six previously learnt faces was tested with versions
George, Patricia A, Hole, Graham J
core +1 more source
Success and Development of Older Workers as a Challenge to Higher Education
Высшее образование в России, 2021 The article implements an attempt to present the success of older workers in the conditions of the sporting paradigm and the formation of eco-thinking in organizations.
I. B. Durakova, E. V. Mayer
doaj +1 more source
Microwave-assisted synthesis of a MK2 inhibitor by Suzuki-Miyaura coupling for study in Werner syndrome cells [PDF]
, 2015 Microwave-assisted Suzuki-Miyaura cross-coupling reactions have been employed towards the synthesis of three different MAPKAPK2 (MK2) inhibitors to study accelerated aging in Werner syndrome (WS) cells, including the cross-coupling of a 2-chloroquinoline
Bagley, Mark C +5 more
core +3 more sources
A Comparative Study on the Influence of DC/DC-Converter Induced High Frequency Current Ripple on Lithium-Ion Batteries [PDF]
, 2019 Modern battery energy systems are key enablers of the conversion of our energy and mobility sector towards renewability. Most of the time, their batteries are connected to power electronics that induce high frequency current ripple on the batteries that ...
Korth Pereira Ferraz, Pablo +1 more
core +1 more source
Anti-Ageing Effects of Sonchus oleraceus L. (pūhā) Leaf Extracts on H2O2-Induced Cell Senescence
Molecules, 2015 Antioxidants protect against damage from free radicals and are believed to slow the ageing process. Previously, we have reported the high antioxidant activity of 70% methanolic Sonchus oleraceus L. (Asteraceae) leaf extracts.
Zong-Quan Ou +2 more
doaj +1 more source