Results 111 to 120 of about 21,624 (243)

The transformer gene controls sexual development in Drosophila suzukii

Insect Science, EarlyView.
The transformer gene plays a key role in the genetic pathway for sexual development in Drosophila suzukii Abstract The genetic network of sex determination in the model organism Drosophila melanogaster was investigated in great detail. Such knowledge not only advances our understanding of the evolution and regulation of sexual dimorphism in insects ...
Ying Yan, Jing Zhao, Jonas Schwirz, Cristina Borghesi, Conghui Liu, Bo Liu, Wanqiang Qian, Fanghao Wan, Marc F. Schetelig   +8 more
wiley   +1 more source

Genetic engineering for SIT application: a fruit fly‐focused review

Insect Science, EarlyView.
Abstract Sterile insect technique (SIT) has become a key component of efficient pest control. Fruit fly pests from the Drosophilidae and Tephritidae families pose a substantial and overwhelmingly increasing threat to the agricultural industry, aggravated by climate change and globalization among other contributors.
Serafima Davydova, Danheng Yu, Angela Meccariello   +2 more
wiley   +1 more source

Slow Transit Constipation: Pathophysiological Perspectives and Management Updates

Journal of Digestive Diseases, EarlyView.
Slow transit constipation (STC) is a complex neuromuscular disorder driven by interstitial cells of Cajal (ICCs) loss and enteric neuropathy. Diagnosis relies on objective transit testing while excluding pelvic floor dysfunction. Management follows a stepwise, phenotype‐driven approach, progressing from conventional laxatives to emerging targeted ...
Athanasios Syllaios, Stavros P. Papadakos, Alexandros Ioannou, Maximos Frountzas, Dimosthenis Michelakis, Dimitrios Patsouras, Spyridon Dritsas, Manousos‐Georgios Pramateftakis, Dimitrios Schizas   +8 more
wiley   +1 more source

GnRH agonist for protection against ovarian toxicity during chemotherapy for early breast cancer:the Anglo Celtic Group OPTION trial [PDF]

, 2017
Background Chemotherapy-induced premature ovarian insufficiency (POI) impacts fertility and other aspects of women’s health. The OPTION trial tested whether administration of a gonadotropin-releasing hormone agonist during chemotherapy for early breast ...
Anderson, Anderson, Anderson, Ataya, Badawy, Coates, Del Mastro, Demeestere, Dewailly, Early Breast Cancer Trialists’ Collaborative Group, Elgindy, Elgindy, ESHRE Guideline Group on, Gerber, Harlow, Lambertini, Meirow, Moore, Morgan, Munster, Oktay, Partridge, Partridge, Su, Swain, Wilson, Zhang   +26 more
core   +3 more sources

Premature Ovarian Insufficiency: An Adolescent Series

Journal of Pediatric and Adolescent Gynecology, 2017
To study the presentation and causes of premature ovarian insufficiency (POI) in adolescents.Retrospective notes review.Tertiary referral outpatient clinic for pediatric and adolescent gynecology.Adolescents with POI.Standard POI evaluation.Age and clinical symptoms at presentation, causative factors for POI, if identified.We identified 22 girls with ...
Chaloutsou, K., Aggelidis, P., Pampanos, A., Theochari, E., Michala, L.   +4 more
openaire   +3 more sources

Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders

Andrology, EarlyView.
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret, Aaran H. Patel, Elisabeth Daniels, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Premature ovarian insufficiency: a syndrome or diagnosis

Репродуктивная эндокринология, 2017
The article presents modern views on the etiology, pathogenesis, diagnosis and management of premature ovarian insufficiency (POI) – syndrome which is heterogeneous in the etiology and pathogenesis and has a significant negative impact not only on the ...
Т. Ф Татарчук, Н. В. Косей, Т. Н. Тутченко   +2 more
doaj   +1 more source

Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions

Clinical Endocrinology, EarlyView.
ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley   +1 more source

The potential of follicle-stimulating hormone peptide-modified triptolide-loaded nanoparticles to induce a mouse model of premature ovarian insufficiency

International Journal of Nanomedicine, 2015
Xiu-Ying Chen,1–3 Wu-Lian Chen,4 Min Ma,1–3 Chao Gu,1,2 Xi-Rong Xiao,1,2 Bin Li1,2 1Obstetrics and Gynecology Hospital, Fudan University, 2Department of Obstetrics and Gynecology of Shanghai Medical College, Fudan University, 3Shanghai Key ...
Chen XY, Chen WL, Ma M, Gu C, Xiao XR, Li B   +5 more
doaj  

Lifestyle Management in Menopause: A Systematic Review of Women With Premature Ovarian Insufficiency

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Premature ovarian insufficiency (POI), the loss of ovarian function before age 40, increases the risk of cardiovascular disease, low bone mineral density, dementia and psychological distress. Lifestyle interventions reduce chronic disease risk in other populations and, with hormone therapy, may improve health outcomes in POI.
Ladan Yeganeh, Nathalie Vermeulen, Carolyn Ee, Helena Teede, Amanda J. Vincent   +4 more
wiley   +1 more source