Results 71 to 80 of about 66,942 (274)

Prenatal exposure to adverse life events and autism and autistic‐like traits in children in the Norwegian Mother, Father and Child Cohort Study (MoBa)

JCPP Advances
Background Mothers' experience of adverse life events (ALEs, e.g., divorce, bereavement, injury) during pregnancy has been linked with neurodevelopmental conditions like autism, and related traits like social communication difficulties and repetitive ...
Aleksandra Kanina, Arvid Sjölander, Miriam I. Martini, Agnieszka Butwicka, Henrik Larsson, Amanda M. Hughes, Márta K. Radó, Mark J. Taylor, Alexandra Havdahl, Helga Ask, Mina A. Rosenqvist   +10 more
doaj   +1 more source

Impact of chronodisruption during primate pregnancy on the maternal and newborn temperature rhythms. [PDF]

PLoS ONE, 2013
Disruption of the maternal environment during pregnancy is a key contributor to offspring diseases that develop in adult life. To explore the impact of chronodisruption during pregnancy in primates, we exposed pregnant capuchin monkeys to constant light (
María Serón-Ferré, María Luisa Forcelledo, Claudia Torres-Farfan, Francisco J Valenzuela, Auristela Rojas, Marcela Vergara, Pedro P Rojas-Garcia, Monica P Recabarren, Guillermo J Valenzuela   +8 more
doaj   +1 more source

Aisha Bano - The Role of KCNQ (Kv7) Potassium Channels in Schizophrenia Deficits [PDF]

, 2013
For years, studies have been conducted to treat the positive and negative symptoms and cognitive deficits of schizophrenia; it has allowed to treat the positive symptoms through regulation of dopaminergic neurons and dopamine pathways; however, we still ...
Bano, Aisha
core   +1 more source

Reading hominin life history in fossil bones and teeth: methods to test hypotheses regarding its evolution

Biological Reviews, EarlyView.
ABSTRACT Human life history is derived compared to that of our closest living relatives, the great apes. It has been suggested that these derived traits are causally related to aspects of our ecology, social behaviour and cognitive abilities. However, resolving this requires that we know the evolutionary trajectory of our distinctive pattern of growth,
Paola Cerrito, Judith M. Burkart, Carel van Schaik   +2 more
wiley   +1 more source

Inhibition of BET proteins modulates amyloid-beta accumulation and cognitive performance in middle-aged mice prenatally exposed to maternal immune activation

Frontiers in Molecular Neuroscience
IntroductionGiven the complex etiological basis of Alzheimer’s disease (AD), it is reasonable to hypothesize that neuronal dysfunction and death result from the interplay of numerous factors, both genetic and environmental.
Marta Matuszewska, Anna Wilkaniec, Magdalena Gąssowska-Dobrowolska, Magdalena Cieślik, Gabriela Olech-Kochańczyk, Ewelina Pałasz, Elżbieta Gawinek, Marcin Strawski, Grzegorz A. Czapski   +8 more
doaj   +1 more source

Paradoxical Effects of a Cytokine and an Anticonvulsant Strengthen the Epigenetic/Enzymatic Avenue for Autism Research

Frontiers in Cellular Neuroscience, 2020
Maternal exposure to the valproate short-chain fatty acid (SCFA) during pregnancy is known to possibly induce autism spectrum disorders (ASDs) in the offspring.
D. G. Béroule, D. G. Béroule
doaj   +1 more source

Pesticide Contamination in the Hair of Children From Colonia San Juan, a Rural Community in Paraguay

Drug Testing and Analysis, EarlyView.
Hair analysis in children from a rural community in Paraguay reveals exposure to organophosphates, pyrethroids, neonicotinoids, fungicides, herbicides, and endocrine disruptors, highlighting the urgent need for stricter environmental protections and preventive health measures. ABSTRACT Chronic exposure to pesticides can cause carcinogenic, reproductive,
Stela Benitez Leite, Alba Iglesias‐Gonzalez, Mirta Noemí Mesquita, María Luisa Macchi, Robin Mesnage, Brice M. R. Appenzeller   +5 more
wiley   +1 more source

A procedure for DNA methylation assessment in osteoporosis-related gene promoters of umbilical cord blood: A study on the Prospective Epidemiological Research Studies in Iran (PERSIAN) birth cohort [PDF]

BioImpacts
Introduction: It is believed that DNA methylation can modify disease susceptibility in response to environmental factors as early as the perinatal period.
Sadegh Baradaran Mahdavi, Seyed Morteza Javadirad, Mahsa Rafieian, Parnian Poursafa, Vajihe Azimian Zavareh, Seyede Shahrbanoo Daniali, Motahar Heidari-Beni, Masoomeh Goodarzi-Khoigani, Babak Vahdatpour, Hossein Mirhendi, Roya Kelishadi   +10 more
doaj   +1 more source

Pathogenesis and potential therapeutic targets of trichorhinophalangeal syndrome; lessons obtained from animal studies

Developmental Dynamics, EarlyView.
Abstract Trichorhinophalangeal syndrome (TRPS) is a rare genetic disease inherited in an autosomal dominant manner. It occurs in 1 in 100,000 people globally and is caused by several types of mutations of the TRPS1 gene. Since the first human patient was reported in 1966, typical and atypical pathologies, disease courses, and treatment case ...
Naoya Saeki, Rinna Kanai, Sayuri Tatsuta, Shinichi Kawaguchi, Masatsune Itoh, Shinsuke Ohba, Makoto Abe   +6 more
wiley   +1 more source

Prenatal Insecticide Exposures and Birth Weight and Length among an Urban Minority Cohort [PDF]

, 2004
We reported previously that insecticide exposures were widespread among minority women in New York City during pregnancy and that levels of the organophosphate chlorpyrifos in umbilical cord plasma were inversely associated with birth weight and length ...
Andria Reyes, Dana B. Barr, David E. Camann, Deliang Tang, Diurka Diaz, Frederica P. Perera, Howard F. Andrews, Jessica Dietrich, Lori A. Hoepner, Patrick L. Kinney, Pojer R, Robin Garfinkel, Robin M. Whyatt, Virginia Rauh   +13 more
core   +2 more sources