Results 1 to 10 of about 13,213 (206)

Prenylated Flavonoids in Topical Infections and Wound Healing [PDF]

Molecules, 2022
The review presents prenylated flavonoids as potential therapeutic agents for the treatment of topical skin infections and wounds, as they can restore the balance in the wound microenvironment.
Alice Sychrová, Gabriela Škovranová, Marie Čulenová, Silvia Bittner Fialová   +3 more
doaj   +4 more sources

Elucidating the Glucokinase Activating Potentials of Naturally Occurring Prenylated Flavonoids: An Explicit Computational Approach [PDF]

Molecules, 2021
Glucokinase activators are considered as new therapeutic arsenals that bind to the allosteric activator sites of glucokinase enzymes, thereby maximizing its catalytic rate and increasing its affinity to glucose. This study was designed to identify potent
Kolade Olatubosun Faloye, Boris Davy Bekono, Emmanuel Gabriel Fakola, Marcus Durojaye Ayoola, Oyenike Idayat Bello, Oluwabukunmi Grace Olajubutu, Onikepe Deborah Owoseeni, Shafi Mahmud, Mohammed Alqarni, Ahmed Abdullah Al Awadh, Mohammed Merae Alshahrani, Ahmad J. Obaidullah   +11 more
doaj   +2 more sources

Phytochemistry and pharmacology of natural prenylated flavonoids. [PDF]

Arch Pharm Res, 2023
Prenylated flavonoids are a special kind of flavonoid derivative possessing one or more prenyl groups in the parent nucleus of the flavonoid. The presence of the prenyl side chain enriched the structural diversity of flavonoids and increased their bioactivity and bioavailability. Prenylated flavonoids show a wide range of biological activities, such as
Lv HW, Wang QL, Luo M, Zhu MD, Liang HM, Li WJ, Cai H, Zhou ZB, Wang H, Tong SQ, Li XN.   +10 more
europepmc   +3 more sources

Stable Isotope Dilution Analysis of the Major Prenylated Flavonoids Found in Beer, Hop Tea, and Hops [PDF]

Frontiers in Nutrition, 2020
Prenylated flavonoids from hops (Humulus lupulus) have become of interest in recent years due to a range of bioactivities. The potential health benefits of prenylated flavonoids include anti-cancerous activities and treatment of the metabolic syndrome ...
Lance Buckett, Simone Schinko, Corinna Urmann, Corinna Urmann, Herbert Riepl, Herbert Riepl, Michael Rychlik   +6 more
doaj   +2 more sources

Beer Phenolic Composition of Simple Phenols, Prenylated Flavonoids and Alkylresorcinols [PDF]

Molecules, 2020
Beer is a fermented beverage with beneficial phenolic compounds and is widely consumed worldwide. The current study aimed to describe the content of three families of phenolic compounds with relevant biological activities: prenylated flavonoids (from ...
Anna Boronat, Natalia Soldevila-Domenech, Jose Rodríguez-Morató, Miriam Martínez-Huélamo, Rosa M. Lamuela-Raventós, Rafael de la Torre   +5 more
doaj   +2 more sources

Prenylated Flavonoids with Selective Toxicity against Human Cancers. [PDF]

Int J Mol Sci, 2023
The antiproliferative activity of xanthohumol (1), a major prenylated chalcone naturally occurring in hops, and its aurone type derivative (Z)-6,4′-dihydroxy-4-methoxy-7-prenylaurone (2) were investigated. Both flavonoids, as well as cisplatin as a reference anticancer drug, were tested in vivo against ten human cancer cell lines (breast cancer (MCF-7,
Tronina T, Bartmańska A, Popłoński J, Rychlicka M, Sordon S, Filip-Psurska B, Milczarek M, Wietrzyk J, Huszcza E.   +8 more
europepmc   +3 more sources

Targeted Isolation of Prenylated Flavonoids from Paulownia tomentosa Fruit Extracts via AI-Guided Workflow Integrating LC-UV-HRMS/MS [PDF]

Metabolites
Objectives: This study presents a versatile, AI-guided workflow for the targeted isolation and characterization of prenylated flavonoids from Paulownia tomentosa (Thunb.) Steud. (Paulowniaceae). Methods: The approach integrates established extraction and
Tomas Rypar, Lenka Molcanova, Barbora Valkova, Ema Hromadkova, Christoph Bueschl, Bernhard Seidl, Karel Smejkal, Rainer Schuhmacher   +7 more
doaj   +2 more sources

Estrogenic Prenylated Flavonoids in Sophora flavescens. [PDF]

Genes (Basel)
Sophora flavescens is a medicinal herb distributed widely in Japan and it has been used to treat various diseases and symptoms. To explore its pharmacological use, we examined the estrogenic activity of four prenylated flavonoids, namely kurarinone, kushenols A and I, and sophoraflavanone G, which are characterized by the lavandulyl group at position 8
Nishi K, Imamura I, Hoashi K, Kiyama R, Mitsuiki S.   +4 more
europepmc   +3 more sources

Prenylated Flavonoids from the Roots of Tephrosia rhodesica. [PDF]

J Nat Prod, 2020
NMReDATA for compound 1-5, and FIDs for all compounds in the publication "Prenylated Flavonoids from the roots of Tephroisa rhodesica". MS and X-ray data.
Atilaw Y, Muiva-Mutisya L, Bogaerts J, Duffy S, Valkonen A, Heydenreich M, Avery VM, Rissanen K, Erdélyi M, Yenesew A.   +9 more
europepmc   +9 more sources

Synthesis of Human Phase I and Phase II Metabolites of Hop (Humulus lupulus) Prenylated Flavonoids [PDF]

Metabolites, 2022
Hop prenylated flavonoids have been investigated for their in vivo activities due to their broad spectrum of positive health effects. Previous studies on the metabolism of xanthohumol using untargeted methods have found that it is first degraded into 8 ...
Lance Buckett, Sabrina Schönberger, Veronika Spindler, Nadine Sus, Christian Schoergenhofer, Jan Frank, Oliver Frank, Michael Rychlik   +7 more
doaj   +2 more sources