Prenylated flavonoids from maclura tinctoria fruits [PDF]
Química Nova, 2013 A phytochemical investigation of Maclura tinctoria fruits yielded five flavonoids, including one prenylated flavonol (licoflavonol) and four prenylated isoflavones (wighteone, derrone, alpinum isoflavone, and 6-(2,2-dimethyl-2H-chromen-6-yl)-2-(1-hydroxy-
Sayuri de Oliveira Oyama +4 more
doaj +3 more sources
Prenylated Flavonoids of the Moraceae Family: A Comprehensive Review of Their Biological Activities [PDF]
PlantsPrenylated flavonoids (PFs) are natural flavonoids with a prenylated side chain attached to the flavonoid skeleton. They have great potential for biological activities such as anti-diabetic, anti-cancer, antimicrobial, antioxidant, anti-inflammatory ...
Jaime Morante-Carriel +8 more
doaj +2 more sources
Immunotoxicity and Anti-Inflammatory Characterizations of Prenylated Flavonoids—The Lipophilic 7-O-Terpenylated Wogonin [PDF]
Life, 2022 Wogonin, one of the exceptional bioactive flavonoids found abundant in the roots of Huang-Qin (Scutellaria baicalensis Georgi), is a popular health-preserving Chinese medicine. The therapeutic applications can be expanded by improving its bioavailability.
Jin-Yi Wu +6 more
doaj +2 more sources
Extraction Behavior and Quantitative Profiling of Prenylated Flavonoids from Hops (Humulus lupulus L.) Under Varying Solvent Polarity, Temperature, and Cryogenic Pretreatment [PDF]
MoleculesPrenylated flavonoids from hops (Humulus lupulus L.) represent a distinctive class of bioactive compounds with notable antioxidant and health-promoting properties.
Nora Haring +2 more
doaj +2 more sources
Prenylated flavonoids from Sophora flavescens inhibit mushroom tyrosinase activity and modulate melanogenesis in murine melanoma cells and zebrafish [PDF]
Frontiers in PharmacologyBackground:Sophora flavescens, a traditional Chinese medicine for treating conditions associated with abnormal skin pigmentation, contains flavonoids with inhibitory effects on tyrosinase.
Fenling Fan +8 more
doaj +2 more sources
Molecular features of prenylated (iso)flavonoids from Fabaceae in relation to their potential NorA inhibition in Staphylococcus aureus [PDF]
Frontiers in PharmacologyBackgroundThe overexpression of the NorA efflux pump is known to be an important factor in the antimicrobial resistance mechanism of Staphylococcus aureus. Therefore, NorA inhibition can help disarm this pathogen and tackle antimicrobial resistance.
Marina Ika Irianti +5 more
doaj +2 more sources
Tuning aromatic cage occupancy in prenyltransferases enables selective and efficient production of rare c-prenylated flavonoids [PDF]
Nature CommunicationsC-prenylated flavonoids possess notable pharmaceutical potential, but their production is hindered by the challenging selective prenylation of their unstable polyphenolic cores. Natural prenyltransferases offer a direct route but suffer from low activity
Ruiying Qiu +15 more
doaj +2 more sources
Linking Global Antioxidant Assays with Targeted HPLC Profiling of Prenylated Flavonoids in Humulus lupulus L. Extracts Obtained by Accelerated Solvent Extraction [PDF]
MoleculesAccelerated solvent extraction (ASE) is widely used for recovering bioactive compounds from hops; however, the extent to which global antioxidant assays reflect changes in molecular composition remains unclear.
Nora Haring +2 more
doaj +2 more sources
Highly Cancer Selective Antiproliferative Activity of Natural Prenylated Flavonoids [PDF]
Molecules, 2018 Xanthohumol (XN) and four minor hops prenylflavonoids: α,β-dihydroxanthohumol (2HXN), isoxanthohumol (IXN), 8-prenylnaringenin (8PN), and 6-prenylnaringenin (6PN), were tested for antiproliferative activity towards human cancer and normal cell ...
Agnieszka Bartmańska +5 more
doaj +2 more sources
Efficient and Selective Extraction of Prenylated Flavonoids from Sophora flavescens Using Ultrasound-Assisted Hydrophobic Ionic Liquid and Characterization of Extraction Mechanism [PDF]
MoleculesAs a secondary metabolite with vigorous pharmacological activity (antitumor), prenylated flavonoids in Sophora flavescens (PFS) have great potential to be transformed into lead compounds. Its extraction has attracted more and more attention. Conventional
Shasha Kong +5 more
doaj +2 more sources