The ubiK protein is an accessory factor necessary for bacterial Ubiquinone (UQ) biosynthesis and forms a complex with the UQ biogenesis factor UbiJ [PDF]
Ubiquinone (UQ), also referred to as coenzyme Q, is a widespread lipophilic molecule in both prokaryotes and eukaryotes in which it primarily acts as an electron carrier.
Aussel, Laurent +7 more
core +1 more source
Fast‐twitch muscles are less susceptible to disuse atrophy, activate the mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway, and increase protein synthesis under prolonged muscle disuse conditions.
Munehiro Uda +3 more
doaj +1 more source
Post‐translational prenylations, found in eukaryotic primary metabolites and bacterial secondary metabolites, play crucial roles in biomolecular interactions.
Azusa Miyata +2 more
doaj +1 more source
The indole-diterpene paxilline is an abundant secondary metabolite synthesized by Penicillium paxilli. In total, 21 genes have been identified at the PAX locus of which six have been previously confirmed to have a functional role in paxilline ...
Emily J. Parker +13 more
doaj +1 more source
Binding, lateral diffusion and exchange are fundamental dynamic processes involved in protein association with cellular membranes. In this study, we developed numerical simulations of lateral diffusion and exchange of fluorophores in membranes with ...
Daniel A Beard +10 more
core +1 more source
Catalytic enantioselective synthesis of quaternary carbon stereocentres. [PDF]
Quaternary carbon stereocentres-carbon atoms to which four distinct carbon substituents are attached-are common features of molecules found in nature. However, before recent advances in chemical catalysis, there were few methods of constructing single ...
Overman, Larry E, Quasdorf, Kyle W
core
Prenylation of camphene. A carbocationic route to isosantalene and its derivatives [PDF]
Azizur-Rahman, +20 more
core +1 more source
Systems biology strategy for drug potentiating through drug repurposing:bisphosphonates beyond osteoporosis treatment [PDF]
Goltsov, Alexey +2 more
core +2 more sources
Pre-loading of chlorophyll synthase with tetraprenyl diphosphate is an obligatory step in chlorophyll biosynthesis [PDF]
Oster, Ulrike +4 more
core +1 more source
Case Report: Clinical application of an <i>in vitro</i> prenylation assay in the diagnosis of an early-onset case of mevalonate kinase deficiency harbouring a novel <i>MVK</i> variant. [PDF]
Burleigh A +7 more
europepmc +1 more source

