Results 91 to 100 of about 3,925 (172)
Altering the Regiospecificity of C6 Indole Prenyltransferase Enzymes Towards Drug Development [PDF]
, 2019 Prenyltransferase (PT) biocatalysts are late-stage tailoring enzymes that modify natural products. PTs catalyze the attachment of prenyl moieties to natural product acceptors using pyrophosphate donors.
Aoun, Ahmed R
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Engineering the Prenyltransferase Domain of a Bifunctional Assembly-Line Terpene Synthase
Copalyl diphosphate (CPP) synthase from Penicillium verruculosum (PvCPS) is a bifunctional diterpene synthase with both prenyltransferase and class II cyclase activities.
Samuel A. Eaton (11525272) +3 more
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The SQ and RR templates of aromatic prenyltransferase.
, 2014 The cartoon figures on the left represent the structure of aromatic prenyltransferase, which exhibited the largest difference in TM-score between the RR and SQ templates, and those in the middle present the SQ and RR template structures. In these figures,
George Chikenji (632461) +2 more
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, 2014 The cis-prenyltransferase gene LLA66 (Lilium longiflorum anther-66), the first prenyltransferase to be identified in the tapetum and microspores, was selected from a suppression subtractive cDNA library during microspore development in the anther of L ...
Wang, C.S. +4 more
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, 2022 In a previous study, it was shown that the protein encoded by the gene B318L of African swine fever virus (ASFV) is a trans-prenyltransferase that catalyzesin vitro the condensation of farnesyl diphosphate and isopentenyl diphosphate to synthesize ...
Viñuela, Eladio +3 more
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Analysis of prenyltransferase gene expression in Pseudo-nitzschia multiseries
, 2019 Domoic acid is a potent neurotoxin produced by the genus Pseudo-nitzschia. It is responsible for causing amnesic shellfish poisoning, a condition capable of devastating marine wildlife and humans with severe neurological complications once ingested. Much
Brenden Jiang
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UBIAD1 mutation alters a mitochondrial prenyltransferase to cause Schnyder corneal dystrophy.
PLoS ONE, 2010 BackgroundMutations in a novel gene, UBIAD1, were recently found to cause the autosomal dominant eye disease Schnyder corneal dystrophy (SCD). SCD is characterized by an abnormal deposition of cholesterol and phospholipids in the cornea resulting in ...
Michael L Nickerson +20 more
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, 2015 (A) Effect of statins on MK-4 conversion activity in MG63 cells. (B) Effect of bisphosphonates on MK-4 conversion activity in MG63 cells. Values not sharing a common letter in each group are significantly different (Tukey–Kramer HSD-test): P < 0.05 ...
Naoko Okuda (724165) +10 more
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Applications of substrate analogues for studies of prenyltransferase enzymes.
, 2010 University of Minnesota Ph.D. dissertation. April 2010. Major: Chemistry. Advisor: Dr. Mark D. Distefano. 1 computer file (PDF); xxii, 184 pages.Prenyltransferase enzymes serve a variety of important biological functions from the creation of natural ...
DeGraw, Amanda Jane
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The synthesis and evaluation of natural/unnatural substrates of lepidopteran prenyltransferase
, 1997 Juvenile hormone (JH) is vital to normal insect growth and development. In the lepidopteran species of Manduca Sexta, JH consists of five different methyl epoxy-farnesoate homologs, which are produced via the terpenoid biosynthetic pathway ...
Ewing, Gregory James
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