Results 91 to 100 of about 3,663 (218)

Friedel–Crafts Alkylation of Acylphloroglucinols Catalyzed by a Fungal Indole Prenyltransferase

, 2015
Naturally occurring prenylated acylphloroglucinol derivatives are plant metabolites with diverse biological and pharmacological activities. Prenylation of acylphloroglucinols plays an important role in the formation of these intriguing natural products ...
Kang Zhou (122652), Lena Ludwig (1612957), Shu-Ming Li (1523233)   +2 more
core   +1 more source

Biological Degradation of Phthalates: From Bioremediation to Plastic Waste Valorization

ChemSusChem, Volume 19, Issue 7, 14 April 2026.
Phthalic acid isomers play a key role in the plastics industry, but pose significant environmental and health concerns. This review explores the microbial biodegradation of phthalates and their esters, focusing on bacterial enzymes, catabolic pathways, and cellular uptake mechanisms of phthalates.
Marco A. Pereyra‐Camacho, Isabel Pardo
wiley   +1 more source

Structure-based engineering increased the catalytic turnover rate of a novel phenazine prenyltransferase. [PDF]

PLoS ONE, 2012
Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto aromatic substrates in biosynthetic pathways of microbial secondary metabolites.
Georg Zocher, Orwah Saleh, Joel B Heim, Dominik A Herbst, Lutz Heide, Thilo Stehle   +5 more
doaj   +1 more source

Context‐Dependent Chemoselectivity of Aromatic C‐Methyltransferases

ChemBioChem, Volume 27, Issue 8, April 2026.
Chemoselectivity is context‐dependent: The SAM‐dependent C‐MTs SfmM2 and NapB5 from streptomycetes catalyze the C‐ and/or O‐dimethylation of aromatic substrates, including l‐tyrosine and flavonoids. C‐methylation activity requires precise substrate recognition and positioning to ensure proximity between the target carbon nucleophile and the methyl ...
Juliane Breiltgens, Ziruo Zou, Sascha Ferlaino, Jennifer N. Andexer, Michael Müller   +4 more
wiley   +1 more source

Usefulness of Prenyltransferase for Organic Synthesis: Carbon—Carbon Bond Forming Reactions by Prenyltransferases and Their Mutated Enzymes

ChemInform, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
Maki, Yuji, Nagaki, Masahiko, Nishino, Tokuzo, Koyama, Tanetoshi   +3 more
openaire   +2 more sources

Inhibition of liver prenyltransferase by citronellyl and geranyl phosphonate and phosphonylphosphate.

Journal of Lipid Research, 1985
Citronellyl- and geranylphosphonic acids and the corresponding phosphonylphosphates were made and tested as inhibitors of liver prenyltransferase. Kinetic analysis showed that citronellyl- and geranylphosphonylphosphate were powerful inhibitors of the ...
G Popják, C Hadley
doaj   +1 more source

A century of vitamin E research: The innovative journey from basic biology to synthetic bio‐manufacturing

Journal of Integrative Plant Biology, Volume 68, Issue 4, Page 985-1012, April 2026.
For a century, Vitamin E has been studied for its health benefits. This review traces its journey from basic biological discovery, and the recent identification of its link to chlorophyll degradation, to the modern era of sustainable microbial manufacturing, highlighting the innovative technologies that define its future production.
Ruiqi Zhang, Yuqing Ren, Yuehe Zhao, Hongyan Zheng, Yanzhong Luo, Yuan Liu, Lei Wang, Lan Zhang   +7 more
wiley   +1 more source

The SQ and RR templates of aromatic prenyltransferase.

, 2014
The cartoon figures on the left represent the structure of aromatic prenyltransferase, which exhibited the largest difference in TM-score between the RR and SQ templates, and those in the middle present the SQ and RR template structures. In these figures,
George Chikenji (632461), Shintaro Minami (632459), Kengo Sawada (632460)   +2 more
core   +1 more source

A Pangenome Framework Reveals Conserved Pathogenicity‐Associated Biosynthetic Gene Clusters in Fusarium equiseti, a Root Rot Pathogen of Panax notoginseng

Molecular Plant Pathology, Volume 27, Issue 4, April 2026.
Integrating pangenome and infection‐stage transcriptome analyses with CRISPR/Cas9 genetics identifies conserved secondary metabolite biosynthetic gene clusters, including an ICS–NRPS and a siderophore pathway, as key determinants of Fusarium equiseti P26 pathogenicity on Panax notoginseng.
Xuping Zhang, Xiang Li, Xiaojun Li, Chao Peng, Weiguang Wang   +4 more
wiley   +1 more source

Marine-Derived Prenyltransferases

MarineMedicine
The biochemical characteristics and structural features of prenyltransferases (PTs) continue to be elucidated, revealing their significant potential as biocatalysts for the enzymatic synthesis of novel drug lead compounds. This paper comprehensively reviews marine-derived PTs, outlining the current research progress and status for each enzyme type, and
Fuhao Liu, Wenxue Wang, Changfei Li, Yue Zhang, Chuanteng Ma, Qian Che, Tianjiao Zhu, Dehai Li   +7 more
openaire   +1 more source