Results 81 to 90 of about 3,960 (214)

Measurement of the α-Secondary Kinetic Isotope Effect for a Prenyltransferase by MALDI Mass Spectrometry

, 2016
Measurement of the α-Secondary Kinetic Isotope Effect for a Prenyltransferase by MALDI Mass ...
Valerie A. Weller (3004026), Mark D. Distefano (559344)   +1 more
core   +1 more source

Genetic architecture of phenological, morphological, and phytochemical traits in Cannabis landraces

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Despite its long history of cultivation and diverse applications, Cannabis sativa remains underexplored at the genomic level, particularly in landrace populations that harbor untapped genetic diversity. In this study, we investigated the genetic architecture of 145 Iranian cannabis landrace accessions, including both male and female plants ...
Mehdi Babaei, Davoud Torkamaneh
wiley   +1 more source

African Swine Fever Virus trans-Prenyltransferase [PDF]

Journal of Biological Chemistry, 1997
The present study describes the characterization of an African swine fever virus gene homologous to prenyltransferases. The gene, designated B318L, is located within the EcoRI B fragment in the central region of the virus genome, and encodes a polypeptide with a predicted molecular weight of 35,904.
Alejo, Alí, Yáñez, Rafael J., Rodríguez, Javier M., Viñuela, Eladio, Salas Falgueras, María Luisa   +4 more
openaire   +3 more sources

cDNA cloning of a prenyltransferase from the medicinal plant Hypericum perforatum [PDF]

, 2009
Das Johanniskraut (Hypericum perforatum L.) ist eine alte Heilpflanze, deren Extrakte in der antidepressiven Therapie zum Einsatz kommen. Der Hauptinhaltsstoff ist das polyprenylierte bizyklische Acylphloroglucinol-Derivat Hyperforin.
Kühle, Susanne
core   +1 more source

Deciphering the properties and reaction mechanism of anhydromevalonate phosphate decarboxylase, a prenylated flavin mononucleotide‐dependent enzyme in the archaeal mevalonate pathway

The FEBS Journal, Volume 293, Issue 11, Page 3303-3319, June 2026.
Characterization of anhydromevalonate phosphate decarboxylase, the UbiD‐family decarboxylase involved in the archaeal mevalonate pathway, was conducted. The enzyme is responsible for the biosynthesis of isoprenoids, such as archaeal membrane lipids, respiratory quinones, and dolichols.
Rino Ishikawa, Natsumi Matsushima, Soma Ishimine, Honoka Nakamoto, Hajime Hayakawa, Yoko Yasuno, Tetsuro Shinada, Hiroshi Kawaide, Tomokazu Ito, Hisashi Hemmi   +9 more
wiley   +1 more source

Constitutive and inducible oleoresin defenses share genetic architectures and mechanisms in Pinus taeda

New Phytologist, Volume 250, Issue 5, Page 2966-2987, June 2026.
Summary The oleoresin defense system of loblolly pine (Pinus taeda) protects trees from insects and pathogens and is an important source of renewable biofuels and chemicals, but the genetic basis of oleoresin production is poorly understood. We characterized the genetic architecture of oleoresin flow, resin canal number, stem wood terpene content, and ...
Mallory M. Morgan, Jared Westbrook, Christopher Dervinis, Tania Quesada, Salvador Gezan, Robert Sykes, Timothy S. Johnson, Gabriela Madrid, Matthew Lane, Alice Townsend, Thomas A. Colquhoun, John M. Davis, Daniel Jacobson, Gary F. Peter   +13 more
wiley   +1 more source

Friedel–Crafts Alkylation of Acylphloroglucinols Catalyzed by a Fungal Indole Prenyltransferase

, 2015
Naturally occurring prenylated acylphloroglucinol derivatives are plant metabolites with diverse biological and pharmacological activities. Prenylation of acylphloroglucinols plays an important role in the formation of these intriguing natural products ...
Kang Zhou (122652), Lena Ludwig (1612957), Shu-Ming Li (1523233)   +2 more
core   +1 more source

Structural and functional insights into TBC1D17 highlight the importance of the previously uncharacterized Rab‐binding domain

Protein Science, Volume 35, Issue 5, May 2026.
Abstract TBC (Tre2/Bub2/Cdc16) domain‐containing proteins constitute the widespread family of GTPase‐activating proteins (GAPs). They interact with the Rab superfamily of small GTPases, stimulate GTP hydrolysis, and regulate vesicle trafficking. TBC1D17, involved in Shiga toxin trafficking, autophagy and glucose metabolism regulation, constitutes an ...
Dominika Nielipińska, Marta Orlikowska, Maciej Nielipiński, Bartosz Sekuła, Katarzyna M. Błażewska, Edyta Gendaszewska‐Darmach, Agnieszka J. Pietrzyk‐Brzezińska   +6 more
wiley   +1 more source

Regulation of protein prenyltransferase in central neurons

Communicative & Integrative Biology, 2009
Geranylgeranyltransferase I (GGT) is a protein prenyltransferase that mediates lipid modification of some proteins such as Rho family small GTPases. Since the activation of Rho GTPases mediates tumorgenesis and metastasis, GGT has become an attractive target for anti-tumor drug design. Although GGT is extensively expressed in the brain, the function of
Xiu-Ping, Zhou, Zhen-Ge, Luo
openaire   +2 more sources

Structure and Mechanism of PhdC, a Prenylated‐Flavin Maturase

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 5, Page 1019-1029, May 2026.
ABSTRACT Prenylated flavin mononucleotide (prFMN) is a modified flavin cofactor required by the UbiD family of (de)carboxylase enzymes. While the reduced prFMNH2 form is produced by the flavin prenyltransferase UbiX, the corresponding two‐electron oxidized prFMNiminium form is required to support UbiD catalysis. Thus, oxidative maturation of prFMNH2 is
Dominic R. Whittall, Henry G. Box, Karl A. P. Payne, Stephen A. Marshall, David Leys   +4 more
wiley   +1 more source