Results 71 to 80 of about 3,085 (184)

The Expressing Patterns of Opioid Peptides, Anti-opioid Peptides and Their Receptors in the Central Nervous System Are Involved in Electroacupuncture Tolerance in Goats

Frontiers in Neuroscience, 2018
To investigate dynamic processes of enkephalin (ENK), cholecystokinin octapeptide (CCK-8), orphanin FQ (OFQ) and their receptors (μ opioid receptor, MOR; CCK B type receptor, CCKBR and opioid receptor-like 1 receptor, OPRL1) in the central nerve system ...
Juan Wan, Zhengying Qiu, Zhengying Qiu, Yi Ding, Sha Nan, Mingxing Ding   +5 more
doaj   +1 more source

Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the G{alpha}q/11 pathway [PDF]

, 2002
MrgA1 and MrgC11 belong to a recently identified family of orphan G-protein coupled receptors, called mrgs (mas-related genes). They are only expressed in a specific subset of sensory neurons that are known to detect painful stimuli. However, the precise
Anderson, David J., Dong, Xinzhong, Han, Sang-Kyou, Hwang, Jong-Ik, Simon, Melvin I., Zylka, Mark J.   +5 more
core  

The role of the endogenous opioid system in modulating orthodontic‐induced neurogenic inflammation of the dental pulp: A comprehensive review of the literature

International Endodontic Journal, Volume 58, Issue 8, Page 1126-1145, August 2025.
Abstract Background Orthodontic forces may lead to neurogenic inflammation in the dental pulp by triggering the release of somatosensory neuropeptides such as Substance P (SP), Calcitonin gene‐related peptide (CGRP) and Neurokinin A (NKA). In the vast majority of patients, acute symptoms are not triggered, probably due to the control of the neurogenic ...
Javier Caviedes‐Bucheli, Nestor Rios‐Osorio, Esteban Ulate‐Rodríguez, Hernan Dario Muñoz‐Alvear, José F. Gaviño‐Orduña, P. Sebastian Ortolani‐Seltenerich, Jose F. Gomez‐Sosa, Hugo Roberto Munoz   +7 more
wiley   +1 more source

Nociceptive stimulation induces expression of Arc/Arg3.1 in the spinal cord with a preference for neurons containing enkephalin

Molecular Pain, 2010
Background In pain processing, long term synaptic changes play an important role, especially during chronic pain. The immediate early gene Arc/Arg3.1 has been widely implicated in mediating long-term plasticity in telencephalic regions, such as the ...
Kuhl Dietmar, Biesheuvel Karla, Jongen Joost LM, Hossaini Mehdi, Holstege Jan C   +4 more
doaj   +1 more source

A Comprehensive Review on LncRNAs/miRNAs‐DNMT1 Axis in Human Cancer: Mechanistic and Clinical Application

Journal of Cellular and Molecular Medicine, Volume 29, Issue 10, May 2025.
ABSTRACT Cancer constitutes a significant public health concern, and addressing the challenge of cancer holds paramount importance and requires immediate attention. Epigenetic alterations, encompassing DNA methylation, have emerged as pivotal contributors to the development of diverse cancer types.
Seyed Mohsen Aghaei‐Zarch, Ali Esmaeili, Saeid Bagheri‐Mohammadi   +2 more
wiley   +1 more source

Neural differentiation of the human neuroblastoma cell line IMR32 induces production of a thyrotropin-releasing hormone-like peptide [PDF]

, 1994
The human neuroblastoma cell line IMR32 produces and secretes substantial amounts of TRH-immunoreactivity (TRH-IR) as measured with radioimmunoassay (RIA) using the nonspecific antiserum 4319.
Greef, W.J. (W.) de, Klootwijk, W. (Willem), Linkels, E., Rondeel, J.M.M. (Jan), Visser, T.J. (Theo)   +4 more
core   +1 more source

Electroacupuncture Enhances Preproenkephalin mRNA Expression in Rostral Ventrolateral Medulla of Rats [PDF]

The FASEB Journal, 2009
Electroacupuncture (EA) causes prolonged suppression of reflex elevations in blood pressure for at least 80 min in anesthetized preparations. Since the opioid system may play a role in prolonged inhibition of neuronal activity in rVLM, we postulated that EA increases preproenkephalin (PPE) mRNA for prolonged ...
Min, Li, Stephanie C, Tjen-A-Looi, John C, Longhurst   +2 more
openaire   +2 more sources

Food-associated cues alter forebrain functional connectivity as assessed with immediate early gene and proenkephalin expression [PDF]

, 2007
Background Cues predictive of food availability are powerful modulators of appetite as well as food-seeking and ingestive behaviors. The neurobiological underpinnings of these conditioned responses are not well understood.
Craig A Schiltz, Quentin Z Bremer, Charles F Landry, Ann E Kelley, EA Finkelstein, JO Hill, HR Berthoud, KC Berridge, CE Cornell, IC Fedoroff, EL Gibson, A Jansen, PJ Rogers, EC Hinton, KS LaBar, WK Simmons, T Tuomisto, FS Arana, ML Pelchat, CM Gordon, WD Killgore, C Meyer, SL Mitchell, S Pecina, JN Roemmich, F Ango, KW Roche, JC Tu, JP Yuan, S Chowdhury, N Plath, EM Rial Verde, JD Shepherd, K Anggadiredja, VP Bakshi, R Ciccocioppo, AE Kelley, X Liu, M Zhang, M Zhang, M Zhang, M Zhang, M Zhang, P Salin, GR Uhl, JF Guzowski, S Malkani, K Van Keuren-Jensen, Y Yasoshima, BM Forman, B Lin, LJ Vanderschuren, CA Schiltz, BE Schroeder, BE Schroeder, A Kiss, AC DeVries, CA Schiltz, JL Valdes, JL Valdes, GD Petrovich, GD Petrovich, GD Petrovich, GD Petrovich, PC Holland, HP Weingarten, E Zamble, N Pecoraro, CL Pickens, MP Saddoris, G Schoenbaum, G Schoenbaum, MG Shuler, R Ito, JS Han, PC Holland, J Radulovic, AR McIntosh, E Coutureau, LE Mello, LE Mello, F Morrison, JW Rudy, R Ito, SB Floresco, RA Fuchs, R Ito, JA Parkinson, AL Jongen-Relo, CT Tai, I Weiner, F Mora, ET Rolls, GC Harris, SC Woods, J DeFalco, F Morl, SM Ferguson, S Miyachi, JM Uslaner, JM Uslaner, AM Arabia, S Berretta, K Campbell, HB Parthasarathy, H Steiner, MJ Will, S Narayanan, PD Skoubis, AE Kelley, AE Kelley, AS Levine, S Pecina, MM Nieto, D Borsook, I Mocchetti, F Tang, GR Uhl, GR Uhl, MD Hayward, MD Hayward, GA Lucas, MW Feltenstein, B Goddard, L Lu, CA Schiltz, SL Haberny, JD Berke, JF Guzowski, JF Guzowski, N Ramanan, D Barrett, HP Nair, CA Schiltz, G Paxinos   +134 more
core   +2 more sources

Rethinking the external globus pallidus and information flow in cortico‐basal ganglia‐thalamic circuits

European Journal of Neuroscience, Volume 60, Issue 9, Page 6129-6144, November 2024.
The GPe regulates information flow in cortico‐basal ganglia‐thalamic circuits. This nucleus relays ascending and descending signals and serves as a central hub within the CBGT network. Abstract For decades, the external globus pallidus (GPe) has been viewed as a passive way‐station in the indirect pathway of the cortico‐basal ganglia‐thalamic (CBGT ...
Cristina Giossi, Jonathan E. Rubin, Aryn Gittis, Timothy Verstynen, Catalina Vich   +4 more
wiley   +1 more source

Physiological properties of enkephalin-containing neurons in the spinal dorsal horn visualized by expression of green fluorescent protein in BAC transgenic mice

BMC Neuroscience, 2011
Background Enkephalins are endogenous opiates that are assumed to modulate nociceptive information by mediating synaptic transmission in the central nervous system, including the spinal dorsal horn. Results To develop a new tool for the identification of
Kofuji Takefumi, Tsuda Masayuki, Fukushima Teruyuki, Hori Yuuichi   +3 more
doaj   +1 more source