Results 101 to 110 of about 1,511,062 (337)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Keeping Research Data Safe 2: Final Report [PDF]
, 2010 The first Keeping Research Data Safe study funded by JISC made a major contribution to understanding of long-term preservation costs for research data by developing a cost model and indentifying cost variables for preserving research data in UK ...
Beagrie, N, Lavoie, B, Woollard, M
core
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Does Targeting a Designated Area Crowd out the other Preservation Programs’ Efforts? [PDF]
Maryland has introduced a number of land preservation programs over the past 40 years to permanently preserve resource lands. Although new programs can increase the number of acres being preserved, they might have unintended impact on land preservation ...
Liu, Xiangping, Lynch, Lori
core +1 more source
Addressing data management training needs: a practice based approach from the UK [PDF]
, 2012 In this paper, we describe the current challenges to the effective management and preservation of research data in UK universities, and the response provided by the JISC Managing Research Data programme. This paper will discuss, inter alia, the findings
Davidson, J. +3 more
core
DPHEP: From Study Group to Collaboration
, 2013 The international study group on data preservation in high energy physics, DPHEP, achieved a milestone in 2012 with the publication of its eagerly anticipated large scale report, which contains a description of data preservation activities from all major
South, David M.
core +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
State-of-the-art survey of privacy-preserving data aggregation in wireless sensor networks
Tongxin xuebao, 2018 A state-of-the-art survey of privacy-preserving data aggregation techniques in wireless sensor networks was reviewed.Firstly,preliminaries were introduced,including network models,adversary models,and performance evaluation metrics.Secondly,existing ...
Xiaoying ZHANG, Hui PENG, Hong CHEN
doaj +2 more sources