Results 101 to 110 of about 1,438,161 (234)

HEP Software Foundation Community White Paper Working Group - Data and Software Preservation to Enable Reuse

open access: yes, 2018
In this chapter of the High Energy Physics Software Foundation Community Whitepaper, we discuss the current state of infrastructure, best practices, and ongoing developments in the area of data and software preservation in high energy physics.
Boehnlein, A.   +22 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Managing Research Data: Gravitational Waves [PDF]

open access: yes, 2012
The project which led to this report was funded by JISC in 2010–2011 as part of its ‘Managing Research Data’ programme, to examine the way in which Big Science data is managed, and produce any recommendations which may be appropriate. Big science data
Carozzi, T.D., Gray, N., Woan, G.
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Preservation of Data for Earth System Science- Towards a Content Standard [PDF]

open access: yes
Various remote sensing agencies of the world have created a data rich environment for research and applications over the last three decades. Especially over the last decade, the volume and variety of data useful for Earth system science have increased ...
Duerr, Ruth   +2 more
core   +1 more source

A digital library for the University of York [PDF]

open access: yes, 2008
The University of York has recently launched a project to set-up a multimedia repository service for the University?s research resources, both those produced out of and used within research.
Allinson, Julie
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Publications and Observational Data in the Archive of Konkoly Observatory [PDF]

open access: yes, 2007
We present the status of ongoing digital preservation projects at Konkoly Observatory. The electronic IBVS, the Communications/Mitteilungen series and observational data digitization are discussed, with some open ...
Holl, András
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

State-of-the-art survey of privacy-preserving data aggregation in wireless sensor networks

open access: yesTongxin xuebao, 2018
A state-of-the-art survey of privacy-preserving data aggregation techniques in wireless sensor networks was reviewed.Firstly,preliminaries were introduced,including network models,adversary models,and performance evaluation metrics.Secondly,existing ...
Xiaoying ZHANG, Hui PENG, Hong CHEN
doaj   +2 more sources

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