Results 141 to 150 of about 66,976 (313)
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
, 2014 The invention relates to a preservative composition comprising a polyamidoamine polymer dissolved or dispersed in an aqueous solvent and/or in an organic solvent, and its use for coating wood, paper, stone and lithoid construction materials (for ex-ample
Bergamonti, Laura +4 more
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Oxygenated Preservation Solutions for Organ Preservation
Transplantation, 2018 Narendra R, Battula, Kenneth A, Andreoni
openaire +4 more sources
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
, 2014 Matteo Sacchi, Edoardo Villani, Paolo NucciUniversity Eye Clinic, San Giuseppe Hospital, University of Milan, Milan, ItalyWe read with interest the article entitled "Effects of tafluprost treatment for 3 years in patients with normal-tension ...
Villani E, Nucci P, Sacchi M
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EFSA JournalFollowing a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the application for renewal of authorisation of sodium bisulphate (SBS) as a feed additive for all terrestrial animal species (category:
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +24 more
doaj +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
, 2018 Mario A Economou,1 Helene Kolstad Laukeland,2,3 Iwona Grabska-Liberek,4 Jean-François Rouland5 1Anterior Segment Department, St Erik’s Eye Hospital, Karolinska Institute, Stockholm, Sweden; 2Department of Ophthalmology, University Hospital,
Rouland JF +3 more
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