Results 101 to 110 of about 1,776 (189)
Frontiers in Medicine, 2015 Objectives. A phase I pretargeted radioimmunotherapy trial (EudractCT 200800603096) was designed in patients with metastatic lung cancer expressing carcinoembryonic antigen (CEA) to optimize bispecific antibody and labelled peptide doses, as well as the ...
Caroline eBodet-Milin +23 more
doaj +1 more source
Pretargeted delivery of PEG-coated drug carriers to breast tumors using multivalent, bispecific antibody against polyethylene glycol and HER2 [PDF]
, 2019 Pretargeting is an increasingly explored strategy to improve nanoparticle targeting, in which pretargeting molecules that bind both selected epitopes on target cells and nanocarriers are first administered, followed by the drug-loaded nanocarriers ...
Jacobs, Timothy M +6 more
core +2 more sources
Engineered Cells as a Test Platform for Radiohaptens in Pretargeted Imaging and Radioimmunotherapy Applications. [PDF]
Bioconjug Chem, 2021 Dacek MM +16 more
europepmc +1 more source
Synthesis, Characterization and Biological Studies of Technetium-99m and Rhenium-188 Peptides
, 2017 Radiopharmaceuticals are very powerful diagnostic tools for evaluation of a host of medical conditions. These drugs are labeled with radioactive isotopes, which are utilized to create pictures of areas of interest through absorption of the drug. They are
Sanders, Vanessa Anne
core +1 more source
Bioorthogonal Small Molecule Imaging Agents Allow Single-Cell Imaging of MET [PDF]
, 2013 The hepatocyte growth factor receptor (MET) is a receptor tyrosine kinase (RTK) that has emerged as an important cancer target. Consequently, a number of different inhibitors varying in specificity are currently in clinical development. However, to date,
Kim, Eunha +2 more
core +3 more sources
BIOTINYLATED AND CHELATED POLY-L-LYSINE AS EFFECTOR FOR PRETARGETING IN CANCER THERAPY AND IMAGING [PDF]
, 2017 Objective: The aim of this study was to synthesise and evaluate polylysine-based effectors for pretargeted radioimmunotherapy and imaging. These molecules can readily be size-modified and charge-modified to decrease the renal uptake of radioactivity ...
Albertsson, Per +7 more
core +1 more source
Detection of chemotherapy-induced cardiotoxicity with antimyosin pretargeted imaging [PDF]
Journal of Nuclear Cardiology, 2019 H William, Strauss, Giuliano, Mariani
openaire +2 more sources
Journal of NanobiotechnologyBackground Radiotheranostics differs from the vast majority of other cancer therapies in its capacity for simultaneous imaging and therapy, and it is becoming more widely implemented.
Hongzhang Yang +13 more
doaj +1 more source
Unambiguous detection of atherosclerosis by pretargeted molecular imaging
, 2019 Peer ...
Fernández-Barahona, Irene +4 more
openaire +1 more source