Results 81 to 90 of about 1,776 (189)

High-Sensitivity Fluorometry to Resolve Ion Channel Conformational Dynamics [PDF]

open access: yes, 2018
Fluorescent labels offer the capability to follow conformational dynamics of membrane proteins, but signal detection in such recordings is inherently difficult to achieve in a cell membrane and lacks sufficient time resolution to follow physiologically ...
Pless, Stephan Alexander, Wulf, Matthias
core   +2 more sources

Self‐Assembly of Noncanonical Peptides: A New Frontier in Cancer Therapeutics and Beyond

open access: yesMacromolecular Bioscience, Volume 25, Issue 8, August 2025.
Representative examples of noncanonical peptide assemblies in anticancer therapeutics, biomaterials, regenerative medicine, molecular imaging, and catalysis are discussed, highlighting enzyme‐instructed self‐assembly as a valuable approach for constructing biomimetic and bioinspired materials that bridge the interface between biological systems and ...
Lin Bai, Meihui Yi, Bing Xu
wiley   +1 more source

Therapeutic Applications of Pretargeting

open access: yesPharmaceutics, 2019
Targeted therapies, such as radioimmunotherapy (RIT), present a promising treatment option for the eradication of tumor lesions. RIT has shown promising results especially for hematologic malignancies, but the therapeutic efficacy is limited by ...
Marjolein Verhoeven   +2 more
doaj   +1 more source

Predictive Nomogram for Recurrence following Surgery for Nonmetastatic Renal Cell Cancer with Tumor Thrombus [PDF]

open access: yes, 2017
Purpose Following surgery for nonmetastatic renal cell carcinoma with tumor thrombus the risk of recurrence is significant but variable among patients.
Abel, E. Jason   +10 more
core   +1 more source

A Spatially Distributed Microneedle System for Bioorthogonal T Cell‐Guided Cancer Therapy

open access: yesAdvanced Science, Volume 12, Issue 13, April 3, 2025.
A spatially distributed microneedle system (SDMNS) comprises two dissolving microneedles: DBCO‐αCD3/28@MNs, which activate T cells and label them with bioorthogonal groups in lymph nodes, and IP10‐Az@MNs, which label tumor cells and guide T cell migration.
Lanya Li   +11 more
wiley   +1 more source

Excitation functions for (p,x) reactions of niobium in the energy range of E$_{\text{p}}$ = 40-90 MeV [PDF]

open access: yes, 2018
A stack of thin Nb foils was irradiated with the 100 MeV proton beam at Los Alamos National Laboratory's Isotope Production Facility, to investigate the $^{93}$Nb(p,4n)$^{90}$Mo nuclear reaction as a monitor for intermediate energy proton experiments and
Bernstein, Lee A.   +7 more
core   +2 more sources

Exploring New Bioorthogonal Catalysts: Scaffold Diversity in Catalysis for Chemical Biology

open access: yesAdvanced Science, Volume 12, Issue 9, March 6, 2025.
This review provides a comprehensive and timely overview of the recent advances in scaffolded bioorthogonal catalysts. It discusses the design principles, mechanisms of action, and distinct features of these novel catalysts. Besides, it also emphasizes the potential impact of these unique catalysts on advancing bioorthogonal chemistry and offers ...
Yan Zhang   +8 more
wiley   +1 more source

Nano/genetically engineered cells for immunotherapy

open access: yesBMEMat, Volume 3, Issue 1, March 2025.
Multiple types of cells including immune cells, red blood cells, platelets, stem cells, β cells, adipocytes, and bacteria can function as cell‐derived drug carriers or genetically engineered cellular drugs according to their unique biological properties and functions for the immunotherapy of tumor, autoimmune diseases, inflammation, infectious disease,
Jingrui Shen, Yang Zhou, Lichen Yin
wiley   +1 more source

CD11b-Based Pre-Targeted SPECT/CT Imaging Allows for the Detection of Inflammation in Aortic Aneurysm

open access: yesJournal of Inflammation Research, 2022
Xiaonan Zhou,1,2,* Kai Zhu,1,2,* Yiqiu Zhang,3– 5,* Yang Ming,1,2 Dai Shi,3– 5 Hui Tan,3– 5 Bitao Xiang,1,2 Shichao Zhu,1,2 Dengfeng Cheng,3– 5 Hao Lai,1,2 Chunsheng Wang,1,2 Guobing Liu3– 5 1Department of Cardiac Surgery, Zhongshan Hospital,
Zhou X   +11 more
doaj  

Focal Spot, Summer 1999 [PDF]

open access: yes, 1999
https://digitalcommons.wustl.edu/focal_spot_archives/1082/thumbnail ...

core   +1 more source

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