Experimental Evidence That Blood Parasite Infection Affects Incubation Patterns in a Cavity-Nesting Songbird. [PDF]
Integr ZoolChronic blood parasite infections in wild birds can affect their incubation behavior. In pied flycatchers, females with reduced parasite infections incubated for longer than control females. Despite behavioral changes, no immediate effects on fitness were observed.
García-Del Río M +5 more
europepmc +2 more sources
KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro. [PDF]
, 2014 Preventing relapses of Plasmodium vivax malaria through a radical cure depends on use of the 8-aminoquinoline primaquine, which is associated with safety and compliance issues.
Borboa, Rachel +25 more
core +1 more source
Primaquine in vivax malaria: an update and review on management issues
Malaria Journal, 2011 Primaquine was officially licensed as an anti-malarial drug by the FDA in 1952. It has remained the only FDA licensed drug capable of clearing the intra-hepatic schizonts and hypnozoites of Plasmodium vivax.
Fernando Deepika +2 more
doaj +1 more source
Clinical and parasitological response to oral chloroquine and primaquine in uncomplicated human Plasmodium knowlesi infections [PDF]
, 2013 Background: Plasmodium knowlesi is a cause of symptomatic and potentially fatal infections in humans. There are no studies assessing the detailed parasitological response to treatment of knowlesi malaria infections in man and whether antimalarial ...
Cox Singh, Janet +6 more
core +1 more source
Malaria Journal, 2018 Background The preventive treatment of Plasmodium vivax relapse recommended by the World Health Organization is primaquine at a dose of 15 mg/day for 14 days, except for malaria cases from Asia and Oceania.
Audrey Valdes +11 more
doaj +1 more source
Use of primaquine and glucose-6-phosphate dehydrogenase deficiency testing: Divergent policies and practices in malaria endemic countries. [PDF]
PLoS Neglected Tropical Diseases, 2018 Primaquine is the only available antimalarial drug that kills dormant liver stages of Plasmodium vivax and Plasmodium ovale malarias and therefore prevents their relapse ('radical cure').
Judith Recht +2 more
doaj +1 more source
Transition from endemic behavior to eradication of malaria due to combined drug therapies: an agent-model approach [PDF]
, 2019 We introduce an agent-based model describing a susceptible-infectious-susceptible (SIS) system of humans and mosquitoes to predict malaria epidemiological scenarios in realistic biological conditions.
Lind, Pedro G. +3 more
core +2 more sources
Case Series of Primaquine-Induced Haemolytic Events in Controlled Trials with G6PD Screening
Pathogens, 2023 Primaquine for radical cure of Plasmodium vivax malaria poses a potentially life-threatening risk of haemolysis in G6PD-deficient patients. Herein, we review five events of acute haemolytic anaemia following the administration of primaquine in four ...
Ayleen Kosasih +16 more
doaj +1 more source
Combined DNA extraction and antibody elution from filter papers for the assessment of malaria transmission intensity in epidemiological studies. [PDF]
, 2013 BACKGROUND: Informing and evaluating malaria control efforts relies on knowledge of local transmission dynamics. Serological and molecular tools have demonstrated great sensitivity to quantify transmission intensity in low endemic settings where the ...
Baidjoe, Amrish +13 more
core +3 more sources
Prospective evaluation of BDProbeTec strand displacement amplification (SDA) system for diagnosis of tuberculosis in non-respiratory and respiratory samples. [PDF]
, 2004 Nucleic acid amplification techniques (NAATs) have been demonstrated to make significant improvements in the diagnosis of tuberculosis (TB), particularly in the time to diagnosis and the diagnosis of smear-negative TB. The BD ProbeTec strand displacement
Billington, OJ +7 more
core +2 more sources