Results 31 to 40 of about 14,994 (162)

Malaria in Nonimmune Travelers [PDF]

, 1994
Background: With the current increase of international travel to tropical endemic areas, the incidence of malaria being imported into nonendemic countries has increased significantly.
Jelinek, Thomas, Löscher, Thomas, Nothdurft, H. D.   +2 more
core   +1 more source

Hybrid Molecules as Efficient Drugs against Multidrug‐Resistant Malaria Parasites

ChemMedChem, Volume 20, Issue 11, June 2, 2025.
Among hybrid molecules currently developed as antimalarial drug candidates, emoquine‐1 exhibits high activity against all the multidrug‐resistant Plasmodium strains tested up to now, including artemisinin‐resistant quiescent parasites, critical parameters for promising antimalarial drugs. It is also curative in mouse malaria.
Anne Robert, Lucie Paloque, Jean‐Michel Augereau, Flore Nardella, Michel Nguyen, Bernard Meunier, Françoise Benoit‐Vical   +6 more
wiley   +1 more source

Taking Drugs to Help Others [PDF]

, 2016
Every day the news shows us provoking stories about what's going on in the world, about events which raise moral questions and problems. In Philosophers Take On the World a team of philosophers get to grips with a variety of these controversial issues ...
Douglas, Thomas
core  

Declining Burden of Plasmodium vivax in a Population in Northwestern Thailand from 1995 to 2016 before Comprehensive Primaquine Prescription for Radical Cure. [PDF]

, 2020
All Plasmodium cases have declined over the last decade in northwestern Thailand along the Myanmar border. During this time, Plasmodium vivax has replaced Plasmodium falciparum as the dominant species. The decline in P.
Carrara, Verena I, Charunwatthana, Prakaykaew, Chu, Cindy S, McGready, Rose, Nosten, François, Parker, Daniel M, Proux, Stéphane   +6 more
core  

Integrated Phenotypic and Genotypic Approaches for Accurate Diagnosis of G6PD Deficiency: Implications for Drug Safety in Thailand

Pharmacology Research &Perspectives, Volume 13, Issue 3, June 2025.
ABSTRACT Glucose‐6‐phosphate dehydrogenase (G6PD) deficiency holds critical health concerns, particularly due to its association with drug‐induced hemolysis triggered by medications such as antimalarials. This condition poses significant risks in malaria‐endemic regions where the prevalence and genetic diversity of G6PD deficiency further complicate ...
Natnicha Pengsuk, Kamonwan Chamchoy, Chatnapa Duangdee, Jantawan Satayarak, Naowarat Saralamba, Wang Nguitragool, Usa Boonyuen   +6 more
wiley   +1 more source

Safety and Efficacy of Adding a Single Low Dose of Primaquine to the Treatment of Adult Patients With Plasmodium falciparum Malaria in Senegal, to Reduce Gametocyte Carriage: A Randomized Controlled Trial. [PDF]

, 2017
Introduction: More information is needed about the safety of low-dose primaquine in populations where G6PD deficiency is common. Methods: Adults with Plasmodium falciparum malaria were randomized to receive 1 of 3 artemisinin combination therapies (ACTs)
Fall, Fatou B, Faye, Babacar, Faye, Babacar T, Gaye, Oumar, Greenwood, Brian, Milligan, Paul, Ndiaye, Jean Louis, Ndiaye, Magatte, Poirot, Eugenie, Sow, Doudou, Sylla, Khadime, Tine, Roger C, Wang, Duolao   +12 more
core   +2 more sources

Pneumocystis jirovecii Pneumonia in Cancer Patients, a Lethal Yet Fully Preventable Disease: Insights From a Tertiary Cancer Center in East India

Asia-Pacific Journal of Clinical Oncology, Volume 21, Issue 3, Page 319-327, June 2025.
Age and history of lung radiotherapy are overlooked risk factors for Pneumocystis jirovecii pneumonia (PCP) in cancer patients. Prophylaxis appeared to be fully effective. 21‐day mortality rate in the PCP group was 35.4%. Hematologic malignancy and lung cancer patients are at highest risk for mortality.
S. Chatterji, V. Franchi, A. J. Konnakottu, P. Das, S. Mukherjee, S. Bhattacharya, A. Chatterjee   +6 more
wiley   +1 more source

A reiterative method for calculating the early bactericidal activity of antituberculosis drugs.

, 2002
Studies of early bactericidal activity (EBA) are important in the rapid evaluation of new antituberculosis drugs. Historically, these have concentrated on the log fall in the viable count in sputum during the first 48 hours of therapy.
Charalambous, Bambos M, Gillespie, Stephen H, Gosling, Roland D   +2 more
core   +1 more source

High prevalence of antibodies to human herpesvirus 8 in relatives of patients with classic Kaposi's sarcoma from Sardinia [PDF]

, 1998
A survey for antibodies to a recombinant small viral capsid antigen (sVCA) of human herpesvirus type 8 (HHV‐8) was conducted in Sardinia, one of the world's highest incidence areas for classic Kaposi's sarcoma (KS). Prevalence of antibodies to HHV‐8 sVCA
Angeloni, Antonio, Cerimele, Decio, Cottoni, Francesca Maria Giovanna, Faggioni, Alberto, Heston, Lee, Lin, Su-Fang, Masala, Maria Vittoria, Miller, George, Rigsby, Michael, Sirianni, Maria Caterina, Sun, Ren, Uccini, Stefania   +11 more
core   +1 more source

Accidental Alkyl Nitrite (Poppers) Ingestion in a 37‐Year‐Old Patient: A Case Report

Clinical Case Reports, Volume 13, Issue 5, May 2025.
ABSTRACT This case demonstrates severe methemoglobinemia in a male patient following accidental ingestion of alkyl nitrites (“Poppers”). Prompt recognition and treatment with methylene blue ensured rapid recovery. Clinicians must consider this condition in patients with unexplained cyanosis and discordant oxygen saturation.
Laurie‐Anne De Pauw, Youcef Guechi, Jessica Schwaller   +2 more
wiley   +1 more source