Results 11 to 20 of about 4,961,010 (265)

[11C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial

Nature Medicine, 2023
Primary aldosteronism (PA) due to a unilateral aldosterone-producing adenoma is a common cause of hypertension. This can be cured, or greatly improved, by adrenal surgery.
, Claudia P Cabrera, Sam O'Toole
exaly   +2 more sources

Identification of risk loci for primary aldosteronism in genome-wide association studies

Nature Communications, 2022
Detection of primary aldosteronism, the most common form of secondary arterial hypertension, is essential for targeted management and prevention of cardiovascular complications.
Edith Le Floch, Teresa Cosentino, Casper K. Larsen, Felix Beuschlein, Martin Reincke, Laurence Amar, Gian-Paolo Rossi, Kelly De Sousa, Stéphanie Baron, Sophie Chantalat, Benjamin Saintpierre, Livia Lenzini, Arthur Frouin, Isabelle Giscos-Douriez, Matthis Ferey, Alaa B. Abdellatif, Tchao Meatchi, Jean-Philippe Empana, Xavier Jouven, Christian Gieger, Melanie Waldenberger, Annette Peters, Daniele Cusi, Erika Salvi, Pierre Meneton, Mathilde Touvier, Mélanie Deschasaux, Nathalie Druesne-Pecollo, Sheerazed Boulkroun, Fabio L. Fernandes-Rosa, Jean-François Deleuze, Xavier Jeunemaitre, Maria-Christina Zennaro   +32 more
doaj   +2 more sources

The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline

Journal of Clinical Endocrinology and Metabolism, 2016
OBJECTIVE To develop clinical practice guidelines for the management of patients with primary aldosteronism. PARTICIPANTS The Task Force included a chair, selected by the Clinical Guidelines Subcommittee of the Endocrine Society, six additional experts,
Robert M Carey, Martin Reincke, Hirotaka Shibata   +2 more
exaly   +2 more sources

Subclinical primary aldosteronism [PDF]

Archives of Endocrinology and Metabolism
Primary aldosteronism (PA) is a major contributor to hypertension and cardiovascular disease. Subclinical PA, a preclinical or early manifestation of PA, has been identified in individuals with normal blood pressure and in those with mild hypertension ...
Stéfanie Parisien-La Salle, Jenifer M. Brown, Cheng Hsuan Tsai, Gregory L. Hundemer, Anand Vaidya   +4 more
doaj   +2 more sources

Occurrence of Metabolic Disorders in Bilateral Primary Aldosteronism Compared to Unilateral Primary Aldosteronism [PDF]

Diseases
Background: Metabolic syndrome (MetS) is a common comorbidity associated with hypertension that occurs more often in primary aldosteronism (PA). Our work aims to investigate the prevalence of MetS and its determinants in unilateral PA and bilateral PA ...
Chiara Grasselli, Maicol Baldini, Lucia Salvi, Grazia Vestita, Maurizio Zizzo, Davide Felaco, Maria Carolina Balli, Giulia Besutti, Aurelio Negro, Angelo Ghirarduzzi   +9 more
doaj   +2 more sources

Primary aldosteronism [PDF]

Gland Surgery, 2020
Primary aldosteronism (PA) is a common cause of secondary hypertension caused by excessive and inappropriate secretion of the hormone aldosterone from one or both adrenal glands. The prevalence of PA ranges from 10% in the general hypertensive population to 20% in resistant hypertension, yet only a small fraction of patients is diagnosed.
Sean M, Wrenn, Anand, Vaidya, Carrie C, Lubitz   +2 more
  +6 more sources

Emerging methods for subtype differentiation in primary aldosteronism. [PDF]

J Intern Med
Abstract Primary aldosteronism (PA) is a common cause of hypertension. Compared to patients with essential hypertension, untreated PA is associated with a two‐ to fourfold greater risk of cardiovascular disease, renal failure, and death. PA is caused by increased secretion of aldosterone from one adrenal gland in 30% of the patients and both adrenal ...
Ragnarsson O, Juhlin CC, Åkerström T, Dahlqvist P, Falhammar H, Hellman P.   +5 more
europepmc   +2 more sources

Screening and Diagnosis of Primary Aldosteronism in Patients Using Renin-Angiotensin System Inhibitors. [PDF]

J Clin Hypertens (Greenwich)
ABSTRACT This study investigated whether patients receiving renin‐angiotensin system inhibitors (RASIs) can undergo reliable screening for primary aldosteronism (PA) without discontinuation of therapy. Consecutive patients with hypertension who underwent PA screening at our hospital between 2016 and 2024 while on RASIs were recruited.
Wang Q, Dong H, Li HW, Zou YB, Jiang XJ.
europepmc   +2 more sources

Accuracy of Gallium-68 Pentixafor Positron Emission Tomography–Computed Tomography for Subtyping Diagnosis of Primary Aldosteronism

JAMA Network Open, 2023
This diagnostic study investigates the accuracy of gallium-68 pentixafor positron emission tomography–computed tomography vs adrenal vein sampling in subtyping diagnosis of primary aldosteronism.
Jinbo Hu, Tingting Xu, Hang Shen, Ying Song, Jun Yang, Aipin Zhang, Haoyuan Ding, Naiguo Xing, Zhuoyuan Li, L. Qiu, Linqiang Ma, Yi Yang, Zheng-ping Feng, Z. Du, Wenwen He, Yue Sun, Jun Cai, Qifu Li, Yue Chen, Shumin Yang   +19 more
semanticscholar   +1 more source

Mutation in Aldosterone Producing Adenoma [PDF]

Endocrinology and Metabolism, 2017
Discoveries of somatic mutations permit the recognition of subtypes of aldosterone-producing adenomas (APAs) with distinct clinical presentations and pathological features. Catenin β1 (CTNNB1) mutation in APAs has been recently described and discussed in
Jian-Jhong Wang, Kang-Yung Peng, Vin-Cent Wu, Fen-Yu Tseng, Kwan-Dun Wu   +4 more
doaj   +1 more source