Results 21 to 30 of about 4,961,010 (265)

Markers of Kidney Tubular Function Deteriorate While Those of Kidney Tubule Health Improve in Primary Aldosteronism After Targeted Treatments

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Targeted treatment with mineralocorticoid receptor antagonists (MRAs) or adrenalectomy in patients with primary aldosteronism (PA) causes a decline in estimated glomerular filtration rate; however, the associated simultaneous changes in ...
Vin‐Cent Wu, Chieh‐Kai Chan, Jeff S. Chueh, Yung‐Ming Chen, Yen‐Hung Lin, Chin‐Chen Chang, Po‐Chih Lin, Shiu‐Dong Chung   +7 more
doaj   +1 more source

The Value of Targeting CXCR4 with 68Ga-Pentixafor PET/CT for Subtyping Primary Aldosteronism.

Journal of Clinical Endocrinology and Metabolism, 2023
PURPOSE Primary aldosteronism (PA) is one of the leading causes of secondary hypertension, and its diagnostic subtyping consistently presents a clinical challenge.
Yanqing Zheng, Tingting Long, N. Peng, Mengling Zhen, Qianwen Ye, Zhen Zhang, Yao He, Zhi Chen, Yu Gan, Min Luo, Chun Xing Li, Zehao Liu, Min Guo, Min Wang, Xianghang Luo, Shuo Hu, Longfei Liu, Tiejian Jiang   +17 more
semanticscholar   +1 more source

Benefits of Surgical Over Medical Treatment for Unilateral Primary Aldosteronism

Frontiers in Endocrinology, 2022
Primary aldosteronism is the most common and modifiable form of secondary hypertension. Left untreated, primary aldosteronism leads high rates of cardiovascular, metabolic, and kidney disease.
Sumaiya Ahmed, Gregory L. Hundemer
doaj   +1 more source

Biomarkers to Guide Medical Therapy in Primary Aldosteronism.

Endocrine reviews, 2023
Primary aldosteronism (PA) is an endocrinopathy characterized by dysregulated aldosterone production that occurs despite suppression of renin and angiotensin II, and that is non-suppressible by volume and sodium loading.
G. Hundemer, A. Leung, G. Kline, Jenifer M. Brown, Adina F. Turcu, A. Vaidya   +5 more
semanticscholar   +1 more source

A Retrospective Study on the Impact of Primary Aldosteronism in Pregnancy (H.A.P.P.I. Study Group). [PDF]

Clin Endocrinol (Oxf)
ABSTRACT Objective Primary aldosteronism (PA) is a common cause of hypertension in young women. However, there is a paucity of data regarding its impact during pregnancy. The primary objective of this study was to describe the occurrence of hypertensive disorders of pregnancy (HDP) in PA.
Oprea D, Lefrançois F, St-Jean M, Côté AM, Roy-Lacroix MÈ, Malick M, Mallet PL, Sauvé N.   +7 more
europepmc   +2 more sources

Japan Endocrine Society clinical practice guideline for the diagnosis and management of primary aldosteronism 2021.

Endocrine journal, 2022
Primary aldosteronism (PA) is associated with higher cardiovascular morbidity and mortality rates than essential hypertension. The Japan Endocrine Society (JES) has developed an updated guideline for PA, based on the evidence, especially from Japan.
M. Naruse, T. Katabami, Hirotaka Shibata, Masakatsu Sone, Katsutoshi Takahashi, A. Tanabe, Shoichiro Izawa, T. Ichijo, M. Otsuki, M. Omura, Y. Ogawa, Y. Oki, I. Kurihara, Hiroki Kobayashi, R. Sakamoto, F. Satoh, Y. Takeda, Tomoaki Tanaka, K. Tamura, M. Tsuiki, Shigeatsu Hashimoto, T. Hasegawa, T. Yoshimoto, T. Yoneda, Koichi Yamamoto, H. Rakugi, N. Wada, A. Saiki, Y. Ohno, Tatsuya Haze   +29 more
semanticscholar   +1 more source

PRIMARY ALDOSTERONISM: CURRENT DIAGNOSTIC APPROACH

Байкальский медицинский журнал, 2022
Primary aldosteronism is characterized by aldosterone secretion that is independent of renin and angiotensin II. The deleterious effects of primary aldosteronism are mediated by excessive activation of the mineralocorticoid receptor that results in the ...
Elena S. Eniseeva
doaj   +1 more source

Primary aldosteronism: molecular medicine meets public health

Nature Reviews Nephrology, 2023
Primary aldosteronism is the most common single cause of hypertension and is potentially curable when only one adrenal gland is the culprit. The importance of primary aldosteronism to public health derives from its high prevalence but huge under ...
E. Azizan, William M. Drake, Morris J. Brown   +2 more
semanticscholar   +1 more source

Treating Primary Aldosteronism-Induced Hypertension: Novel Approaches and Future Outlooks

Endocrine reviews, 2023
Primary aldosteronism (PA) is the most common cause of secondary hypertension and is associated with increased morbidity and mortality when compared with blood pressure–matched cases of primary hypertension.
N. Mullen, James M G Curneen, Padraig T. Donlon, P. Prakash, I. Bancos, M. Gurnell, M. Dennedy   +6 more
semanticscholar   +1 more source

Cortisol Co-Secretion and Clinical Usefulness of ACTH Stimulation Test in Primary Aldosteronism: A Systematic Review and Biases in Epidemiological Studies

Frontiers in Endocrinology, 2021
The hypothalamus-pituitary-adrenal (HPA) axis plays an important role in primary aldosteronism. Aldosterone biosynthesis is regulated not only by angiotensin II in the renin-angiotensin-aldosterone system, but also by adrenocorticotropic hormone (ACTH ...
Kosuke Inoue, Kosuke Inoue, Takumi Kitamoto, Takumi Kitamoto, Yuya Tsurutani, Jun Saito, Masao Omura, Tetsuo Nishikawa   +7 more
doaj   +1 more source