Results 31 to 40 of about 13,828 (220)

A Rare Aldosterone-Producing Adenoma Detected by 68Ga-pentixafor PET-CT: A Case Report and Literature Review

Frontiers in Endocrinology, 2019
Context: Primary aldosteronism represents an important and common cause of hypertension and is characterized by autonomous aldosterone secretion that results in severe hypertension and hypokalemia.
Yunying Cui, Yushi Zhang, Jie Ding, Huiping Wang, Xiaoshen Ma, Ou Wang, Xiaoyan Chang, Hao Sun, Li Huo, Anli Tong   +9 more
doaj   +1 more source

Heightened Cardiovascular Risk in Hypertension Associated With Renin‐Independent Aldosteronism Versus Renin‐Dependent Aldosteronism: A Collaborative Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background While both renin‐dependent and renin‐independent aldosterone secretion contribute to aldosteronism, their relative associations with cardiovascular disease (CVD) risk has not been investigated.
Jinbo Hu, Hang Shen, Peiqi Huo, Jun Yang, Peter J Fuller, Kanran Wang, Yi Yang, Linqiang Ma, Qingfeng Cheng, Lilin Gong, Wenwen He, Ting Luo, Mei Mei, Yue Wang, Zhipeng Du, Rong Luo, Jun Cai, Qifu Li, Ying Song, Shumin Yang   +19 more
doaj   +1 more source

Primary Aldosteronism, Aldosterone, and Extracellular Vesicles

Endocrinology, 2021
Abstract Primary aldosteronism (PA) is an endocrine related condition leading to arterial hypertension due to inappropriately high and unregulated aldosterone concentration. Recently, a broad spectrum of PA has been recognized, which brings new challenges associated with early identification of this condition that affect renal epithelial
Cristian A Carvajal, Alejandra Tapia-Castillo, Jorge A Pérez, Carlos E Fardella   +3 more
openaire   +2 more sources

Clinical comparison and genetic analysis in pheochromocytoma with primary aldosteronism

Endocrine Journal
Pheochromocytoma is a rare form of adrenal hypertension. This study aimed to investigate the clinical characteristics and associated genetic mutations in patients with pheochromocytoma and primary aldosteronism.
Xurong Mai, Mitsuhiro Kometani, Toshiaki Kato, Ko Aiga, Shigehiro Karashima, Daisuke Aono, Seigo Konishi, Koshiro Nishimoto, Kazuyoshi Hosomichi, Atsushi Watanabe, Yuko Noda, Yoshiyu Takeda, Takashi Yoneda   +12 more
doaj   +1 more source

HCG-responsive aldosteronoma with transient secretion during pregnancy confirmed through HCG-stimulated adrenal venous sampling

Frontiers in Endocrinology, 2023
Primary aldosteronism can be regulated by the ectopic expression of G-protein coupled receptors in aldosteronomas or bilateral hyperplasias. We report a rare case of a young woman in whom 2 pregnancies were complicated by pre-eclampsia and 1 miscarriage.
Frederic Castinetti, Carole Guerin, Estelle Louiset, André Lacroix   +3 more
doaj   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Association of glucagon-like peptide-1 receptor agonists with cardiovascular and kidney outcomes in type 2 diabetic kidney transplant recipients

Cardiovascular Diabetology
Background Cardiovascular disease is a leading cause of post-transplant mortality in kidney transplant recipients (KTRs), especially those with diabetes.
Li-Chun Lin, Jui-Yi Chen, Thomas Tao-Min Huang, Vin-Cent Wu   +3 more
doaj   +1 more source

New advances in the diagnosis of primary aldosteronism

Chronic Diseases and Translational Medicine, 2020
Primary aldosteronism (PA) is a common form of endocrine hypertension. The diagnostic process of PA includes a screening test, confirmatory test, and subtype classification.
Hang Shen, Zhi-Xin Xu, Qi-Fu Li
doaj   +1 more source

Mapping CSC‐Mediated Ovarian Cancer Chemoresistance via CXCR4‐PET to Guide Precision Cisplatin Re‐Sensitization Therapy

Advanced Science, EarlyView.
CXCR4 functions as a potential cancer stem cell‐associated marker linked to chemoresistance in ovarian cancer, and an inhibitor of CXCR4, AMD3100, can enhance the cytotoxic response to cisplatin. Based on these findings, [68Ga]Ga‐Pentixafor positron emission tomography enables selective visualization of CXCR4‐high ovarian cancer, while AMD3100 combined
Lixia Feng, Simei Zhao, Zheng Wei, Wenwen Wang, Feiquan Ying, Lin Huang, Mengna Zhu, Mengqing Chen, Qiang Yang, Si Sun, Dawei Jiang, Lingling Gao, Jing Cai   +12 more
wiley   +1 more source

GLP-1 receptor agonists’ impact on cardio-renal outcomes and mortality in T2D with acute kidney disease

Nature Communications
Previous studies have explored the effects of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in reducing cardiovascular events in type 2 diabetes.
Heng-Chih Pan, Jui-Yi Chen, Hsing-Yu Chen, Fang-Yu Yeh, Chiao-Yin Sun, Thomas Tao-Min Huang, Vin-Cent Wu   +6 more
doaj   +1 more source