Results 41 to 50 of about 12,019 (221)

Primary renal potassium wasting syndrome in a juvenile domestic medium‐hair cat secondary to an atypical distal renal tubular disorder of undetermined molecular origin

Veterinary Record Case Reports, EarlyView.
Abstract Renal potassium wasting syndromes, such as Gitelman's syndrome (GS), are well documented in humans but rarely reported in veterinary medicine. This case describes a 6‐month‐old domestic medium‐hair cat presenting with chronic hypokalaemia, polyuria and polydipsia. Diagnostic evaluation revealed hypokalaemia, metabolic alkalosis, hypochloraemia
Kyle L. Granger Jr., Vivian Ojeda‐Rosenthal, Mei Lun Mui   +2 more
wiley   +1 more source

Clinical Significance of Skeletal Fat‐to‐Muscle Ratio in Idiopathic Hyperaldosteronism

Clinical Endocrinology, EarlyView.
ABSTRACT Objective The objective of this study is to evaluate the correlation between the fat‐to‐muscle ratio (FMR) and insulin resistance (IR) with aldosterone production among patients with idiopathic hyperaldosteronism (IHA). Methods Patients with primary aldosteronism were screened from those with secondary hypertension and then subtyped via ...
Yuhe Jiang, Dan Li, Cassie Chen Cao, Wenjing Feng, Ruidong Liu, Yinfei Xu, Caixia Cao   +6 more
wiley   +1 more source

The results of immunohistochemical study of antibodies to CYP11B2 in primary hyperaldosteronism

Ожирение и метаболизм, 2021
Background: Aldosterone-producing adrenocortical adenoma (APA) is responsible for the majority of cases clinically diagnosed as primary aldosteronism. Aldosterone synthase (CYP11B2) is one of the enzymes that play essential roles in aldosterone synthesis
N. Yu. Romanova, L. S. Selivanova, N. M. Platonova, D. G. Beltsevich, E. A. Troshina   +4 more
doaj   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

Activation of aldosterone secretion in primary aldosteronism [PDF]

Journal of Clinical Investigation, 1969
Angiotensin infusion evokes marked increases in aldosterone secretion in primary aldosteronism and little change in secondary aldosteronism. The low plasma renin activity of primary aldosteronism and the elevated plasma renin activity of secondary aldosteronism are thought to account for this differential response.
Sidney L. Dale, Paul C. Kahn, Richard F. Spark, James C. Melby   +3 more
openaire   +3 more sources

Primary aldosteronism with hypokalemic rhabdomyolysis: a case report and review of the literature

Journal of Medical Case Reports
Background Hypokalemic rhabdomyolysis is a rare clinical manifestation of primary aldosteronism, making its diagnosis challenging, particularly when it becomes the primary presenting symptom.
Pingan Shi, Chao Wang, Yuanjun Lyu
doaj   +1 more source

Factors Associated with Resolution of Hypertension after Adrenalectomy in Patients with Primary Aldosteronism [PDF]

Endocrinology and Metabolism, 2018
BackgroundThe aim of this study was to investigate the factors associated with resolution of hypertension after adrenalectomy in patients with primary aldosteronism.
Wann Jia Loh, Dawn Shao Ting Lim, Lih Ming Loh, Peng Chin Kek   +3 more
doaj   +1 more source

Retrospective analysis of influences of sacubitril/valsartan in patients with diabetes with poorly controlled blood pressure in Japan

Journal of Diabetes Investigation, EarlyView.
Sacubitoril/valsartan vs thiazide in patients with diabetes. ABSTRACT Aims Achieving optimal blood pressure control remains challenging, particularly for patients with diabetes. This post‐hoc study compared the efficacy and safety of switching to sacubitril/valsartan vs adding thiazide diuretics in this population.
Shun Ito, Kazuo Kobayashi, Mari Sotozawa, Kyoji Chiba, Keiichi Chin, Hideo Shimura, Toshinao Tsuge, Hiroyuki Sakai, Takayuki Furuki, Atsushi Matsuzaki, Shinichi Nakajima, Nobukazu Takada, Hareaki Yamamoto, Hiroshi Takeda, Hiromichi Wakui, Takamasa Iwasawa, Togo Aoyama, Kouichi Tamura, Masao Toyoda, Akira Kanamori   +19 more
wiley   +1 more source

Primary Aldosteronism and Ischemic Heart Disease

Frontiers in Cardiovascular Medicine, 2022
Cardiovascular disease, in particular ischemic heart disease is a major cause of morbidity and mortality worldwide. Primary aldosteronism is the leading cause of secondary hypertension, yet commonly under diagnosed, and represents a major preventable ...
Shivaraj Patil, Chaitanya Rojulpote, Aman Amanullah   +2 more
doaj   +1 more source

Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications

Experimental Physiology, EarlyView.
Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó, Luis Eduardo M. Quintas   +1 more
wiley   +1 more source