Results 41 to 50 of about 4,961,010 (265)

Different pathogenesis of glucose intolerance in two subtypes of primary aldosteronism: Aldosterone‐producing adenoma and idiopathic hyperaldosteronism

Journal of Diabetes Investigation, 2020
Aims/Introduction An increased risk of diabetes mellitus has been reported in primary aldosteronism, but the pathogenesis of glucose intolerance between the primary aldosteronism subtypes remains unclear.
Mikiko Okazaki‐Hada, Ayako Moriya, Mototsugu Nagao, Shinichi Oikawa, Izumi Fukuda, Hitoshi Sugihara   +5 more
doaj   +1 more source

Cerebro-Cardiovascular Risk, Target Organ Damage, and Treatment Outcomes in Primary Aldosteronism

Frontiers in Cardiovascular Medicine, 2022
Primary aldosteronism (PA) is the most common type of endocrine hypertension, and numerous experimental and clinical evidence have verified that prolonged exposure to excess aldosterone is responsible for an increased risk of cerebro-cardiovascular ...
Xiao Lin, Muhammad Hasnain Ehsan Ullah, Xiong Wu, Feng Xu, S. Shan, Li-Min Lei, Ling-Qing Yuan, Jun Liu   +7 more
semanticscholar   +1 more source

Strain Imaging for the Early Detection of Cardiac Remodeling and Dysfunction in Primary Aldosteronism

Diagnostics, 2022
Speckle tracking echocardiography is a novel technique to quantify cardiac function and deformation. It has been applied in a series of cardiovascular diseases for the evaluation of early cardiac impairment. We recently used this technique to investigate
Yilin Chen, Tingyan Xu, Jianzhong Xu, Limin Zhu, Dian Wang, Yan Li, Jiguang Wang   +6 more
doaj   +1 more source

Outcomes of a Specialized Clinic on Rates of Investigation and Treatment of Primary Aldosteronism.

JAMA Surgery, 2021
Importance Primary aldosteronism (PA) is one of the most common causes of secondary hypertension but remains largely unrecognized and untreated. Objective To understand the outcomes of a specialized clinic on rates of evaluation and treatment of PA in ...
Yuan-yuan Liu, J. King, G. Kline, R. Padwal, J. Pasieka, Guanmin Chen, Benny So, A. Harvey, A. Chin, A. Leung   +9 more
semanticscholar   +1 more source

Primary Aldosteronism: Where Are We Now? Where to From Here?

HYPERTENSION, 2022
Primary aldosteronism, the most common secondary form of hypertension, is thought to be present in ≈5% to 10% of hypertensive adults. However, recent studies indicate that its prevalence may be at least 3-fold higher based on the identification of renin ...
J. Funder, R. Carey
semanticscholar   +1 more source

Performance of Confirmatory Tests for Diagnosing Primary Aldosteronism: a Systematic Review and Meta-Analysis

HYPERTENSION, 2022
Background: Confirmatory tests are recommended for diagnosing primary aldosteronism, but the supporting evidence is unclear. Methods: We searched Medline, EMBASE, and the Cochrane Central Register of Controlled Trials.
A. Leung, C. Symonds, G. Hundemer, P. Ronksley, D. Lorenzetti, J. Pasieka, A. Harvey, G. Kline   +7 more
semanticscholar   +1 more source

Comparison of Echocardiographic Changes Between Surgery and Medication Treatment in Patients With Primary Aldosteronism

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Primary aldosteronism can cause cardiac dysfunction, including left ventricular hypertrophy, left ventricular diastolic dysfunction, and left atrial enlargement.
Tomomi Ueda, Yuya Tsurutani, Jun Osada, Kosuke Inoue, Yoshitomo Hoshino, Masato Ono, Kazuki Nakai, Jun Saito, Kazuhiko Yumoto, Tetsuo Nishikawa   +9 more
doaj   +1 more source

Performance of the Aldosterone-to-Renin Ratio as a Screening Test for Primary Aldosteronism: A Systematic Review and Meta-Analysis.

Journal of Clinical Endocrinology and Metabolism, 2021
CONTEXT The aldosterone-to-renin ratio (ARR) is the guideline-recommended screening test for primary aldosteronism. However, there is limited data in regard to the diagnostic performance of the ARR. OBJECTIVE To evaluate the sensitivity and specificity
A. Hung, Sumaiya Ahmed, Ankur Gupta, A. Davis, G. Kline, A. Leung, M. Ruzicka, S. Hiremath, G. Hundemer   +8 more
semanticscholar   +1 more source

Adrenocortical Causes of Hypertension

International Journal of Hypertension, 2011
Primary aldosteronism is the most common cause of secondary hypertension. In the past, screening for primary aldosteronism was offered only in patients with hypertension associated with hypokalemia.
Andreas Moraitis, Constantine Stratakis
doaj   +1 more source

Primary aldosteronism: Pathophysiological mechanisms of cell death and proliferation

Frontiers in Endocrinology, 2022
Primary aldosteronism is the most common surgically curable form of hypertension. The sporadic forms of the disorder are usually caused by aldosterone overproduction from a unilateral adrenocortical aldosterone-producing adenoma or from bilateral ...
Martina Tetti, Martina Tetti, Siyuan Gong, Franco Veglio, Martin Reincke, Tracy Ann Williams, Tracy Ann Williams   +6 more
doaj   +1 more source