Results 51 to 60 of about 23,028 (267)

GLP-1 receptor agonists’ impact on cardio-renal outcomes and mortality in T2D with acute kidney disease

Nature Communications
Previous studies have explored the effects of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in reducing cardiovascular events in type 2 diabetes.
Heng-Chih Pan, Jui-Yi Chen, Hsing-Yu Chen, Fang-Yu Yeh, Chiao-Yin Sun, Thomas Tao-Min Huang, Vin-Cent Wu   +6 more
doaj   +1 more source

Primary aldosteronism and obstructive sleep apnea: What do we know thus far?

Frontiers in Endocrinology, 2022
Both primary aldosteronism and obstructive sleep apnea are well-known causes of hypertension and contribute to increased cardiovascular morbidity and mortality independently.
Huai Heng Loh, Huai Heng Loh, Norlela Sukor   +2 more
doaj   +1 more source

Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications

Experimental Physiology, EarlyView.
Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó, Luis Eduardo M. Quintas   +1 more
wiley   +1 more source

Case report: Percutaneous adrenal arterial embolization cures resistant hypertension

Frontiers in Cardiovascular Medicine, 2022
BackgroundPrimary aldosteronism is a common cause of resistant hypertension. Patients with primary aldosteronism due to aldosterone-producing adenoma are generally treated with unilateral adrenalectomy or medical therapy.
Yaqiong Zhou, Yaqiong Zhou, Dan Wang, Dan Wang, Qiting Liu, Qiting Liu, Jixin Hou, Jixin Hou, Peijian Wang, Peijian Wang   +9 more
doaj   +1 more source

Advances in the biochemical diagnostics of primary aldosteronism: from immunoassays to steroidomics and proteomics

Frontiers in Endocrinology
Primary aldosteronism is the most common cause of secondary hypertension, yet most cases remain unrecognized and left without optimal treatment. The diagnostic inertia may be attributed to the lack of specific symptoms, insufficient awareness among ...
Alicja Szatko, Alicja Szatko, Alicja Szatko, Agata Toboła, Henrik Falhammar, Henrik Falhammar, Wojciech Zgliczyński, Piotr Glinicki, Piotr Glinicki   +8 more
doaj   +1 more source

Mass Spectrometric Measurements of 11‐Deoxycortisol, Androstenedione and Dehydroepiandrosterone Are Superior to Cortisol to Assess Selectivity of Non‐Stimulated Adrenal Vein Sampling

Clinical Endocrinology, Volume 104, Issue 1, Page 10-18, January 2026.
ABSTRACT Objective Successful adrenal venous sampling (AVS) is traditionally assessed using the ratio of cortisol in adrenal to peripheral venous plasma to calculate the selectivity index. With mass spectrometry other steroids can be simultaneously measured that may improve numbers of apparent successful sampling procedures.
Francesco Alessi, Christina Pamporaki, Mirko Peitzsch, Georgiana Constantinescu, Hanna Remde, Lydia Kürzinger, Carmina T. Fuss, Manuel Schulze, Sybille Fuld, Sradha Kotwal, Jun Yang, Martin Reincke, Felix Beuschlein, Jacques W. M. Lenders, Graeme Eisenhofer   +14 more
wiley   +1 more source

Renin-Angiotensin-Aldosterone System, Glucose Metabolism and Incident Type 2 Diabetes Mellitus: MESA. [PDF]

, 2018
Background Mechanistic studies suggest that aldosterone impairs glucose metabolism. We investigated the cross-sectional associations of aldosterone and plasma renin activity with fasting plasma glucose, insulin resistance ( IR ), β-cell function, and ...
Allison, Matthew A, Echouffo Tcheugui, Justin B, Effoe, Valery S, Golden, Sherita H, Hsueh, Willa A, Joseph, Joshua J   +5 more
core   +1 more source

A case report of hyponatremia after surgery for Conn's adenoma [PDF]

, 2017
Primary aldosteronism (PA), also known as Conn's syndrome, is a frequent cause of secondary hypertension. If PA is due to a documented unilateral adrenal adenoma, adrenalectomy is the treatment of choice.
Bardelli, Moreno, Bernardi, Stella, Carretta, Renzo, CAVRESSI, MONICA, Fabris, Bruno, FURLANIS, GIULIA, ZANDON\uc0, LORENZO   +6 more
core   +1 more source

Predicting Significant Blood Pressure Reduction Through Ambulatory Blood Pressure Monitoring in Patients With Obstructive Sleep Apnea Treated With Continuous Positive Airway Pressure

The Clinical Respiratory Journal, Volume 20, Issue 1, January 2026.
CPAP therapy induces a modest reduction in blood pressure among patients with OSA. Patients with a baseline 24‐h MAP of ≥ 96 mmHg experience greater absolute and relative reductions in all blood pressure measures after CPAP treatment than those with a lower MAP. ABSTRACT Objective Continuous positive airway pressure (CPAP) therapy for obstructive sleep
Yuanni Jiao, Hehe Zhang, Hao Wu, Xin Xi, Shuang Li, Jiang Xie   +5 more
wiley   +1 more source

Steroid metabolome analysis reveals prevalent glucocorticoid excess in primary aldosteronism [PDF]

, 2017
BACKGROUND. Adrenal aldosterone excess is the most common cause of secondary hypertension and is associated with increased cardiovascular morbidity. However, adverse metabolic risk in primary aldosteronism extends beyond hypertension, with increased ...
Adolf, Christian, Arlt, Wiebke, Asbach, Evelyn, Bancos, Irina, Beuschlein, Felix, Bidlingmaier, Martin, Biehl, Michael, Chortis, Vasileios, Deeks, Jonathan J., Deinum, Jaap, Dekkers, Tanja, Dietz, Anna S., Feuchtinger, Annette, Gilligan, Lorna C., Hahner, Stefanie, Hassan-Smith, Zaki K., Hughes, Beverly A., Keevil, Brian G., Lang, Katharina, Ludwig, Philippe, O'Neil, Donna M., Quinkler, Marcus, Rees, Dafydd Aled, Reincke, Martin, Rhayem, Yara, Riester, Anna, Shackleton, Cedric H.L., Sitch, Alice J., Tomlinson, Jeremy W., Walch, Axel K.   +29 more
core   +4 more sources