Results 61 to 70 of about 13,828 (220)

Stiff to Soft: A Protein‐Based Buffer Layer for Improving the Long‐Term Performance of Microneedle Sensors

open access: yesAdvanced Materials, Volume 38, Issue 15, 12 March 2026.
To enhance stability and long‐term biocompatibility of wearable microneedle sensors, a crosslinking‐recombination bovine serum albumin material is used as a buffer layer coated on microneedle sensors. This coating layer possesses a unique stiff‐to‐soft transition function balancing the mechanical stiffness desired for puncturing and soft required for ...
Lihao Guo   +16 more
wiley   +1 more source

Adrenal vein sampling for primary aldosteronism: a 15-year national referral center experience

open access: yesRadiology and Oncology, 2020
Adrenal vein sampling (AVS) is essential for diagnostics of primary aldosteronism, distinguishing unilateral from bilateral disease and determining treatment options. We reviewed the performance of AVS for primary aldosteronism at our center during first
Kocjan Tomaz   +5 more
doaj   +1 more source

ClC‐2 Contributes to Hypotonicity‐Induced Adrenal Aldosterone Secretion

open access: yesActa Physiologica, Volume 242, Issue 3, March 2026.
ABSTRACT Aim The zona glomerulosa (ZG) of the adrenal cortex regulates blood pressure and electrolyte homeostasis through aldosterone production. In ZG cells, potassium and angiotensin II (Ang II) trigger calcium oscillations that drive aldosterone synthesis.
Marina Volkert   +3 more
wiley   +1 more source

Dietary Sodium Reduction Reveals Aldosterone Dysregulation in Patients With Essential Hypertension

open access: yesThe Journal of Clinical Hypertension, Volume 28, Issue 3, March 2026.
ABSTRACT Dietary sodium reduction affects blood pressure (BP), the renin‐angiotensin‐aldosterone system (RAAS) and natriuretic peptides. Whether baseline levels of these hormones impact BP response to sodium reduction remains unknown. Aldosterone dysregulation relates to higher cardiovascular risk, but the relation to sodium reduction has not been ...
Camilla L. Duus   +4 more
wiley   +1 more source

Adrenal computed tomography and NP-59 usefulness for diagnosing aldosterone-producing adenomas and idiopathic hyperaldosteronism in primary hyperaldosteronism

open access: yesUrological Science, 2016
Objectives: Two major causes of primary aldosteronism are aldosterone-producing adenomas (APA) and idiopathic hyperaldosteronism (IHA). In this study, we attempted to determine the role of NP-59 in identifying APA prior to adrenalectomy, especially when ...
Ting-Po Lin   +6 more
doaj   +1 more source

Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications

open access: yesExperimental Physiology, Volume 111, Issue 3, Page 653-673, 1 March 2026.
Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó   +1 more
wiley   +1 more source

Clinical significance of parathyroid hormone in mineral and glucose metabolism disorders among patients with primary aldosteronism

open access: yesSAGE Open Medicine
Objective: To investigate the differences in mineral and glucose metabolic disorders among patients with primary aldosteronism, nonfunctional adrenal tumors, and controls. Methods: A retrospective analysis was conducted on clinical data from 578 patients,
Zhilian Sun, Wenxiu Liu
doaj   +1 more source

Gitelman and Bartter Syndrome in a Patient With Morbid Obesity: A Case Report and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT We present a case study of a 34‐year‐old man with morbid obesity and a suspected Bartter–Gitelman spectrum tubulopathy (without genetic confirmation), weighing 135 kg, and with a BMI of 42.5 kg/m2, who was referred to the metabolic and bariatric surgery department due to morbid obesity to address abnormal electrolyte levels.
Solmaz Hasani   +4 more
wiley   +1 more source

Primary aldosteronism diagnosis in the intensive care unit: resistant alkalosis and hypokalemia during severe sepsis with hyperlactatemia: a case report

open access: yesJournal of Medical Case Reports
Background Primary aldosteronism screening indications include hypertension (resistant, severe, early onset, with stroke/other comorbidities/sleep apnea), hypokalemia, adrenal incidentaloma, and primary aldosteronism first-degree relatives.
Yug Garg   +9 more
doaj   +1 more source

Clinical significance of CYP11B2 immunostaining in unilateral primary aldosteronism

open access: yesEndocrine Connections
Objective: The associations between adrenal histopathology, lateralization studies, and surgical outcomes in primary aldosteronism remain poorly characterized.
Marianna Viukari   +11 more
doaj   +1 more source

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