Aldosterone and Cardiovascular Risk Across the Lifespan
MetabolitesAldosterone excess, particularly in the context of primary aldosteronism, is associated with adverse cardiovascular outcomes. Historically considered a condition of resistant hypertension with hypokalaemia, patients with primary aldosteronism often ...
Roshan A. Ananda +2 more
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Primary Aldosteronism and Pregnancy
Kidney & Blood Pressure Research, 2020 Objective: Primary aldosteronism (PA) may present at younger age and may thus complicate pregnancy. Our aim was to identify female patients in whom PA was diagnosed after pregnancy complicated with hypertension and to analyze possible hypertension ...
Tomáš Zelinka +5 more
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Primary Aldosteronism: Novel Insights
Current Hypertension Reviews, 2020 Background: Primary aldosteronism is one of the most common causes of secondary hypertension. Patients with this endocrine syndrome are at increased cardiovascular risk, higher than hypertensive individuals with equal blood pressure levels. Objectives: The study aimed to thoroughly present and critically discuss the novel insights into the field of ...
Stavropoulos, K. +6 more
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Risk of dementia in primary aldosteronism compared with essential hypertension: a nationwide cohort study [PDF]
, 2023 Namki Hong +6 more
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Eplerenone improves kidney function and cardiac performance in obese male mice
Diabetic Medicine, Volume 43, Issue 1, January 2026.Abstract Aims Renin‐angiotensin‐aldosterone system (RAAS) activation mediates obesity‐associated cardiorenal dysfunction. Due to an incomplete understanding of the molecular mechanisms, the clinical use of RAAS antagonism in obesity‐associated cardiometabolic complications remains uncertain.
Ayman K. Banah +8 more
wiley +1 more source
Resistant arterial hypertension in a patient with adrenal incidentaloma multiple steno-obstructive vascular lesions and antiphospholipid syndrome [PDF]
, 2015 Resistant hypertension is defined as above of blood pressure (≤ 140/90 mmHg) despite therapy with three or more antihypertensive drugs of different classes at maximum tolerable doses with one bling a diuretic.
CONCISTRE, ANTONIO +8 more
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Primary aldosteronism with hypokalemic rhabdomyolysis: a case report and review of the literature
Journal of Medical Case ReportsBackground Hypokalemic rhabdomyolysis is a rare clinical manifestation of primary aldosteronism, making its diagnosis challenging, particularly when it becomes the primary presenting symptom.
Pingan Shi, Chao Wang, Yuanjun Lyu
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Factors Associated with Resolution of Hypertension after Adrenalectomy in Patients with Primary Aldosteronism [PDF]
Endocrinology and Metabolism, 2018 BackgroundThe aim of this study was to investigate the factors associated with resolution of hypertension after adrenalectomy in patients with primary aldosteronism.
Wann Jia Loh +3 more
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The results of immunohistochemical study of antibodies to CYP11B2 in primary hyperaldosteronism
Ожирение и метаболизм, 2021 Background: Aldosterone-producing adrenocortical adenoma (APA) is responsible for the majority of cases clinically diagnosed as primary aldosteronism. Aldosterone synthase (CYP11B2) is one of the enzymes that play essential roles in aldosterone synthesis
N. Yu. Romanova +4 more
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Hypertension, 2014 See related article, p 783–789 Primary aldosteronism (PA) is the most common form of secondary hypertension accounting for ≈10% of patients referred to hypertension clinics and as high as 20% of those with refractory hypertension.1 The most important causes of PA are idiopathic hyperaldosteronism (IHA), also called bilateral zona glomerulosa ...
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