Results 101 to 110 of about 95,754 (365)

The changing faces of cholangitis [version 1; referees: 2 approved]

open access: yesF1000Research, 2016
A variety of diseases are included under the umbrella term ‘cholangitis’, including hepatobiliary diseases with an autoimmune pathogenesis (such as primary sclerosing cholangitis, primary biliary cholangitis, and IgG4-associated sclerosing cholangitis ...
Sum P. Lee   +2 more
doaj   +1 more source

Hepcidin is an antibacterial, stress-inducible peptide of the biliary system. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND/AIMS: Hepcidin (gene name HAMP), an IL-6-inducible acute phase peptide with antimicrobial properties, is the key negative regulator of iron metabolism.
Pavel Strnad   +10 more
doaj   +1 more source

Prognostic value of thyroid hormone levels in patients evaluated for liver transplantation [PDF]

open access: yes, 1985
The thyroid hormones T4, T3, rT3 and TSH were assayed in 134 adult patients evaluated and accepted as potential liver transplant candidates at the Universty of Pittsburgh from March, 1981 to December, 1983.
Carter   +20 more
core   +1 more source

Primary biliary cholangitis: Diagnosis and treatment

open access: yesLiver Research, 2018
Primary biliary cholangitis (PBC) is an autoimmune disease that causes progressive destruction of the intrahepatic bile ducts. Although the pathogenesis of PBC is not completely understood, it is characterized by cholestatic inflammation resulting in a ...
Michael Chew, Christopher L. Bowlus
doaj   +1 more source

Metabolomic biomarkers are associated with mortality in patients with cirrhosis caused by primary biliary cholangitis or primary sclerosing cholangitis

open access: yesFuture Science OA, 2020
Aim: To assess the ability of signature metabolites alone, or in combination with the model for end-stage liver disease-Na (MELD-Na) score to predict mortality in patients with cirrhosis caused by primary biliary cholangitis or primary sclerosing ...
Ayse L Mindikoglu   +18 more
doaj   +1 more source

IGFBP4 is a Metric for Primary Biliary Cholangitis and Attenuates Biliary Epithelial Cell Injury. [PDF]

open access: yesLiver Int
ABSTRACT Background and Aims Immune‐mediated bile duct injury is the primary histological feature of autoimmune cholestatic liver diseases. Macrophages, the most abundant immune cell population in the liver, have been postulated to play a critical role in biliary repair. However, it is unclear whether activated macrophages interact with injured biliary
Zhou X   +12 more
europepmc   +2 more sources

Pathophysiology of primary biliary cholangitis [PDF]

open access: yesBest Practice & Research Clinical Gastroenterology, 2018
Primary biliary cholangitis is a prototypical autoimmune disease characterized by an overwhelming female predominance, a distinct clinical phenotype, and disease specific anti-mitochondrial antibodies targeted against a well-defined auto-antigen.
Aliya F, Gulamhusein   +1 more
openaire   +2 more sources

Changes in the gut microbiota of mice orally exposed to methylimidazolium ionic liquids [PDF]

open access: yes, 2020
Ionic liquids are salts used in a variety of industrial processes, and being relatively non-volatile, are proposed as environmentally-friendly replacements for existing volatile liquids.
Abdelghany, Tarek M.   +7 more
core   +2 more sources

A patient with primary biliary cholangitis, autoimmune hepatitis, and primary sclerosing cholangitis variant syndrome

open access: yesJournal of Translational Autoimmunity, 2020
Overlap between autoimmune hepatitis (AIH) and either primary biliary cholangitis (PBC) or primary sclerosing cholangitis (PSC) is not rare and has extensively been reported. We herein report the first well documented case of triple overlap.
Benedetta Terziroli Beretta-Piccoli   +6 more
doaj   +1 more source

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