Results 31 to 40 of about 95,754 (365)

Primary biliary cholangitis presenting as acute ischemic stroke: A rare association

Clinical Case Reports, 2020
Primary biliary cholangitis is associated with hyperlipidemia, but studies show that the condition does not increase cardiovascular risks. The case presents acute ischemic stroke with no underlying risk factors and subsequent new diagnosis of primary ...
Bumsoo Park, Sumaiya Islam, Raghavendra C. Vemulapalli, Maria E. Shreve   +3 more
doaj   +1 more source

Multiple therapeutic targets in rare cholestatic liver diseases: Time to redefine treatment strategies

Annals of Hepatology, 2020
Primary biliary cholangitis and primary sclerosing cholangitis are rare diseases affecting the bile ducts and the liver. The limited knowledge of their pathogenesis leads to limited therapeutic options.
Alessio Gerussi, Daphne D’Amato, Laura Cristoferi, Sarah Elizabeth O’Donnell, Marco Carbone, Pietro Invernizzi   +5 more
doaj   +1 more source

Primary Sclerosing Cholangitis Complicated with Aphthoid Colitis Difficult to Diagnose from IgG4-Related Sclerosing Cholangitis

Case Reports in Gastroenterology, 2022
A 19-year-old man visited our hospital because of diarrhea and blood and liver dysfunction. Magnetic and endoscopic retrograde cholangiography revealed diffuse narrowing of the common biliary tract and intrahepatic biliary tract.
Jin Imai, Hitoshi Ichikawa, Motoki Kaneko, Hiroyuki Ito, Shinji Takashimizu, Takayuki Shirai, Takuma Tajiri, Norihito Watanabe, Hidekazu Suzuki   +8 more
doaj   +1 more source

Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis

Hepatology, EarlyView., 2022
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr, Benedikt Kaufmann, Maria Eugenia Inzaugarat, Theresa Maria Holtmann, Lukas Geisler, Jana Hundertmark, Marlene Sophia Kohlhepp, Laela M. Boosheri, Daisy R. Chilin‐Fuentes, Amanda Birmingham, Kathleen M. Fisch, Joel D. Schilling, Sven H. Loosen, Christian Trautwein, Christoph Roderburg, Münevver Demir, Frank Tacke, Hal M. Hoffman, Ariel E. Feldstein, Alexander Wree   +19 more
wiley   +1 more source

Guidelines on the Diagnosis and Management of Primary Biliary Cholangitis (2021)

Journal of Clinical and Translational Hepatology, 2023
In 2015, the Chinese Society of Hepatology and the Chinese Society of Gastroenterology published a consensus on primary biliary cholangitis (PBC). In the past years, numerous clinical studies have been published in the field of PBC. To guide the clinical
H. You, W. Duan, Shuxiang Li, Tingting Lv, Shan-Shan Chen, Lungen Lu, Xiong Ma, Ying Han, Y. Nan, Xiaoyuan Xu, Z. Duan, Lai Wei, J. Jia, Z. Hui   +13 more
semanticscholar   +1 more source

Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy

Hepatology, EarlyView., 2022
Serum bile acid levels predict outcomes in patients with biliary atresia who achieve normalized bilirubin levels after Kasai portoenterostomy. Abstract Background and Aims In biliary atresia, serum bilirubin is commonly used to predict outcomes after Kasai portoenterostomy (KP).
Sanjiv Harpavat, Kieran Hawthorne, Kenneth D. R. Setchell, Monica Narvaez Rivas, Lisa Henn, Charlotte A. Beil, Saul J. Karpen, Vicky L. Ng, Estella M. Alonso, Jorge A. Bezerra, Stephen L. Guthery, Simon Horslen, Kathy M. Loomes, Patrick McKiernan, John C. Magee, Robert M. Merion, Jean P. Molleston, Philip Rosenthal, Richard J. Thompson, Kasper S. Wang, Ronald J. Sokol, Benjamin L. Shneider, for Childhood Liver Disease Research Network (ChiLDReN)   +22 more
wiley   +1 more source

Effect of stent placement on stone recurrence and post-procedural cholangitis after endoscopic removal of common bile duct stones [PDF]

The Korean Journal of Internal Medicine, 2021
Background/Aims After endoscopic treatment of common bile duct (CBD) stones, recurrence of choledocholithiasis due to small stone fragments and post-endoscopic retrograde cholangiopancreatography (post-ERCP) cholangitis can occur.
Jung-Hye Choi, Tae-Yoon Lee, Young-Koog Cheon   +2 more
doaj   +1 more source

Management of Primary Biliary Cholangitis: Current Treatment and Future Perspectives

The Turkish Journal of Gastroenterology, 2023
Primary biliary cholangitis is an autoimmune cholestatic liver disease characterized by progressive destruction of bile ducts, which can ultimately progress to chronic liver disease and cirrhosis.
Romelia Barba Bernal, Bryan Ferrigno, Esli Medina Morales, C. Castro, Daniela Goyes, H. Trivedi, V. Patwardhan, A. Bonder   +7 more
semanticscholar   +1 more source

P-105 PREVALENCE OF ANTIMITOCHONDRIAL ANTIBODIES IN PATIENTS WITH PRIMARY BILE CHOLANGITIS AND ITS OUTCOME IN LIVER TRANSPLANTATION

Annals of Hepatology, 2021
Introduction: The presence of antimitochondrial antibodies has been described as a diagnostic criterion for primary biliary cholangitis. However, no studies have been established in the South American population to describe the prevalence of these ...
Andres Gomez Aldana, Monica Tapias, Jose De la Hoz, Juanita Leon, Jannet Lopez, Alvaro Lozada   +5 more
doaj   +1 more source

Open‐label, clinical trial extension: Two‐year safety and efficacy results of seladelpar in patients with primary biliary cholangitis

Alimentary Pharmacology and Therapeutics, 2023
Seladelpar is a potent and selective peroxisome proliferator‐activated receptor‐δ agonist that targets multiple cell types involved in primary biliary cholangitis (PBC), leading to anti‐cholestatic, anti‐inflammatory and anti‐pruritic effects.
M. Mayo, J. Vierling, C. Bowlus, Cynthia Levy, G. Hirschfield, Guy W. Neff, Michael R. Galambos, S. Gordon, Brian B. Borg, Stephen A. Harrison, P. Thuluvath, A. Goel, M. Shiffman, M. Swain, David Jones, P. Trivedi, A. Kremer, Richard J. Aspinall, David A. Sheridan, Yvonne Dörffel, Ke Yang, Yun-Jung Choi, C. McWherter   +22 more
semanticscholar   +1 more source