Results 221 to 230 of about 42,278 (249)

Homozygous Loss‐of‐Function Variant in SLC20A1 Coding for Ubiquitous Phosphate Transporter PiT1 Is Associated With Multiple Developmental Abnormalities

Clinical Genetics, Volume 110, Issue 1, Page 64-72, July 2026.
Biallelic SLC20A1 loss‐of‐function variant causes a previously unrecognized multisystem developmental disorder. We report the first homozygous case presenting with tetralogy of Fallot, renal agenesis, polydactyly, and growth impairment. Transcriptome analysis of patient‐derived fibroblasts suggests significant dysregulation of pathways critical for ...
Eugénie Koumakis, Céline Huber, Wendy Chung, Christine Leroy, Pauline Parisot, Regis Gaudin, Mohamad Zaidan, Valérie Cormier‐Daire, Gérard Friedlander, Yoel Hirsch   +9 more
wiley   +1 more source

Aurora-A Promotes Cell-Cycle Progression From Quiescence Through Primary Cilia Disassembly. [PDF]

Cancer Sci
Kohso A, Inaba H, Kanemaki MT, Gabazza EC, Toyoda H, Hirayama M, Goto H.   +6 more
europepmc   +1 more source

Happiness and Smell: Overlooked Factors in Endoscopic Sinus Surgery?

Clinical Otolaryngology, Volume 51, Issue 4, Page 585-590, July 2026.
ABSTRACT Objective This study investigates the impact of functional endoscopic sinus surgery (FESS) on happiness levels in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) and examines the factors influencing postoperative happiness. Methods This study included 55 patients (34 males, 21 females; mean age, 41.2 ± 14.7 years) who underwent
Tuğba Tulacı, Omer Hizli, Hasan Çanakçı, Mustafa Utku Akbaş, Kamil Gökçe Tulacı   +4 more
wiley   +1 more source

New Insights into the Molecular Actions of Grosheimin, Costunolide, and α- and β-Cyclocostunolide on Primary Cilia Structure and Hedgehog Signaling. [PDF]

Int J Mol Sci
Murillo-Pineda M, Martínez-Miralles J, Medina-Calzada Z, Varela RM, Macías FA, Chinchilla N, Juárez-Soto Á, Santpere G, Reales E.   +8 more
europepmc   +1 more source

Mucous Membrane Pemphigoid After Anti‐PD‐1 Therapy: Risk‐Stratified Management and Treatment Outcomes

International Journal of Dermatology, Volume 65, Issue 7, Page 1376-1382, July 2026.
ABSTRACT Mucous membrane pemphigoid (MMP) following anti‐programmed cell death‐1 (PD‐1) therapy is rare but increasingly reported. Management of high‐ and low‐risk MMP in this setting and the potential oncologic trade‐offs remain poorly defined. We performed a narrative synthesis of all published cases of anti‐PD‐1‐associated MMP, following MEDLINE ...
Serena Dienes, Negar Esfandiari, Steven Daveluy   +2 more
wiley   +1 more source

PIEZO1-Primary Cilia Axis Mediates Compressive Stress-Induced Growth Plate Degeneration and Ossification in Adolescent Idiopathic Scoliosis. [PDF]

JOR Spine
Chen F, Chen S, Peng F, Du Y, Li J, Fan Y, Cui Z, Gu G, Zhang H, Jing X, Dong J, Li T, Xi Y.   +12 more
europepmc   +1 more source

Short‐Term Daily Oral Administration of Cannabidiol Does Not Impact Rebound Tonometry Intraocular Pressure or Schirmer Tear Test Values in Healthy Adult Horses

Veterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Objective To assess the effect of orally administered cannabidiol (CBD) on TonoVet measured intraocular pressure (IOP) and Schirmer tear test I (STT) in horses. Animal Studied Horse. Procedure This was a masked, randomized, balanced cross‐over study of six healthy adult horses.
Kathryn Diehl, Colleen Sheridan, Rachel Reed   +2 more
wiley   +1 more source

Prostaglandin E2 and Progesterone Receptor Coordinately Regulate Primary Cilia for Proper Decidualization. [PDF]

FASEB J
Lee CJ, Tsai YC, Chen TY, Chao YY, Lin RC, Tsai HL, Wen JY, Tang TK, Tsai PY, Kuo PL, Wang CY.   +10 more
europepmc   +1 more source

The Early Ophthalmic Effects of Vatinoxan in Healthy Detomidine‐Sedated Horses

Veterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Objective To evaluate the short‐term ophthalmic effects of vatinoxan, a peripherally selective alpha2‐adrenoceptor antagonist, in detomidine‐sedated horses. Animals Studied Seven healthy horses without ophthalmic disease in a randomized, masked, two‐period crossover study design, with a ≥ 7‐day rest period.
Minna Pauliina Mustikka, Ninja Pauliina Karikoski, Marja Riitta Raekallio, Elle Sofia Teppo, Simon Anton Pot, Juhana Honkavaara   +5 more
wiley   +1 more source

The DNA-PKcs-primary cilia axis maintains ionizing radiation-induced senescence in tumor cells. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Liu X, Wei L, Zhang R, Chen J, Zhang T, Hua J, Wang J, He J, Xie X.   +8 more
europepmc   +1 more source