Results 141 to 150 of about 322,522 (245)

Multimorbidity and animal models

Animal Models and Experimental Medicine, EarlyView.
Multimorbidity, defined as the coexistence of ≥2 chronic conditions, is associated with aging, genetics, and environmental factors. Animal models in multimorbidity research span three tiers: simple organisms for initial screening → rodents for mechanistic analysis → large mammals for clinical prediction.
Xinpei Wang, Yakun Ren, Xingjiu Yang, Mengyuan Li, Junxiu Liu, Xiaoyan Du, Wen Wang, Ran Gao   +7 more
wiley   +1 more source

Gastrointestinal Tract Findings in Patients with Primary Immunodeficiency: A Single-Center 6-Year Experience. [PDF]

Turk J Gastroenterol
Erkoç M, Erhan Ç, Çevirme L, Basır H, Dik S, Cansunar RS, Özden G.   +6 more
europepmc   +1 more source

Clinico-immunological profile of primary immunodeficiency diseases at a tertiary care children’s hospital in south india.

, 2018
Rishab Bharadwaj, L. Ajeitha, R. Revathi, M. Deenadayalan   +3 more
openalex   +1 more source

Development of an in situ small intestinal injection technique for targeted macromolecule delivery and in vivo functional studies in mice

Animal Models and Experimental Medicine, EarlyView.
This study developed a minimally invasive, in situ small intestinal injection technique for mice, enabling targeted delivery of bioactive molecules while bypassing gastric degradation. Validation using functional assays and single‐cell RNA sequencing reveals high‐mobility group box 1–mediated epithelial responses, offering a translational tool for gut ...
Yawen Lai, Xintao Zhang, Tingting Luo, Wenhan Chen, Chenyu Ma, Haihua Luo, Jinghua Liu, Jia Xu   +7 more
wiley   +1 more source

Treatment of Primary Immunodeficiency [PDF]

, 1975
I M Anderson
openalex   +1 more source

Novel variants related to extreme elevation of serum IgE in Vietnamese patients with primary immunodeficiency: Case report. [PDF]

Medicine (Baltimore)
Huong LTM, Lien NTK, Van Anh NT, Dien TM, Mai NTP, Ngoc ND, Thu NM, Ngan NTT, Hien NT, Van Tung N, Hoang NH.   +10 more
europepmc   +1 more source

Novel gene therapy advances for treating primary immunodeficiency disorders - an update. [PDF]

Ann Med Surg (Lond), 2023
Amin R, Darwin R, Chakraborty S, Dey BK, Dhama K, Emran TB.   +5 more
europepmc   +1 more source

Primary care physicians' refusal to care for patients infected with the human immunodeficiency virus. [PDF]

, 1992
C. E. Lewis, Kathleen Montgomery
openalex  

Complications Associated with Underweight Primary Immunodeficiency Patients: Prevalence and Associations Within the USIDNET Registry

, 2018
Melanie A. Ruffner, Kathleen E. Sullivan, Kathleen E. Sullivan   +2 more
openalex   +2 more sources

Late Pregnancy Antiseizure Medication Exposure and Offspring Neurodevelopmental Risk: A Multi‐Child Cohort Study

Annals of Neurology, EarlyView.
Objective Antiseizure medication (ASM) use during pregnancy has increased over the past decade. However, evidence linking prenatal ASM exposure to neurodevelopmental disorders (NDDs) in offspring remains inconsistent. This study evaluated whether prenatal ASM exposure increases the risk of NDDs in children.
Odile Sheehy, Vanina Tchuente, Sherif Eltonsy, Steven Hawken, Padma Kaul, Mark Walker, Michael Pugliese, Roxana Dragan, Anamaria Savu, Lisiane Leal, Lucie Morin, Isabelle Malhamé, Raluca Pana, Anick Bérard   +13 more
wiley   +1 more source