Results 181 to 190 of about 220,119 (313)

Diagnostic tests for primary immunodeficiency disorders: Classic and genetic testing. [PDF]

Allergy Asthma Proc
Klangkalya N, Fleisher TA, Rosenzweig SD.   +2 more
europepmc   +1 more source

Retrospective evaluation of adults with primary immunodeficiency disease. [PDF]

Postepy Dermatol Alergol, 2022
Özdemir E.
europepmc   +1 more source

Antiretroviral Therapy during Primary Immunodeficiency Virus Infection Can Induce Persistent Suppression of Virus Load and Protection from Heterologous Challenge in Rhesus Macaques [PDF]

, 2000
Brigitte Rosenwirth, Peter ten Haaft, Willy Bogers, Ivonne G. Nieuwenhuis, Henk Niphuis, Eva-Maria Kuhn, Norbert Bischofberger, Jonathan L. Heeney, Klaus Überla   +8 more
openalex   +1 more source

Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies

Annals of Neurology, EarlyView.
Autosomal recessive cerebellar ataxias are disabling neurodegenerative genetic conditions affecting balance and coordination. Advancements in genomic testing have improved diagnosis, leading to a new focus on the development of targeted precision therapeutics addressing cellular, biochemical, and genetic disease mechanisms with a resulting emphasis on ...
Brent L. Fogel, Thomas Klopstock, David R. Lynch, Francesca Maltecca, Mayank Verma, Berge A. Minassian, Frances M. Platt, Débora Farina Gonçalves, Hélène Puccio, Andreas Roos, Matthis Synofzik   +10 more
wiley   +1 more source

Diagnosis of mixed infection and a primary immunodeficiency disease using next-generation sequencing: a case report. [PDF]

Front Cell Infect Microbiol, 2023
Zhang X, Wang Y, Pen D, Liu J, Zhou Q, Wang Y, Zhong H, Liu T, Chen W, Wu B, Zhou Y, Wang C, Li X, Yu F, Wang X, Lu G, Yan G.   +16 more
europepmc   +1 more source

Adaptation to persistent growth in the H9 cell line renders a primary isolate of human immunodeficiency virus type 1 sensitive to neutralization by vaccine sera

, 1995
Terri Wrin, Tze Ping Loh, Joanne Vennari, Hanneke Schuitemaker, Jack H. Nunberg   +4 more
openalex   +1 more source

Progress in Biomimetic Microdevices for Anticancer Drug Screening and their Potential for Enhancing In Vivo Efficacy

Advanced NanoBiomed Research, EarlyView.
Biomimetic microdevices are redefining anticancer drug screening by mimicking complex tumor microenvironments. This review highlights advances in microfluidic systems, cell microarrays, and in vivo‐like models, offering new insights into drug efficacy prediction and personalized medicine. The development of effective anticancer drugs remains a critical
Ching‐Te Kuo, Yen‐Tzu Liao, Hsinyu Lee   +2 more
wiley   +1 more source

Immunoglobulin therapies for primary immunodeficiency diseases (part 1): understanding the pharmacokinetics. [PDF]

Immunotherapy
Mahmood I, Li Z.
europepmc   +1 more source

Patient-reported outcomes in patients with primary immunodeficiency diseases in Japan: baseline results from a prospective observational study. [PDF]

Front Immunol, 2023
Kanegane H, Ishimura M, Kawai T, Okada S, Okamatsu N, Go M, Noto S.   +6 more
europepmc   +1 more source

The Chemistry and Biology of the Tetrodotoxin Natural Product Family

Angewandte Chemie International Edition, EarlyView.
Tetrodotoxin is best known as the poison of the pufferfish, which is a delicacy in Japanese cuisine. Its toxicity arises from the selective blockage of NaV channels, which is depicted for the NaV1.7 pore, highlighting the DEKA motif, which permeates sodium ions.
Benedikt Nißl, Marcel Mülbaier, Francesca Grisoni, Dirk Trauner, Marcel Bermúdez, Clemens Dialer, David B. Konrad   +6 more
wiley   +1 more source