Results 21 to 30 of about 220,119 (313)

Evaluation of Humoral and Cellular Immune Responses to the SARS-CoV-2 Vaccine in Patients With Common Variable Immunodeficiency Phenotype and Patient Receiving B-Cell Depletion Therapy

Frontiers in Immunology, 2022
IntroductionSARS-CoV-2 vaccines’ effectiveness is not yet clearly known in immunocompromised patients. This study aims to assess the humoral and cellular specific immune response to SARS-CoV-2 vaccines and the predictors of poor response in patients with
Arnau Antolí, Arnau Antolí, Arnau Antolí, Gemma Rocamora-Blanch, Gemma Rocamora-Blanch, Gemma Rocamora-Blanch, Mario Framil, Mario Framil, Mario Framil, Virgínia Mas-Bosch, Virgínia Mas-Bosch, Virgínia Mas-Bosch, Sergio Navarro, Sergio Navarro, Sergio Navarro, Carla Bermudez, Carla Bermudez, Sergio Martinez-Yelamos, Sergio Martinez-Yelamos, Sergio Martinez-Yelamos, Eva Dopico, Eva Dopico, Laura Calatayud, Laura Calatayud, Laura Calatayud, Nadia Garcia-Muñoz, Luis Humberto Hernández-Benítez, Antoni Riera-Mestre, Antoni Riera-Mestre, Antoni Riera-Mestre, Jordi Bas, Jordi Bas, Jordi Bas, Cristina Masuet-Aumatell, Cristina Masuet-Aumatell, Cristina Masuet-Aumatell, Raúl Rigo-Bonnin, Raúl Rigo-Bonnin, Francisco Morandeira, Francisco Morandeira, Francisco Morandeira, Xavier Solanich, Xavier Solanich, Xavier Solanich   +43 more
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Minor Clinical Impact of COVID-19 Pandemic on Patients With Primary Immunodeficiency in Israel

Frontiers in Immunology, 2021
In the last few months the world has witnessed a global pandemic due to severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection causing coronavirus disease 2019 (COVID-19).
Nufar Marcus, Nufar Marcus, Nufar Marcus, Shirly Frizinsky, Shirly Frizinsky, Shirly Frizinsky, Shirly Frizinsky, Shirly Frizinsky, David Hagin, David Hagin, David Hagin, Adi Ovadia, Adi Ovadia, Adi Ovadia, Suhair Hanna, Suhair Hanna, Michael Farkash, Michael Farkash, Michael Farkash, Ramit Maoz-Segal, Ramit Maoz-Segal, Ramit Maoz-Segal, Nancy Agmon-Levin, Nancy Agmon-Levin, Nancy Agmon-Levin, Arnon Broides, Arnon Broides, Amit Nahum, Amit Nahum, Elli Rosenberg, Elli Rosenberg, Amir Asher Kuperman, Amir Asher Kuperman, Yael Dinur-Schejter, Yael Dinur-Schejter, Yackov Berkun, Yackov Berkun, Ori Toker, Ori Toker, Ori Toker, Shmuel Goldberg, Shmuel Goldberg, Ronit Confino-Cohen, Ronit Confino-Cohen, Oded Scheuerman, Basel Badarneh, Basel Badarneh, Na‘ama Epstein-Rigbi, Amos Etzioni, Amos Etzioni, Ilan Dalal, Ilan Dalal, Ilan Dalal, Ilan Dalal, Raz Somech, Raz Somech   +55 more
doaj   +1 more source

A Computational Pipeline for the Diagnosis of CVID Patients

Frontiers in Immunology, 2019
Common variable immunodeficiency (CVID) is one of the most frequently diagnosed primary antibody deficiencies (PADs), a group of disorders characterized by a decrease in one or more immunoglobulin (sub)classes and/or impaired antibody responses caused by
Annelies Emmaneel, Annelies Emmaneel, Delfien J. Bogaert, Delfien J. Bogaert, Sofie Van Gassen, Sofie Van Gassen, Simon J. Tavernier, Simon J. Tavernier, Simon J. Tavernier, Melissa Dullaers, Filomeen Haerynck, Filomeen Haerynck, Yvan Saeys, Yvan Saeys   +13 more
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Primary Immunodeficiencies [PDF]

Mayo Clinic Proceedings, 1998
The primary immunodeficiencies are congenital disorders that affect the function of the immune system. The result is an inadequate immune response to microorganisms, self-antigens, and tumor cells, which leads to increased susceptibility to infections, autoimmunity, or malignant disease.
openaire   +2 more sources

Comparison of [3H]-Thymidine, Carboxyfluorescein Diacetate Succinimidyl Ester and Ki-67 in Lymphocyte Proliferation

Frontiers in Pediatrics, 2022
BackgroundPatients with T cell deficiency <10% of normal proliferation are indicated to receive immune reconstruction by hematopoietic stem cell transplantation (HSCT).
Hsin-Ju Lee, Chun-Chun Gau, Chun-Chun Gau, Chun-Chun Gau, Wan-Fang Lee, Wen-I Lee, Wen-I Lee, Jing-Long Huang, Jing-Long Huang, Jing-Long Huang, Shih-Hsiang Chen, Ho-Yu Yeh, Chi-Jou Liang, Shih-Hang Fu   +13 more
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Whole exome sequencing identifies compound heterozygous variants of gene in monozygotic twin patients with common variable immunodeficiency

SAGE Open Medicine, 2020
Objectives: A pair of female Malay monozygotic twins who presented with recurrent upper respiratory tract infections, hepatosplenomegaly, bronchiectasis and bicytopenia were recruited in this study.
Adiratna Mat Ripen, Hamidah Ghani, Chai Teng Chear, Mei Yee Chiow, Sharifah Nurul Husna Syed Yahya, Asiah Kassim, Saharuddin Bin Mohamad   +6 more
doaj   +1 more source

Entry into the lytic cycle exposes EBV-infected cells to NK cell killing via upregulation of the MICB ligand for NKG2D and activation of the CD56bright and NKG2A+KIR+CD56dim subsets

Frontiers in Immunology
The Epstein–Barr virus (EBV) is usually acquired during infancy as an asymptomatic infection and persists throughout life in a latent state under the control of the host immune system.
Maria Giovanna Desimio, Daniela Angela Covino, Caterina Cancrini, Caterina Cancrini, Margherita Doria   +4 more
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Clinical and demographic pattern of chronic granulomatous disease (CGD) from a multicenter perspective: Malaysia’s experience over 26 years

Allergy, Asthma & Clinical Immunology, 2021
Background A retrospective review of clinical manifestations and demographic pattern of patients diagnosed as chronic granulomatous disease (CGD) from 7 hospitals in Malaysia. An analysis of the available database would establish clinical characteristics,
Lokman Mohd Noh, Amir Hamzah Abdul Latiff, Intan Hakimah Ismail, Rahim Md Noah, Asrul Abdul Wahab, Intan Juliana Abd. Hamid, Adiratna Mat Ripen, Nasuruddin B. Abdullah, Kamarul Azhar Razali, Norzila Zainudin, Florence Bakon, Long Juan Kok, Adli Ali, Bilkis Banu SAbd Aziz, Hasniah Abdul Latif, Siti Mardhiana Mohamad, Zarina Thasneem Zainudeen, Ilie Fadzilah Hashim, Iean Hamzah Sendut, Thiyagar Nadarajaw, Faizah Mohamed Jamil, David C. E. Ng, Mohd Azri Zainal Abidin   +22 more
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Ataxia Telangiectasia Diagnosed on Newborn Screening–Case Cohort of 5 Years' Experience

Frontiers in Immunology, 2019
Ataxia telangiectasia (AT) is a genetic condition caused by mutations involving ATM (Ataxia Telangiectasia Mutated). This gene is responsible for the expression of a DNA double stranded break repair kinase, the ATM protein kinase.
Amarilla B. Mandola, Amarilla B. Mandola, Brenda Reid, Brenda Reid, Raga Sirror, Rae Brager, Peter Dent, Pranesh Chakroborty, Dennis E. Bulman, Chaim M. Roifman, Chaim M. Roifman   +10 more
doaj   +1 more source

BCG: a vaccine with multiple faces

Human Vaccines & Immunotherapeutics, 2020
BCG has been recommended because of its efficacy against disseminated and meningeal tuberculosis. The BCG vaccine has other mechanisms of action besides tuberculosis protection, with immunomodulatory properties that are now being discovered. Reports have
Marco Antonio Yamazaki-Nakashimada, Alberto Unzueta, Luisa Berenise Gámez-González, Napoleón González-Saldaña, Ricardo U. Sorensen   +4 more
doaj   +1 more source