Results 21 to 30 of about 483,399 (234)
Consanguinity and Primary Immunodeficiencies [PDF]
Human Heredity, 2014 Primary immunodeficiencies (PIDs) are a heterogeneous group of genetic disorders caused by defects in the immune system that predispose patients to infections, autoimmune diseases, lymphoproliferation and malignancies. Most PIDs are inherited in an autosomal recessive pattern; therefore, they are more common in areas with high rates of consanguineous ...
Waleed Al-Herz +3 more
openaire +2 more sources
Evolution of replication efficiency following infection with a molecularly cloned feline immunodeficiency virus of low virulence [PDF]
, 2002 The development of an effective vaccine against human immunodeficiency virus is considered to be the most practicable means of controlling the advancing global AIDS epidemic.
Cannon, C. +7 more
core +2 more sources
Primary immunodeficiency and the microbiome
Current Opinion in Pediatrics, 2021 Purpose of review The current understanding of the relationship of the microbiota to clinical manifestation in patients with primary immunodeficiency, specifically the inflammatory processes caused by or that result in microbial dysbiosis, and their potential therapeutic options in primary immunodeficiency diseases (PID), is ...
Maryam Ali Al-Nesf +2 more
openaire +3 more sources
PPARγ and LXR Signaling Inhibit Dendritic Cell-Mediated HIV-1 Capture and trans-Infection [PDF]
, 2010 Dendritic cells (DCs) contribute to human immunodeficiency virus type 1 (HIV-1) transmission and dissemination by capturing and transporting infectious virus from the mucosa to draining lymph nodes, and transferring these virus particles to CD4+ T cells ...
Blay Puryear, Wendy +3 more
core +11 more sources
Subcutaneous IgG Replacement Therapy by Push in 32 Patients with Primary Immunodeficiency Diseases in Argentine [PDF]
, 2014 Introduction: Regular replacement with immunoglobulin infusions is the mainstay of treatment in the majority of primary immunodeficiencies. Several studies showed that Subcutaneous Immunoglobulin (SCIG) has similar efficacy to Intravenous Immunoglobulin (
Bezrodnik, Liliana +6 more
core +1 more source
A rare primary immunodeficiency [PDF]
BMJ Case Reports, 2014 A 9-year-old girl presented with failure to thrive, chronic mucopurulent nasal discharge, recurrent skin pustules and recurrent episodes of purulent ear discharge since 2 years of age. She had coarse facial features with extensive eczema, multiple pyoderma scars, florid dental caries, retained primary dentition, hypermobile joints and a woody ...
Shobhana Sivathanu +3 more
openaire +3 more sources
Case Report: Association between cyclic neutropenia and SRP54 deficiency
Frontiers in Immunology, 2022 Autosomal dominant mutations in the signal recognition particle (SRP) 54 gene were recently described in patients with severe congenital neutropenia (SCN).
Melinda Erdős +4 more
doaj +1 more source
Selective IgM Deficiency—An Underestimated Primary Immunodeficiency
Frontiers in Immunology, 2017 Although selective IgM deficiency (SIGMD) was described almost five decades ago, it was largely ignored as a primary immunodeficiency. SIGMD is defined as serum IgM levels below two SD of mean with normal serum IgG and IgA.
Sudhir Gupta, Ankmalika Gupta
doaj +1 more source
Frontiers in Immunology, 2022 IntroductionSARS-CoV-2 vaccines’ effectiveness is not yet clearly known in immunocompromised patients. This study aims to assess the humoral and cellular specific immune response to SARS-CoV-2 vaccines and the predictors of poor response in patients with
Arnau Antolí +43 more
doaj +1 more source
Minor Clinical Impact of COVID-19 Pandemic on Patients With Primary Immunodeficiency in Israel
Frontiers in Immunology, 2021 In the last few months the world has witnessed a global pandemic due to severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection causing coronavirus disease 2019 (COVID-19).
Nufar Marcus +55 more
doaj +1 more source