Results 31 to 40 of about 5,337,098 (424)

Impact of SARS-CoV-2 Pandemic on Patients with Primary Immunodeficiency

open access: yesJournal of Clinical Immunology, 2020
Although it is estimated that COVID-19 life-threatening conditions may be diagnosed in less than 1:1000 infected individuals below the age of 50, but the real impact of this pandemic on pediatric patients with different types of primary immunodeficiency (
S. Delavari   +28 more
semanticscholar   +1 more source

Isolated Nocardiosis, an Unrecognized Primary Immunodeficiency?

open access: yesFrontiers in Immunology, 2020
Nocardiosis is an infectious disease caused by the gram-positive bacterium Nocardia spp. Although it is commonly accepted that exposure to Nocardia is almost universal, only a small fraction of exposed individuals develop the disease, while the vast ...
Ruben Martinez-Barricarte
semanticscholar   +1 more source

Systematic Review of Primary Immunodeficiency Diseases in Malaysia: 1979–2020

open access: yesFrontiers in Immunology, 2020
Introduction: Primary immunodeficiency diseases (PIDs) are under-reported in Malaysia. The actual disease frequency of PID in this country is unknown due to the absence of a national patient registry for PID.Objective: This systematic review aimed to ...
Intan Juliana Abd Hamid   +5 more
doaj   +1 more source

Comparison of SARS-CoV-2 seroconversion in children with chronic diseases with healthy children and adults during the first waves of the COVID-19 pandemic

open access: yesFrontiers in Pediatrics, 2023
BackgroundInfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is clinically diverse, and children have a low risk of developing severe coronavirus disease 2019 (COVID-19). However, children with chronic diseases have a potentially
Levi Hoste   +15 more
doaj   +1 more source

Global systematic review of primary immunodeficiency registries

open access: yesExpert Review of Clinical Immunology, 2020
Introduction During the last 4 decades, registration of patients with primary immunodeficiencies (PID) has played an essential role in different aspects of these diseases worldwide including epidemiological indexes, policymaking, quality controls of care/
Hassan Abolhassani   +29 more
semanticscholar   +1 more source

Recent advances in primary immunodeficiency: from molecular diagnosis to treatment

open access: yesF1000Research, 2020
The technological advances in diagnostics and therapy of primary immunodeficiency are progressing at a fast pace. This review examines recent developments in the field of inborn errors of immunity, from their definition to their treatment.
G. Bucciol, I. Meyts
semanticscholar   +1 more source

Update in Primary Immunodeficiencies.

open access: yesActa bio-medica : Atenei Parmensis, 2020
Primary immunodeficiencies (PIDs) are inherited disorders classically characterized by increased susceptibility to infections. Nevertheless, in the last two decades, genomic analysis (such as NGS) coupled with biochemical and cellular studies led to a more accurate definition for a growing number of novel genetic disorders associated with PIDs.
Leonardi L.   +12 more
openaire   +3 more sources

Primary vs. Secondary Antibody Deficiency: Clinical Features and Infection Outcomes of Immunoglobulin Replacement [PDF]

open access: yes, 2014
Secondary antibody deficiency can occur as a result of haematological malignancies or certain medications, but not much is known about the clinical and immunological features of this group of patients as a whole. Here we describe a cohort of 167 patients
AA Bousfiha   +55 more
core   +15 more sources

Homozygous duplication identified by whole genome sequencing causes LRBA deficiency

open access: yesnpj Genomic Medicine, 2021
In more than one-third of primary immunodeficiency (PID) patients, extensive genetic analysis including whole-exome sequencing (WES) fails to identify the genetic defect.
Daniele Merico   +14 more
doaj   +1 more source

Evaluation of Humoral and Cellular Responses in SARS-CoV-2 mRNA Vaccinated Immunocompromised Patients

open access: yesFrontiers in Immunology, 2022
BackgroundImmunocompromised patients are at increased risk of severe COVID-19 and impaired vaccine response. In this observational prospective study, we evaluated immunogenicity of the BNT162b2 mRNA vaccine in cohorts of primary or secondary ...
Matthijs Oyaert   +19 more
doaj   +1 more source

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