Results 51 to 60 of about 357,486 (216)

A patient with complete IFN-γR1 deficiency and tuberculosis resembling BCG diseaseIFN-γR1 deficiency and Mycobacterium tuberculosis [PDF]

Journal of Human Immunity
We present a case of a patient with a deleterious variant in IFNGR1 who contracted Mycobacterium tuberculosis. However, the patient presented with clinical manifestations suggestive of BCG infection.
Sara Espinosa-Padilla, Héctor Gómez-Tello, Carlos Sanchez-Flores, Uriel Pérez-Blanco, Tiareth Cova-Guzmán, Stéphanie Boisson-Dupuis, Jacinta Bustamante, Lizbeth Blancas-Galicia   +7 more
doaj   +1 more source

Relationship Between Non-Hodgkin's Lymphoma and Blood Levels of Epstein-Barr Virus in Children in North-Western Tanzania: A Case Control Study. [PDF]

, 2013
Non-Hodgkin's Lymphomas (NHL) are common in African children, with endemic Burkitt's lymphoma (BL) being the most common subtype. While the role of Epstein-Barr Virus (EBV) in endemic BL is known, no data are available about clinical presentations of NHL
AH Filipovich, Anita De Rossi, AO Cavdar, Benson Kidenya, CE Klumb, D Kim, Damas Mwizamuholya, E Righetti, EK Mbidde, Erasmus Kamugisha, F Davi, G Nunnari, I Abbate, I Araujo, J Diebold, J Shapira, JES The, JL Young Jr, JT Sandlund, Kelsey, Maria Raffaella Petrara, MD Ogwang, MD Parkin, Ministry of Health and social welfare, MJ Boyle, MR Petrara, N Anwar, N Burighel, N Mutalima, National AIDS Control Programme, Nestory Masalu, P Aka, PA Chabay, Peter Rambau, R Hassan, R Newton, R Newton, RE Goldsby, Rogatus Kabyemera, S Lazzi, SB Murphy, SB Murphy, SC Peh, SJ Stevens, SM Mbulaiteye   +44 more
core   +3 more sources

Evaluation of MicroRNA-125b-5p and Transcription Factors BLIMP1 and IRF4 Expression in Unsolved Common Variable Immunodeficiency Patients

Iranian Journal of Allergy, Asthma and Immunology, 2021
Common variable immunodeficiency (CVID) is the most prevalent form of symptomatic primary humoral immunodeficiencies characterized by failure in the final differentiation of B lymphocytes. The majority of CVID cases have no identified genetic defect, and
Zahra Hamidi Esfahani, Reza Yazdani, Sepideh Shahkarami, Fateme Babaha, Hassan Abolhassani, Maryam Sadr, Ali Akbar Pourfathollah, Asghar Aghamohammadi   +7 more
doaj   +1 more source

Primary Immunodeficiency Diseases in Norway [PDF]

Journal of Clinical Immunology, 2000
This study represents the first national epidemiological survey of primary immunodeficiency diseases in Norway. Uniform questionnaires were sent out in April 1998 to all hospital departments considered relevant. As of February 1999, a total of 372 patients have been registered, of whom 69 patients are deceased. With a population of 4.45 million people,
A, Stray-Pedersen, T G, Abrahamsen, S S, Frøland   +2 more
openaire   +2 more sources

Immediate Antiretroviral Therapy Decreases Mortality Among Patients With High CD4 Counts in China: A Nationwide, Retrospective Cohort Study. [PDF]

, 2017
BackgroundClinical trials have demonstrated that immediate initiation of antiretroviral therapy (ART) reduces AIDS-related morbidity and mortality. We tested the hypothesis that initiating ART ≤30 days after human immunodeficiency virus (HIV) diagnosis ...
Brookmeyer, Ron, Detels, Roger, Dou, Zhihui, Li, Aihua, Ma, Ye, McGoogan, Jennifer M, Montaner, Julio SG, Qin, Qianqian, Shi, Cynthia X, Wu, Zunyou, Zhao, Yan   +10 more
core   +1 more source

Subjective assessment of sleep quality in adult patients with hereditary angioedema

Frontiers in Neurology
BackgroundHereditary angioedema (HAE) is a rare disorder characterized by recurrent swelling episodes, including painful abdominal attacks and life-threatening angioedema of the larynx that significantly affects patients’ quality of life, including sleep.
Esra Karabiber, Ezgi Yalçın Güngören, Ezgi Yalçın Güngören, Ezgi Yalçın Güngören, Ahmet Özen, Ahmet Özen, Ahmet Özen, Safa Barış, Safa Barış, Safa Barış, Elif Karakoc-Aydiner, Elif Karakoc-Aydiner, Elif Karakoc-Aydiner   +12 more
doaj   +1 more source

Defective germinal center selection results in persistence of self-reactive B cells from the primary to the secondary repertoire in Primary Antiphospholipid Syndrome

Nature Communications
Primary antiphospholipid syndrome (PAPS) is a life-threatening clotting disorder mediated by pathogenic autoantibodies. Here we dissect the origin of self-reactive B cells in human PAPS using peripheral blood and bone marrow of patients with triple ...
Yannick Dieudonné, Raquel Lorenzetti, Julien Rottura, Iga Janowska, Quentin Frenger, Léa Jacquel, Olivier Vollmer, Francesco Carbone, Zhu Chengsong, Marine Luka, Sabine Depauw, Nadège Wadier, Stéphane Giorgiutti, Benoît Nespola, Agathe Herb, Reinhard Edmund Voll, Aurélien Guffroy, Vincent Poindron, Mickaël Ménager, Thierry Martin, Pauline Soulas-Sprauel, Marta Rizzi, Anne-Sophie Korganow, Vincent Gies   +23 more
doaj   +1 more source

Flow cytometry-based diagnosis of primary immunodeficiency diseases

Allergology International, 2018
Primary immunodeficiencies (PIDs) are a heterogeneous group of inherited diseases of the immune system. The definite diagnosis of PID is ascertained by genetic analysis; however, this takes time and is costly.
Hirokazu Kanegane, Akihiro Hoshino, Tsubasa Okano, Takahiro Yasumi, Taizo Wada, Hidetoshi Takada, Satoshi Okada, Motoi Yamashita, Tzu-wen Yeh, Ryuta Nishikomori, Masatoshi Takagi, Kohsuke Imai, Hans D. Ochs, Tomohiro Morio   +13 more
doaj   +1 more source

Murine cytomegalovirus genomic material in marrow cells; relation to altered leukocyte counts during sublethal infection of mice [PDF]

, 1987
To investigate infection of hematopoietic cells by murine cytomegalovirus (MCMV), we used in situ hybridization to detect MCMV genomic material in marrow cells during sublethal infection of three-week-old mice.
Bale, J. F., Giller, R., Koszinowski, Ulrich H., O'Neil, M. E., Perlman, S.   +4 more
core   +1 more source

Stem Cell Transplantation for Primary Immunodeficiency Disease: Experience of a Singapore Hospital

World Allergy Organization Journal, 2012
We retrospectively analyzed the outcomes of hematopoietic stem cell transplantation in 7 patients with primary immunodeficiency diseases treated at the National University Hospital, Singapore, over the period from December 1996 to January 2010.
Alison Joanne Lee, MBBS, MRCPCH, MMed, Jethro Wu, MBBS, Mariflor Sarmiento Villegas, MD, Lynette Pei-Chi Shek, MBBS, MRCP, Bee-Wah Lee, MBBS, MMed, MD, FRCP, FRCPCh, FAAAAI, Poh-Lin Tan, MBBS, MMed   +5 more
doaj   +1 more source