Results 11 to 20 of about 728,235 (280)
Plant secondary metabolites as defenses, regulators and primary metabolites- The blurred functional trichotomy [PDF]
Plant Physiology, 2020 The plant kingdom produces hundreds of thousands of small molecular weight organic compounds. Based on their assumed functions, the research community has classified them into three overarching groups: primary metabolites which are directly required for plant growth, secondary (or specialized) metabolites which mediate plant-environment interactions ...
Matthias Erb, Daniel J. Kliebenstein
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Agriculture, 2022 The study was conducted during the harvest season in the year 2020 to identify and quantify primary and secondary metabolites in olive fruit of the ‘Leccino’ cultivar during ripening.
Tea Ivancic +4 more
doaj +1 more source
Metabolic regulation and overproduction of primary metabolites [PDF]
Microbial Biotechnology, 2008 Summary Overproduction of microbial metabolites is related to developmental phases of microorganisms. Inducers, effectors, inhibitors and various signal molecules play a role in different types of overproduction. Biosynthesis of enzymes catalysing metabolic reactions in microbial cells is controlled by well‐known positive and negative
Sanchez, Sergio, Demain, Arnold L.
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Screening Trimethoprim Primary Metabolites for Covalent Binding to Albumin. [PDF]
Med Chem Res, 2020 Modification of endogenous proteins by drugs and drug metabolites are thought to be a cause of idiosyncratic adverse drug reactions (IADRs). Trimethoprim (TMP) is a commonly prescribed antibiotic that has been implicated in IADRs; however, there is no known mechanism by which this drug or its metabolites modify proteins.
Nolte WM, Tessman RT, Goldman JL.
europepmc +4 more sources
Vagus Nerve Stimulation in Refractory Epilepsy: Effects on Pro- and Anti-Inflammatory Cytokines in Peripheral Blood [PDF]
, 2010 Objective: The vagus nerve has important immunological functions that may be relevant for its anticonvulsive action. We postulate that this anticonvulsive action is activated by a shift in the immune system resulting in a reduction of neurotoxic and an ...
Berfelo, M. W. +6 more
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Разработка и регистрация лекарственных средств, 2021 Introduction. Understanding the mechanisms of accumulation of individual groups of biologically active substances in promising types of plant raw materials and the possibility of predicting them is important for solving fundamental and applied problems ...
J. Strugar, A. A. Orlova, M. N. Povydysh
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Structure-based selection of human metabolite binding P4 pocket of DRB1*15:01 and DRB1*15:03, with implications for multiple sclerosis. [PDF]
, 2018 Binding of small molecules in the human leukocyte antigen (HLA) peptide-binding groove may result in conformational changes of bound peptide and an altered immune response, but previous studies have not considered a potential role for endogenous ...
Damotte, Vincent +2 more
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The role of the phosphopantetheinyltransferase enzyme, PswP, in the biosynthesis of antimicrobial secondary metabolites by Serratia marcescens Db10 [PDF]
, 2014 Phosphopantetheinyltransferase (PPTase) enzymes fulfil essential roles in primary and secondary metabolism in prokaryotes, archaea and eukaryotes. PPTase enzymes catalyse the essential modification of the carrier protein domain of fatty acid synthases ...
Amy J. Gerc +9 more
core +4 more sources
Plants, 2021 Plant production in a plant factory is an innovative and smart idea to grow food anytime, anywhere, regardless of the outer environment. However, potato pre-basic seed tuber (PBST) production in a plant factory is a comparatively new initiative ...
Md Hafizur Rahman +5 more
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Sensitivity of activated human lymphocytes to cyclosporine and its metabolites [PDF]
, 1988 Alloreactive T cells generated as clones from mixed lymphocyte cultures, or propagated from heart or liver transplant biopsies, were tested for secondary proliferation measured in the primed lymphocyte test in the presence of Cyclosporine A and ...
Burckart, G +8 more
core +1 more source