Results 71 to 80 of about 728,235 (280)

Metabolomics profiling of strawberry (Fragaria x ananassa) F1 population to characterize flavour and nutritional traits [PDF]

, 2018
The cultivated strawberry (Fragaria x ananassa) is a highly consumed fruit known for its delicate flavour and nutritional characteristics. However, as fruit quality attributes have been lost after years of traditional breeding, new technological tools ...
Amaya, Iraida, Fernie, Alisdair R, Medina, Juan Jesus, Osorio-Algar, Sonia, Potss, Potss, Delphine, Vallarino, Jose G   +6 more
core  

Halophiles and Their Biomolecules: Recent Advances and Future Applications in Biomedicine [PDF]

, 2020
The organisms thriving under extreme conditions better than any other organism living on Earth, fascinate by their hostile growing parameters, physiological features, and their production of valuable bioactive metabolites.
Amoozegar, Mohammad Ali, Corral Villa, Paulina, Ventosa Ucero, Antonio   +2 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Traditional Tomato Varieties Improve Fruit Quality Without Affecting Fruit Yield Under Moderate Salt Stress

Frontiers in Plant Science, 2020
Identification of tomato varieties able to exhibit higher accumulation of primary and secondary metabolites in their fruits is currently a main objective in tomato breeding.
Silvia L. R. Meza, Silvia L. R. Meza, Isabel Egea, Isabel L. Massaretto, Belén Morales, Eduardo Purgatto, José M. Egea-Fernández, María C. Bolarin, Francisco B. Flores   +8 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Microalgae-derived bioactive compounds: metabolic potential, extraction strategies, and sustainable applications in food, pharmaceuticals, and animal feed

Applied Phycology
This paper critically reviews how the metabolic potential of microalgae can be harnessed for the food, pharmaceutical, and animal feed industries by integrating cultivation system design with green extraction technologies, emphasizing their combined ...
Ng Jia Xuan, Hizriana Nuril Fitri Herryady, Siti Nur Hazwani Oslan, Sitti Raehanah Muhamad Shaleh, Mohd–Shamzi Mohamed, Asep Awaludin Prihanto, Andi Weri Sompa, Nurul Huda   +7 more
doaj   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

The Role of Taraxacum mongolicum in a Puccinellia tenuiflora Community under Saline–Alkali Stress

Molecules, 2022
Coexisting salt and alkaline stresses seriously threaten plant survival. Most studies have focused on halophytes; however, knowledge on how plants defend against saline–alkali stress is limited. This study investigated the role of Taraxacum mongolicum in
Xueyan Lu, Yan Jin, Xiaorui Guo, Mingyuan Xu, Zhonghua Tang, Qi Chen   +5 more
doaj   +1 more source

Metabolomic analysis of human oral cancer cells with adenylate kinase 2 or phosphorylate glycerol kinase 1 inhibition. [PDF]

, 2017
The purpose of this study was to use liquid chromatography-mass spectrometry (LC-MS) with XCMS for a quantitative metabolomic analysis of UM1 and UM2 oral cancer cells after knockdown of metabolic enzyme adenylate kinase 2 (AK2) or phosphorylate glycerol
Cheng, Siliangyu, Cui, Li, Hu, Shen, Ji, Eoon Hye, Messadi, Diana, Yan, Xinmin, Yuan, Xiaoqing   +6 more
core   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source