Results 91 to 100 of about 10,903,755 (367)
A Middle-Aged Enzyme Still in Its Prime: Recent Advances in the Field of Cutinases
Catalysts, 2018 Cutinases are α/β hydrolases, and their role in nature is the degradation of cutin. Such enzymes are usually produced by phytopathogenic microorganisms in order to penetrate their hosts. The first focused studies on cutinases started around 50 years ago.
E. Nikolaivits +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Dihedral Congruence Primes and Class Fields of Real Quadratic Fields
Journal of Number Theory, 2002 The author characterizes the primes \(p\) such that the congruence \(f\equiv f\otimes\mod{\wp}\) holds for primitive cusp forms \(f\) of weight \(k\geq 2\) and quadratic nebentypus \(\chi=\chi_1\chi_2\), and a prime \(\wp\) of \(\overline{\mathbb Q}\) above \(p\), where \(\chi_1\) is even quadratic. Such primes are called dihedral. They are essentially
Brown, Alexander F., Ghate, Eknath P.
openaire +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Journal of automated reasoning, 2013 In this paper, we introduce our formalization of the definitions and theorems related to an elliptic curve over a finite prime field. The elliptic curve is important in an elliptic curve cryptosystem whose security is based on the computational ...
Yuichi Futa +2 more
semanticscholar +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Special prime numbers and discrete logs in finite prime fields [PDF]
Mathematics of Computation, 2000 Summary: A set \(A\) of primes \(p\) involving numbers such as \(ab^t+c\), where \(| a|,| b|,| c|=O(1)\) and \(t\to\infty\), is defined. An algorithm for computing discrete logs in the finite field of order \(p\) with \(p\in A\) is suggested. Its heuristic expected running time is \(L_p[\frac13;(\frac{32}{9})^{1/3}]\) for \((\frac{32}{9})^{1/3}=1.526 ...
openaire +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source