Results 71 to 80 of about 143,448 (228)
On the emergence of the Quanta Prime sequence
Arab Journal of Basic and Applied SciencesThis paper presents the Quanta Prime Sequence (QPS) and its foundational theorem, showcasing a unique class of polynomials with substantial implications.
Moustafa Ibrahim
doaj +1 more source
Una aproximación a la Conjetura de Goldbach
Ecomatemático, 2019 One of the mathematical problems that seems to be very true, but lacks a demonstration, is Goldbach's conjecture posed since 1742.The present article makes a critical analysis, where several proposals for its solution were compiled, with a ...
Ingrid Yurley Parada-Buitrago +2 more
doaj +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
A note on Sturm-Liouville problems whose spectrum is the set of prime numbers
Electronic Journal of Differential Equations, 2011 We show that there is no classical regular Sturm-Liouville problem on a finite interval whose spectrum consists of infinitely many distinct primes numbers. In particular, this answers in the negative a question raised by Zettl in his book [9].
Angelo B. Mingarelli
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On an inequality about Euler's totient function [PDF]
Notes on Number Theory and Discrete MathematicsIn this paper, we show that when Nₖ is a primorial and φ(Nₖ) is Euler's totient function, the inequality φ(Nₖ)44.
Cheng-Ting Wang
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Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Subsets of prime numbers received by means of generalized arithmetic progression
Дифференциальная геометрия многообразий фигур, 2018 A short historical information about formulas and polynomials generating subsets of prime numbers is given. Examples of subsets of prime numbers by using generalized arithmetic progression are obtained.
V. Malakhovsky
doaj