Results 81 to 90 of about 137,442 (242)

Follistatin288 Regulates Germ Cell Cyst Breakdown and Primordial Follicle Assembly in the Mouse Ovary. [PDF]

PLoS ONE, 2015
In mammals, the primordial follicle pool represents the entire reproductive potential of a female. The transforming growth factor-β (TGF-β) family member activin (ACT) contributes to folliculogenesis, although the exact mechanism is not known.
Zhengpin Wang, Wanbao Niu, Yijing Wang, Zhen Teng, Jia Wen, Guoliang Xia, Chao Wang   +6 more
doaj   +1 more source

Characterisation of the epigenetic changes during human gonadal primordial germ cells reprogramming

Stem Cells, 2016
Epigenetic reprogramming is a central process during mammalian germline development. Genome‐wide DNA demethylation in primordial germ cells (PGCs) is a prerequisite for the erasure of epigenetic memory, preventing the transmission of epimutations to the ...
C. Eguizabal, L. A. Herrera, L. Oñate, Nuria Montserrat, Petra Hajkova, J. C. I. Belmonte   +5 more
semanticscholar   +1 more source

Oogenesis and germinal bed morphology of the brown anole (A. sagrei)

Developmental Dynamics, EarlyView.
Abstract Background The brown anole is a model species of the genus Anolis, a squamate (encompassing lizards and snakes) group widely studied in evolutionary, behavioral, and developmental biology. Full genome annotation, the establishment of gene editing techniques, and comprehensive description of reproductive tract morphology and embryogenesis in ...
Bonnie K. Kircher, Antonia Weberling, Erin J. Vance, Natalia A. Shylo, Katherine Starr, Zoe B. Griffin, Hannah Wilson, Melainia McClain, Florian Hollfelder, Suzannah A. Williams, Thomas J. Sanger, Richard R. Behringer, Paul A. Trainor   +12 more
wiley   +1 more source

Primordial Germ Cell Technologies for Avian Germplasm Cryopreservation and Investigating Germ Cell Development

The Journal of Poultry Science, 2012
The germ cell lineage is unique as it is the cell lineage that ensures the continuation and the variation of genetic information from one generation to the next.
James D. Glover, Michael J. McGrew
doaj   +1 more source

Dnd Is a Critical Specifier of Primordial Germ Cells in the Medaka Fish

Stem Cell Reports, 2016
Summary Primordial germ cell (PGC) specification occurs early in development. PGC specifiers have been identified in Drosophila, mouse, and human but remained elusive in most animals.
N. Hong, Mingyou Li, Yongming Yuan, Tiansu Wang, M. Yi, Hongyan Xu, Huaqiang Zeng, Jianxing Song, Yunhan Hong   +8 more
semanticscholar   +1 more source

Hormone therapy (HT) in women with premature ovarian insufficiency or early menopause: Time to think of a new paradigm for healthy aging. A joint FIGO and IMS position paper

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Premature ovarian insufficiency (POI) and early menopause (EM) affect millions of women worldwide. Compared with normal menopause, they confer a longer duration of estrogen deficiency and are associated not only with a shorter lifespan, but with a reduced healthspan, owing to an increased risk of cardiovascular, skeletal, cognitive and ...
Chiara Benedetto, Suvarna S. Khadilkar, Rossella E. Nappi, Andrea R. Genazzani, Federica Frezet, Laura Cucinella, Hema Divakar, Panagiotis Anagnostis, Nick Panay   +8 more
wiley   +1 more source

The Role of Wnt/β-catenin Signaling Pathway in Rat Primordial Germ Cells Reprogramming and Induction into Pluripotent State [PDF]

Journal of Advanced Biomedical Sciences, 2014
Primordial Germ Cells (PGCs) are unipotent precursors of the gametes. PGCs can give rise to a type of pluripotent stem cells in vitro that are called embryonic germ (EG) cells. PGCs can also acquire such pluripotency in vivo and generate teratomas. Under
Alireza Mohammadi, Vahab Babapour, Abdol Hossein Shahverdi   +2 more
doaj   +2 more sources

JAK-STAT-dependent contact between follicle cells and the oocyte controls Drosophila anterior-posterior polarity and germline development

Nature Communications
The number of embryonic primordial germ cells in Drosophila is determined by the quantity of germ plasm, whose assembly starts in the posterior region of the oocyte during oogenesis.
Charlotte Mallart, Sophie Netter, Fabienne Chalvet, Sandra Claret, Antoine Guichet, Jacques Montagne, Anne-Marie Pret, Marianne Malartre   +7 more
doaj   +1 more source

Early loss of Xist RNA expression and inactive X chromosome associated chromatin modification in developing primordial germ cells.

PLoS ONE, 2007
BackgroundThe inactive X chromosome characteristic of female somatic lineages is reactivated during development of the female germ cell lineage. In mouse, analysis of protein products of X-linked genes and/or transgenes located on the X chromosome has ...
Mariana de Napoles, Tatyana Nesterova, Neil Brockdorff   +2 more
doaj   +1 more source

Functional analysis of the Drosophila embryonic germ cell transcriptome by RNA interference. [PDF]

PLoS ONE, 2014
In Drosophila melanogaster, primordial germ cells are specified at the posterior pole of the very early embryo. This process is regulated by the posterior localized germ plasm that contains a large number of RNAs of maternal origin.
Ferenc Jankovics, László Henn, Ágnes Bujna, Péter Vilmos, Kerstin Spirohn, Michael Boutros, Miklós Erdélyi   +6 more
doaj   +1 more source