Results 91 to 100 of about 4,898,785 (204)
The 37kDa/67kDa laminin receptor as a therapeutic target in prion diseases: potency of antisense LRP RNA, siRNAs specific for LRP mRNA and a LRP decoy mutant [PDF]
, 2006 Prion diseases are a group of rare, fatal neurodegenerative diseases, also known as transmissible spongiform encephalopathies (TSEs), that affect both animals and humans and include bovine spongiform encephalopathy (BSE) in cattle, scrapie in sheep ...
Vana, Karen
core +1 more source
SERPINA3/SerpinA3n role in prion diseases [PDF]
, 2021 Prion diseases are a family of rare and fatal neurodegenerative disorders, characterized by the accumulation of abnormally folded prion protein. Previous data suggested that SERPINA3/SerpinA3n might be involved in the pathogenesis and the progression of ...
Zattoni, Marco
core
Effects of Pseudorabies Virus Infection on the Tracheobronchial Lymph Node Transcriptome
Bioinformatics and Biology Insights, 2015 This study represents the first swine transcriptome hive plots created from gene set enrichment analysis (GSEA) data and provides a novel insight into the global transcriptome changes occurring in tracheobronchial lymph nodes (TBLN) and spanning the ...
Laura C. Miller +3 more
doaj +1 more source
Transcriptional profile of Glaesserella parasuis in swine serosal and joint fluids
Frontiers in Veterinary ScienceGlaesserella parasuis is the causative agent of Glässer's disease and contributes to significant post-weaning mortality in the swine industry. Glässer's disease is characterized by meningitis, polyserositis, and polyarthritis.
Daniel W. Nielsen +3 more
doaj +1 more source
A study of the incubation period, or age at onset, of the transmissible spongiform encephalopathies/prion diseases. [PDF]
In order to model epidemics of infectious diseases, particularly to estimate probable numbers of cases with onset at any particular time, it is necessaiy to incorporate a term for the incubation period frequency distribution. Sartwell's hypothesis states
Wooldridge, Marion Joan Anstee
core +1 more source
Brain Pathology, 1995 The human prion diseases are fatal neurodegenerative maladies that may present as sporadic, genetic, or infectious illnesses. The sporadic form is called Creutzfeldt‐Jakob disease (CJD) while the inherited disorders are called familial (f) CJD, Gerstmann‐Sträussler‐Scheinker (GSS) disease and fatal familial insomnia (FFI).
openaire +4 more sources
Strain-Specific Targeting and Destruction of Cells by Prions
BiologyPrion diseases are caused by the disease-specific self-templating infectious conformation of the host-encoded prion protein, PrPSc. Prion strains are operationally defined as a heritable phenotype of disease under controlled conditions.
Sara M. Simmons, Jason C. Bartz
doaj +1 more source
, 2019 Recent advances in understanding of the molecular biology of prion diseases and improved clinical diagnostic techniques might allow researchers to think about therapeutic trials in Creutzfeldt-Jakob disease (CJD) patients. Some attempts have been made in the past and various compounds have been tested in single case reports and patient series ...
Zafar, Saima, Noor, Aneeqa, Zerr, Inga
openaire +4 more sources