Results 111 to 120 of about 82,850 (254)

RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment

Precision Medical Sciences, EarlyView.
This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run, Shiwei Jiang, Kun Xu, Yu Fan, Yanwen Chen, Ziao Liu, Zengli Miao, Wei Tian   +7 more
wiley   +1 more source

Deposition pattern and subcellular distribution of disease-associated prion protein in cerebellar organotypic slice cultures infected with scrapie

Frontiers in Neuroscience, 2015
Organotypic cerebellar slices represent a suitable model for characterizing and manipulating prion replication in complex cell environments. Organotypic slices recapitulate prion pathology and are amenable to drug testing in the absence of a blood-brain ...
Hanna eWolf, Andre eHossinger, Andrea eFehlinger, Sven eBuettner, Valerie eSim, Debbie eMcKenzie, Ina Maja Vorberg, Ina Maja Vorberg   +7 more
doaj   +1 more source

Cellular distribution of the prion protein in palatine tonsils of mule deer (Odocoileus hemionus) and Rocky Mountain elk (Cervus elaphus nelsoni) [PDF]

, 2019
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) that affects members of the Cervidae family, including deer (Odocoileus spp.), elk (Cervus Canadensis spp.), and moose (Alces alces spp.).
Belden, E. Lee, Hille, Matthew M., Jewell, Jean E.   +2 more
core   +1 more source

Human α2β1HI CD133+VE epithelial prostate stem cells express low levels of active androgen receptor [PDF]

, 2012
Stem cells are thought to be the cell of origin in malignant transformation in many tissues, but their role in human prostate carcinogenesis continues to be debated.
A Birgersdotter, Anastasia C. Hepburn, AS Goldstein, AT Collins, AT Collins, C Cai, C Lin, CD Chen, CJ Shepherd, Claudia A. Ryan-Munden, CM van der Loos, Craig N. Robson, D Corbeil, DA Lawson, Deepali Pal, DJ Vander Griend, DM Owens, DT Ross, G Attard, G Buchanan, GD Richardson, GR Cunha, H Bonkhoff, H Bonkhoff, Hing Y. Leung, IV Litvinov, J Perez-Losada, J Yu, JA Kemppainen, JK Blackwood, Kelly Coffey, KG Leong, KM Bae, L Patrawala, Laura Wilson, LE Lamb, MC Haffner, N Platet, NT Gaisa, R Heer, R Heer, Rakesh Heer, S Kolli, S Mousses, SO Lee, Stuart C. Williamson, VK Rajasekhar, X Wang, Yao Liang Tang   +48 more
core   +4 more sources

Prion disease [PDF]

British Journal of Psychiatry, 1997
S, Fleminger, D, Curtis
openaire   +2 more sources

Perceived Risks and Agency Trust Associated With Chronic Wasting Disease Over Time 慢性消耗性疾病相关感知风险与机构信任的时序变化研究

Wildlife Letters, EarlyView.
We examined changes in perceived risks associated with chronic wasting disease (CWD) and perceived trust in wildlife agencies over time across 10 studies in eight states. Results indicated that perceived risks to both deer and humans declined the longer the disease had been in a state. Results also indicated that agency trust evaluations were positive,
Jerry J. Vaske, Craig A. Miller
wiley   +1 more source

Reverse zoonosis of the 2022–2023 human seasonal H3N2 detected in swine

npj Viruses
The Iowa State University Veterinary Diagnostic Laboratory detected nineteen human-to-swine reverse zoonoses of the 2022–2023 human seasonal H3N2 between November 2022 and November 2023. Cases from seven U.S.
Michael A. Zeller, Daniel Carnevale de Almeida Moraes, Giovana Ciacci Zanella, Carine K. Souza, Tavis K. Anderson, Amy L. Baker, Phillip C. Gauger   +6 more
doaj   +1 more source

Bacterial Colitis Increases Susceptibility to Oral Prion Disease [PDF]

, 2017
Dietary exposure to prion-contaminated materials has caused kuru and variant Creutzfeldt-Jakob disease in humans and transmissible spongiform encephalopathies (TSEs) in cattle, mink, and felines. The epidemiology of dietary prion infections suggests that
Aguzzi, Adriano, Barthel, Manja, Corthesy, Irène, Hardt, Wolf-Dietrich, Heikenwalder, Mathias, Krautler, Nike J., MacPherson, Andrew J. S., Manco, Giuseppe, Schwarz, Petra, Seifert, Burkhardt, Sigurdson, Christina J., Stecher, Bärbel   +11 more
core  

Chronic Wasting Disease management responses in North America: A public policy analysis

Wildlife Society Bulletin, EarlyView.
In this study we use the Multiple Streams Framework from public policy theory to assess the responses of wildlife management agencies in states and provinces with CWD‐positive cases in the United States and Canada to alleviate public concerns and manage the spread of this disease.
Kelly H. Dunning, Iree Wheeler, Catherine A. Cummings, Stephen S. Ditchkoff, Braxton McCoy, Daniel Morris, Philip Reichert, Vincent Rivers, Travis E. Stoakley, Temple Stoellinger, Tarissa Spoonhunter, Janna R. Willoughby, Sarah Zohdy   +12 more
wiley   +1 more source

Effects of Pseudorabies Virus Infection on the Tracheobronchial Lymph Node Transcriptome

Bioinformatics and Biology Insights, 2015
This study represents the first swine transcriptome hive plots created from gene set enrichment analysis (GSEA) data and provides a novel insight into the global transcriptome changes occurring in tracheobronchial lymph nodes (TBLN) and spanning the ...
Laura C. Miller, Darrell O. Bayles, Eraldo L. Zanella, Kelly M. Lager   +3 more
doaj   +1 more source