Results 81 to 90 of about 4,898,785 (204)

Studies of the transmissibility of the agent of bovine spongiform encephalopathy to the domestic chicken [PDF]

, 2011
Background: Transmission of the prion disease bovine spongiform encephalopathy (BSE) occurred accidentally to cattle and several other mammalian species via feed supplemented with meat and bone meal contaminated with infected bovine tissue.
Stack Michael J, Robert B Green, Paul R Webb, Simmons, M.M., Timm Konold, Spencer, Y.I., Moore Jo, Marion M Simmons, Ian Dexter, Moore, J., Michael Dawson, Jo Moore, Chaplin, M.J., Webb, P.R., Dexter, I., Wells Gerald AH, Austin, A.R., Dawson, M., Austin Anthony R, Gerald AH Wells, Michael J Stack, Anthony R Austin, Wells, G.A.H, Green Robert B, Langeveld, J.P.M., Ian W Blamire, Stack, M.J., Melanie J Chaplin, Simmons, M., Konold Timm, Dawson Michael, Spencer Yvonne I, Hawkins, S.A.C., Konold, T., Simmons Marion M, Chaplin Melanie J, Hawkins Stephen AC, Dexter Ian, Blamire Ian W, Langeveld Jan PM, Jan PM Langeveld, Webb, P.R.I., Yvonne I Spencer, Green, R.B., Blamire, I.W., Webb Paul R, Stephen AC Hawkins   +46 more
core   +1 more source

PRION DISEASES [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 2004
R S G, Knight, R G, Will
openaire   +3 more sources

In-Depth Global Analysis of Transcript Abundance Levels in Porcine Alveolar Macrophages Following Infection with Porcine Reproductive and Respiratory Syndrome Virus

Advances in Virology, 2010
Porcine reproductive and respiratory syndrome virus (PRRSV) is a major pathogen of swine worldwide and causes considerable economic loss. Identifying specific cell signaling or activation pathways that associate with variation in PRRSV replication and ...
Laura C. Miller, John D. Neill, Gregory P. Harhay, Kelly M. Lager, William W. Laegreid, Marcus E. Kehrli   +5 more
doaj   +1 more source

Chronic Wasting Disease in Cervids: Implications for Prion Transmission to Humans and Other Animal Species

mBio, 2019
Chronic wasting disease (CWD) is a prion-related transmissible spongiform encephalopathy of cervids, including deer, elk, reindeer, sika deer, and moose. CWD has been confirmed in at least 26 U.S.
Michael T. Osterholm, Cory J. Anderson, Mark D. Zabel, Joni M. Scheftel, Kristine A. Moore, Brian S. Appleby   +5 more
doaj   +1 more source

Decontamination of prions, prion-associated amyloid and inefectivity from surgical stainless steel - implications for the risk of iatrogenic transmission of CJD

, 2009
The physicochemical nature of the infectious agent in prion diseases creates asignificant challenge for decontamination services. It has been shown to be both resistant tostandard methods of decontamination, used to inactivate viruses and bacteria, and ...
Howlin, Robert
core   +1 more source

Aspects of prion protein dynamics in cell culture models. [PDF]

, 2005
The cell biology of Prion formation and transfer is not well understood. In order to further elucidate the dynamics of PrPc and PrPsc in a cellular context, fusions between Green Fluorescent Protein (GFP) and PrP were constructed and infected/uninfected ...
Landy, Timothy Adam, Landy, T.A.
core  

A rapid dual staining procedure for the quantitative discrimination of prion amyloid from tissues reveals how interactions between amyloid and lipids in tissue homogenates may hinder the detection of prions

, 2009
Transmissible spongiform encephalopathies (TSEs) are fatal neurodegenerative diseases with no cure to this day, and are often associated with the accumulation of amyloid plaques in the brain and other tissues in affected individuals. The emergence of new
Keevil, C.William, Collin, R., Hervé, R., Secker, Thomas, Pinchin, H.E.   +4 more
core   +1 more source

Reverse zoonosis of the 2022–2023 human seasonal H3N2 detected in swine

npj Viruses
The Iowa State University Veterinary Diagnostic Laboratory detected nineteen human-to-swine reverse zoonoses of the 2022–2023 human seasonal H3N2 between November 2022 and November 2023. Cases from seven U.S.
Michael A. Zeller, Daniel Carnevale de Almeida Moraes, Giovana Ciacci Zanella, Carine K. Souza, Tavis K. Anderson, Amy L. Baker, Phillip C. Gauger   +6 more
doaj   +1 more source

Loss of Octarepeats in Two Processed Prion Pseudogenes in the Red Squirrel, Sciurus vulgaris [PDF]

, 2010
The N-terminal region of the mammalian prion protein (PrP) contains an 'octapeptide' repeat which is involved in copper binding. This eight- or nine-residue peptide is repeated four to seven times, depending on the species, and polymorphisms in repeat ...
Rheede, T., Marlinda Hupkes, Timothy T. Kortum, Wilfried W. de Jong, Ole Madsen, de Jong, W.W., Kohlen, W., Madsen, O., Jong, W.W., de, Kortum, T.T., Wouter Kohlen, Teun van Rheede, Hupkes, H.   +12 more
core   +1 more source

Deposition pattern and subcellular distribution of disease-associated prion protein in cerebellar organotypic slice cultures infected with scrapie

Frontiers in Neuroscience, 2015
Organotypic cerebellar slices represent a suitable model for characterizing and manipulating prion replication in complex cell environments. Organotypic slices recapitulate prion pathology and are amenable to drug testing in the absence of a blood-brain ...
Hanna eWolf, Andre eHossinger, Andrea eFehlinger, Sven eBuettner, Valerie eSim, Debbie eMcKenzie, Ina Maja Vorberg, Ina Maja Vorberg   +7 more
doaj   +1 more source