Results 101 to 110 of about 2,165,687 (231)
Aspects of prion protein dynamics in cell culture models. [PDF]
, 2005 The cell biology of Prion formation and transfer is not well understood. In order to further elucidate the dynamics of PrPc and PrPsc in a cellular context, fusions between Green Fluorescent Protein (GFP) and PrP were constructed and infected/uninfected ...
Landy, Timothy Adam, Landy, T.A.
core
VirusesPrion transmission into rodents is essential for understanding prion strains. However, it is often limited by a “species barrier” that makes transmission challenging and complicates the study of animal and human prion diseases. Here, we report that North
Jennifer Myskiw +7 more
doaj +1 more source
An overview of animal prion diseases
Virology Journal, 2011 Prion diseases are transmissible neurodegenerative conditions affecting human and a wide range of animal species. The pathogenesis of prion diseases is associated with the accumulation of aggregates of misfolded conformers of host-encoded cellular prion ...
Imran Muhammad, Mahmood Saqib
doaj +1 more source
The end of the BSE saga: do we still need surveillance for human prion diseases?
Swiss Medical Weekly, 2015 The epidemics of classical bovine spongiform encephalopathy (BSE) and variant Creutzfeldt-Jakob disease (vCJD) related to BSE-infected food are coming to an end.
Herbert Budka, Robert G. Will
doaj +1 more source
iMeta, EarlyView.The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
Prion Protein Scrapie and the Normal Cellular Prion Protein
, 2015 Prions are infectious proteins and over the past few decades, some prions have become renowned for their causative role in several neurodegenerative diseases in animals and humans.
Munn, Alan L +7 more
core +1 more source
Atypical status of bovine spongiform encephalopathy in Poland: a molecular typing study [PDF]
, 2008 The aim of this study was to analyze molecular features of protease-resistant prion protein (PrPres) in Western blots of BSE cases diagnosed in Poland with respect to a possible atypical status.
Polak, M.P. +3 more
core +1 more source
Beginning with a single step: A social theory of change for managing chronic wasting disease
The Journal of Wildlife Management, EarlyView.Following opinions of chronic wasting disease management experts, we identified and prioritized critical interventions to address the disease. We developed a theory of change for the most prioritized intervention that supports the implementation of engagement or social marketing strategies to increase support for management.
Nicholas W. Cole +5 more
wiley +1 more source
Therapeutic Impact of GLP‐1 Receptor Agonists on Parkinson's Disease: A Scoping Review
Neurology and Clinical Neuroscience, EarlyView.ABSTRACT No disease‐modifying treatment exists for Parkinson's disease (PD). Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have gained attention as promising candidates for neuroprotection, given documented expression of GLP‐1 receptors within the central nervous system and the contribution of brain insulin resistance to dopaminergic ...
João Pedro Henriques +4 more
wiley +1 more source
Prion diseases are efficiently transmitted by blood transfusion in sheep [PDF]
, 2008 The emergence of variant Creutzfeld-Jakob disease, following on from the bovine spongiform encephalopathy (BSE) epidemic, led to concerns about the potential risk of iatrogenic transmission of disease by blood transfusion and the introduction of costly ...
Foster, J. +8 more
core +1 more source