Novel Polymorphisms and Genetic Characteristics of the Prion Protein Gene in Pheasants [PDF]
Frontiers in Veterinary Science, 2022 Transmissible spongiform encephalopathies (TSEs) also known as prion diseases, are fatal neurodegenerative diseases. Prion diseases are caused by abnormal prion protein (PrPSc) derived from normal prion protein (PrPC), which is encoded by the prion ...
Kyung Han Kim +5 more
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First report of structural characteristics and polymorphisms of the prion protein gene in raccoon dogs: The possibility of prion disease-resistance [PDF]
Frontiers in Veterinary Science, 2022 Prion diseases are fatal degenerative encephalopathies caused by misfolded prion protein (PrPSc) converted from normal prion protein (PrPC). Previous studies have reported that genetic polymorphisms of the prion protein gene (PRNP) play a critical role ...
Woo-Sung Jo +6 more
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Novel insertion/deletion polymorphisms and genetic features of the shadow of prion protein gene (SPRN) in dogs, a prion-resistant animal [PDF]
Frontiers in Veterinary Science, 2022 Prion diseases are fatal infectious neurodegenerative disorders that are induced by misfolded prion protein (PrPSc). Previous studies have reported that the shadow of prion protein (Sho) encoded by the shadow of prion protein gene (SPRN) plays a critical
Yong-Chan Kim +6 more
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Novel polymorphisms and genetic studies of the shadow of prion protein gene (SPRN) in pheasants [PDF]
Frontiers in Veterinary ScienceBackgroundPrion diseases in mammals are caused by the structural conversion of the natural prion protein (PrPC) to a pathogenic isoform, the “scrapie form of prion protein (PrPSc).” Several studies reported that the shadow of prion protein (Sho), encoded
Da-In Choi +7 more
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Novel Polymorphisms and Genetic Characteristics of the Shadow of Prion Protein Gene (SPRN) in Cats, Hosts of Feline Spongiform Encephalopathy [PDF]
Viruses, 2022 Prion diseases are transmissible spongiform encephalopathies (TSEs) caused by pathogenic prion protein (PrPSc) originating from normal prion protein (PrPC) and have been reported in several types of livestock and pets.
Yong-Chan Kim +4 more
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Novel Single Nucleotide Polymorphisms (SNPs) and Genetic Features of the Prion Protein Gene (PRNP) in Quail (Coturnix japonica) [PDF]
Frontiers in Veterinary Science, 2022 Prion diseases are fatal infectious diseases caused by conformational changes of a prion protein (PrPSc) derived from a normal prion protein (PrPC). Prion diseases have been reported in several mammalian hosts but not in any birds, including the most ...
Yoonhee Kim +5 more
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Identification of the Highly Polymorphic Prion Protein Gene (PRNP) in Frogs (Rana dybowskii) [PDF]
AnimalsPrion diseases are fatal neurodegenerative diseases that can be transmitted by infectious protein particles, PrPScs, encoded by the endogenous prion protein gene (PRNP).
Chang-Su Han +3 more
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Novel polymorphisms and functional characterization of the prion protein gene in sparrows (Passer montanus) [PDF]
Frontiers in Veterinary ScienceBackgroundMisfolding of the prion protein (PrP) into an aberrant conformation causes prion diseases in several mammalian species; however, no prion infections have been documented in birds so far.
Chau-Giang Truong +5 more
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Identification of a novel risk factor for chronic wasting disease (CWD) in elk: S100G single nucleotide polymorphism (SNP) of the prion protein gene (PRNP) [PDF]
Veterinary Research, 2023 Prion diseases are fatal and malignant infectious encephalopathies induced by the pathogenic form of prion protein (PrPSc) originating from benign prion protein (PrPC).
Yu-Ran Lee +9 more
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Identification of Prion Disease-Related Somatic Mutations in the Prion Protein Gene (PRNP) in Cancer Patients [PDF]
Cells, 2020 Prion diseases are caused by misfolded prion protein (PrPSc) and are accompanied by spongiform vacuolation of brain lesions. Approximately three centuries have passed since prion diseases were first discovered around the world; however, the exact role of
Yong-Chan Kim +2 more
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