Results 71 to 80 of about 36,884 (188)

Key points concerning amyloid infectivity and prion-like neuronal invasion

Frontiers in Molecular Neuroscience, 2016
Amyloid aggregation has been related to an increasing number of human illnesses, from Alzheimer and Parkinson’s diseases to Creutzfeldt-Jakob disease. Traditionally only prions have been considered as infectious agents with a high capacity of propagation.
Alba eEspargaró, Maria Antònia eBusquets, Joan eEstelrich, Raimon eSabate   +3 more
doaj   +1 more source

The shape of things to come: structural insights into how prion proteins encipher heritable information. [PDF]

Nat Commun, 2022
Telling GC.
europepmc   +1 more source

Chronic Wasting Disease management responses in North America: A public policy analysis

Wildlife Society Bulletin, EarlyView.
In this study we use the Multiple Streams Framework from public policy theory to assess the responses of wildlife management agencies in states and provinces with CWD‐positive cases in the United States and Canada to alleviate public concerns and manage the spread of this disease.
Kelly H. Dunning, Iree Wheeler, Catherine A. Cummings, Stephen S. Ditchkoff, Braxton McCoy, Daniel Morris, Philip Reichert, Vincent Rivers, Travis E. Stoakley, Temple Stoellinger, Tarissa Spoonhunter, Janna R. Willoughby, Sarah Zohdy   +12 more
wiley   +1 more source

Horizontal Transmission of Cytosolic Sup35 Prions by Extracellular Vesicles

mBio, 2016
Prions are infectious protein particles that replicate by templating their aggregated state onto soluble protein of the same type. Originally identified as the causative agent of transmissible spongiform encephalopathies, prions in yeast (Saccharomyces ...
Shu Liu, André Hossinger, Julia P. Hofmann, Philip Denner, Ina M. Vorberg   +4 more
doaj   +1 more source

Are prion proteins and magnetite involved in the immune cells memory system connected to the covid-19? [PDF]

Med Hypotheses, 2021
Størmer FC.
europepmc   +1 more source

Sugar Metabolisms Altered By Undissociated Forms of Organic Acids Based on the Emergence of [GAR+] Cells in Saccharomyces cerevisiae

Yeast, EarlyView.
ABSTRACT The glucose repression system is a mechanism for effective energy acquisition by glucose assimilation in microorganisms. In yeast, Saccharomyces cerevisiae, which is known as a prion‐like protein [GAR+], is involved in the bypass of glucose repression. It has been reported that the emergence of [GAR+] cells was promoted by lactate and acetate.
Koichi Tanabe, Atsuhiko Nakata, Mizuki Hosotani, Jun Shima   +3 more
wiley   +1 more source

Epitope-specific anti-PrP antibody toxicity: a comparative in-silico study of human and mouse prion proteins. [PDF]

Prion, 2021
Adhikari UK, Tayebi M.
europepmc   +1 more source

Infection control in the brain and the eye

Acta Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

Comparative analysis of heparin affecting the biochemical properties of chicken and murine prion proteins. [PDF]

PLoS One, 2021
Wang LJ, Gu XD, Li XX, Shen L, Ji HF.
europepmc   +1 more source

Comments to the “Letter to the Editor” for the manuscript titled “Increased expression of inflammasome signaling genes and proteins in selective brain regions in the intermediate stage of Alzheimer's disease”

Brain Pathology, EarlyView.
Beta amyloid diffuse plaques, neurofibrillary tangles and neuritic plaques, are increased in densities at the intermediate stage of Alzheimer's neuropathological change. These pathological changes releasing Pathogen‐Associated Molecular Patterns (PAMPs) and Damage‐Associated Molecular Patterns (DAMPs).
Juan Pablo de Rivero Vaccari, David A. Davis, Andrew P. Sawaya, Susanna P. Garamszegi, Xiaoyan Sun, Ayled Barreda, Helen M. Bramlett, Sakir Humayun Gultekin, W. Dalton Dietrich, Robert W. Keane, Regina T. Vontell   +10 more
wiley   +1 more source