Advanced Intelligent Discovery, EarlyView.This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng +4 more
wiley +1 more source
Patient Out-of-Pocket Spending on Generic and Brand-Name Prescription Drugs.
JAMA Netw OpenCai CL, Kesselheim AS, Rome BN.
europepmc +1 more source
The Use of the Surveyor in Removable Partial Denture Prosthetics: A Survey Among Dental Technicians in Casablanca. [PDF]
CureusOubbaih A +6 more
europepmc +1 more source
Current Standards of Monitoring Models in Healthcare Settings
Advanced Intelligent Discovery, EarlyView.AI/ML‐enabled medical devices are entering clinical practice faster than monitoring standards mature. This review highlights gaps in postmarket surveillance, limited use of predetermined change‐control plans, and the need for ongoing performance tracking, drift detection, explainability, and workflow‐aware governance to support safer, more reliable ...
Alan Kay +5 more
wiley +1 more source
A qualitative study of stakeholders' perceptions towards the implementation of the National Health Insurance Scheme in Zambia: equity and financial sustainability in question. [PDF]
Health Policy PlanKazibwe J +7 more
europepmc +1 more source
Large Language Model‐Based Chatbots in Higher Education
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.The use of large language models (LLMs) in higher education can facilitate personalized learning experiences, advance asynchronized learning, and support instructors, students, and researchers across diverse fields. The development of regulations and guidelines that address ethical and legal issues is essential to ensure safe and responsible adaptation
Defne Yigci +4 more
wiley +1 more source
Toward Fully Soft and Multifunctional Shape Sensing via Optical Waveguide Arrays
Advanced Intelligent Systems, EarlyView.This work develops a sheet made with arrays of soft optical fibers that can reconstruct its 3D surface shape. Synergy of the waveguides’ responses to bending and pressing force allows shape reconstruction with resilience to damage. Applied onto surfaces of robotic or living systems, our design can be implemented in virtual reality, teleoperation ...
Qifan Yu, Nina Cao, Kaitlyn Becker
wiley +1 more source
Fast-food and convenience outlets near schools in California: a comparison of private and public schools. [PDF]
Am J EpidemiolKarimuzzaman M +4 more
europepmc +1 more source
Artificial Intelligence for Advanced Functional Materials: Progress and Emerging Frontiers
Advanced Intelligent Systems, EarlyView.Artificial intelligence is transforming the discovery of functional materials by linking synthesis, characterization, simulation, and design in unified workflows. Advances in machine learning, autonomous experimentation, and foundation models are accelerating innovation across energy, electronics, and biomedicine, while revealing new frontiers for ...
Cristiano Malica +38 more
wiley +1 more source
Market strategies used by private hospital providers to consolidate and increase power; a systematic scoping review and evaluative synthesis. [PDF]
Global HealthShore T +4 more
europepmc +1 more source